HCPCS Level II code S9355 identifies per diem home infusion therapy services for chelation therapy that encompass administrative management, professional pharmacy services, care coordination, and necessary supplies and equipment; drugs and nursing visits are billed separately. This code matters nationally as home infusion continues to expand for complex therapies, affecting care coordination, pharmacy management, and payer policy on bundled versus separate reimbursement for drugs and clinical visits. Key payers in this analysis include Aetna, Blue Cross Blue Shield, Cigna Health, UnitedHealthcare, and Medicare.

Readers will learn what S9355 represents clinically and operationally, how it is typically used in home-based chelation infusion programs, and the components captured by the per diem administrative billing. The summary notes common issues payers and providers consider, such as delineation between per diem administrative fees and separately billed drug and nursing services, implications for pharmacy coordination, and typical site-of-service considerations. Where available, the publication provides benchmarks, coding guidance, and recent policy context affecting coverage and billing practices. Data not available in the input is identified as such in relevant sections.