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    v1.0.30
    OpenPayerBilling CodesPathology and Laboratory ServicesHCPCS hcpcs-p2031-hair-analysis-excluding-arsenic
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    HCPCS P2031: Hair Analysis (Excluding Arsenic)

    HCPCS Level II code P2031 describes hair analysis (excluding arsenic), a laboratory toxicology service that analyzes hair samples for multiple elements or substances except arsenic; the service is performed as a laboratory specimen analysis and the typical site of service is a clinical laboratory or outpatient specimen collection facility.

    For related coverage guidance, see recent payer policy updates: Hematology - Adzynma, Tumor Treating Fields for Pancreatic Cancer, Axicabtagene ciloleucel (Yescarta®) coverage.

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    Clinical & Coding Specifications

    Clinical Context

    A typical patient scenario involves an outpatient clinical or occupational medicine visit where a clinician orders P2031 (hair analysis, excluding arsenic) to evaluate long‑term exposure to environmental toxins, heavy metals (other than arsenic), or to assist in forensic, workplace, or therapeutic drug monitoring contexts. For example, a 38‑year‑old patient with chronic unexplained peripheral neuropathy and a history of industrial chemical exposure presents to an occupational medicine clinic. The clinician documents exposure history, obtains informed consent, collects a hair sample per laboratory protocol (generally from the occipital scalp), labels and ships the specimen to a certified toxicology laboratory, and documents chain of custody and clinical rationale in the medical record. Typical workflow steps: pretest counseling, specimen collection (single visit), specimen labeling and packaging, laboratory analysis, and receipt of a laboratory report incorporated into the patient chart. Typical sites of service include outpatient clinics, occupational health centers, forensic collection sites, and certified phlebotomy/lab collection facilities.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    36415Collection of venous blood by venipunctureOften performed alongside for simultaneous serum or whole blood testing for heavy metals or biochemical markers when hair analysis (P2031) is ordered.
    99000Handling and/or conveyance of specimen for transfer from site of collection to laboratory (when specified by payer)May be used to bill specimen handling/shipping fees associated with sending hair samples to an external reference laboratory.
    99070Supplies and materials (e.g., bandages, gauze), noncovered items provided by the physician over and above those usually included with the office visitUsed when special collection kits or packaging materials for hair specimen are provided and billable.
    G0008Administration of influenza vaccine (separate example of G‑code usage)Data not directly related; included only if a payer requires facility-level reporting alongside preventive services — otherwise not applicable.
    99001Infectious disease testing administration (example non-specific)May be used by some payers for specimen collection administration fees depending on local billing policies.

    Note: If a payer requires separation of professional and technical components, TC and 26 modifiers (listed in Coding Specifications) are applied to the appropriate CPT/HCPCS billing lines.

    Related Modifiers

    8 rows

    ModifierDescriptionWhen to Use
    26Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    54Modifier ‑54 (“Surgical care only”) is appended to a CPT surgical procedure when the reporting surgeon performs the intraoperative (surgical) component but does not furnish the preoperative and/or…- Use modifier -54 when the reporting surgeon provided only the intraoperative (surgical) component of a procedure and preoperative and/or postoperative management has been or will be provided by…
    55Modifier –55 indicates the billing provider furnished only postoperative management for a procedure that has a global surgical period. According to AAPC, this modifier is appended to the same CPT…- Use modifier -55 when billing the same CPT surgical code that has a 10- or 90-day global period and you, as a provider other than the original surgeon, furnished ONLY postoperative management (no…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…
    80CPT® Modifier 80 (Assistant Surgeon) is appended to a surgical CPT code when a physician (MD or DO) provides full, continuous assistance throughout the operative procedure. It is intended only for…- Use CPT Modifier -80 when a physician (MD or DO) serves as an assistant surgeon and provides full, continuous assistance throughout the entire operative procedure; append -80 to the surgical CPT…

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    208000000X
    207Q00000X
    208D00000X
    207L00000X
    2278G0305X
    207QA0401X
    207VM0101X
    335V00000X

    Related Payer Policy Updates

    Specialty: Hematology/Oncology1 / 4

    10 rows

    PolicyPayerEffective Date
    Hematology - AdzynmaCigna2026-10-15
    Tumor Treating Fields for Pancreatic Cancerselect_health2026-10-01
    Axicabtagene ciloleucel (Yescarta®) coverageBaylor Scott & White Health Plan2026-10-01
    Electric Tumor Treatment Field Therapy (for Kentucky Only)UnitedHealthcare2026-10-01
    Electric Tumor Treatment Field Therapy (for Kansas Only)UnitedHealthcare2026-10-01
    Electric Tumor Treatment Field Therapy (for Idaho Only)UnitedHealthcare2026-10-01
    Brexucabtagene autoleucel (Tecartus) CoverageBaylor Scott & White Health Plan2026-10-01
    Electric Tumor Treatment Field Therapy (for Pennsylvania Only)UnitedHealthcare2026-10-01
    Epithelial Cell Cytology in Breast Cancer Risk AssessmentOscar Health2026-10-01
    Factor VIII ProductsCigna2026-09-15

    Related Codes

    HCPCS-LEVEL-II-P2029-CONGO-RED-BLOOD-TEST

    HCPCS P2029: Congo red, blood

    HCPCS-P2028-CEPHALIN-FLOCCULATION-BLOOD

    HCPCS Level II P2028: Cephalin Flocculation, Blood

    HCPCS-P2033-THYMOL-TURBIDITY-BLOOD-LAB-TEST

    HCPCS P2033: Thymol Turbidity, Blood

    HCPCS-P2038-MUCOPROTEIN-BLOOD-SEROMUCOID-LAB-TEST

    HCPCS Level II P2038: Mucoprotein (Seromucoid) Blood Test

    HCPCS-P3000-SCREENING-PAP-SMEAR-TECHNICIAN-SUPERVISED

    HCPCS Level II P3000: Screening Papanicolaou Smear by Technician

    HCPCS-P3001-SCREENING-PAP-SMEAR-CERVICAL-VAGINAL

    HCPCS Level II P3001: Screening Papanicolaou Smear, Up to Three Smears

    HCPCS-P7001-QUANTITATIVE-URINE-BACTERIAL-CULTURE-SENSITIVITY

    HCPCS P7001: Urine Bacterial Culture, Quantitative with Sensitivity

    HCPCS-P9010-WHOLE-BLOOD-TRANSFUSION-PER-UNIT

    HCPCS Level II P9010: Blood (whole) for Transfusion, per Unit

    HCPCS-P9011-BLOOD-SPLIT-UNIT

    HCPCS Level II P9011: Blood, Split Unit

    HCPCS-P9012-CRYOPRECIPITATE-EACH-UNIT

    HCPCS Level II P9012: Cryoprecipitate, Each Unit

    Showing 1–10 of 58

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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