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    v1.0.28
    OpenPayerBilling CodesProcedures / Professional ServicesHCPCS hcpcs-g2065-comprehensive-care-management-single-high-risk-disease
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    HCPCS G2065: Comprehensive Care Management for Single High‑Risk Disease

    HCPCS Level II code G2065 describes comprehensive care management for a single high‑risk chronic disease requiring at least 30 minutes of clinical staff time directed by a physician or other qualified health care professional per calendar month; the service is disease‑focused care management for a complex chronic condition lasting ≥3 months that places the patient at risk of hospitalization or has recently caused hospitalization and requires development or revision of a disease‑specific care plan and frequent medication adjustments or unusually complex management due to comorbidities. This is a care management service delivered through structured clinical staff time and clinician direction and is typically provided in outpatient clinic, primary care, or care coordination settings as an ongoing monthly disease management service.

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    Table of contents

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    Clinical & Coding Specifications

    Clinical Context

    A 72-year-old patient with long-standing heart failure with reduced ejection fraction and chronic kidney disease visits a primary care clinic after a recent hospitalization for decompensated heart failure. The patient's condition has persisted for more than three months and places them at high risk for readmission. The physician directs clinical staff to provide comprehensive care management for the principal disease (heart failure). Over the course of the calendar month, clinical staff perform at least 30 minutes of directed activities including medication reconciliation and adjustment coordination with cardiology, development and revision of a disease-specific care plan, patient education on fluid and sodium management, remote monitoring review (weights, blood pressure), and arranging home health support. Documentation includes the chronic condition being the focus of the care plan, evidence that the condition is severe enough to risk hospitalization, that the plan was developed or revised, and that frequent medication adjustments or complex comorbidity management occurred. Typical workflow steps: referral or identification of eligible patient; initial clinician assessment; development or revision of a disease-specific care plan; delegation of at least 30 minutes of clinical staff time for care management activities; communication with the patient or caregiver and relevant providers; documentation and billing of G2065 for the calendar month in which criteria are met. Typical sites of service include outpatient primary care clinics, specialty cardiology clinics, home health settings, and telehealth/remote monitoring programs where clinical staff deliver directed care management services.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    99490Chronic care management services, at least 20 minutes of clinical staff time directed by a physician or other qualified health care professional, per calendar monthMay be billed for non-complex chronic care management when time thresholds and complexity requirements differ; G2065 applies to a single high-risk disease with higher complexity.
    99487Complex chronic care management services, with substantial care planning and moderate to high complexity medical decision making, first hour of clinical staff time directed by a physician or other qualified health care professional, per calendar monthBilled for patients with multiple complex chronic conditions and higher time/complexity thresholds; may be part of the same comprehensive care program when patient meets multi-condition criteria.
    99424Online digital evaluation and management service, for an established patient, for up to 7 days, cumulative time during the 7 daysDigital communications and remote monitoring touchpoints that support the care management activities billed under G2065.
    99457Remote physiologic monitoring treatment management services, clinical staff/physician/other qualified health care professional time in a calendar month requiring interactive communication with the patient/caregiver during the monthRemote monitoring and interactive communication often accompany the disease-specific care plan and medication adjustments documented for G2065.
    99495Transitional care management services with moderate complexity medical decision making and face-to-face visit within 14 days of dischargeCommonly performed after hospitalization; transitional care management activities may overlap with the comprehensive care plan focus and support eligibility for G2065.

    Related Modifiers

    8 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    54Modifier ‑54 (“Surgical care only”) is appended to a CPT surgical procedure when the reporting surgeon performs the intraoperative (surgical) component but does not furnish the preoperative and/or…- Use modifier -54 when the reporting surgeon provided only the intraoperative (surgical) component of a procedure and preoperative and/or postoperative management has been or will be provided by…
    55Modifier –55 indicates the billing provider furnished only postoperative management for a procedure that has a global surgical period. According to AAPC, this modifier is appended to the same CPT…- Use modifier -55 when billing the same CPT surgical code that has a 10- or 90-day global period and you, as a provider other than the original surgeon, furnished ONLY postoperative management (no…
    56Modifier ‑56 indicates the reporting provider furnished only the preoperative management for a surgical procedure and did not perform the intraoperative or postoperative care. It is used in…- Use Modifier -56 when a provider performs only the preoperative management in a split‑care situation (one physician manages preop care while a different physician performs the intraoperative…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…

    Related Provider Taxonomies

    8 rows

    Taxonomy CodeSpecialtyNotes
    207Q00000XFamily Medicine PhysicianFamily Medicine is the medical specialty which is concerned with the total health care of the individual and the family. It is the specialty in breadt…
    207R00000XInternal Medicine PhysicianA physician who provides long-term, comprehensive care in the office and the hospital, managing both common and complex illness of adolescents, adults…
    207RC0000XCardiovascular Disease PhysicianAn internist who specializes in diseases of the heart and blood vessels and manages complex cardiac conditions such as heart attacks and life-threaten…
    163W00000XRegistered Nurse(1) A registered nurse is a person qualified by graduation from an accredited nursing school (depending upon schooling, a registered nurse may receive…
    364S00000XClinical Nurse SpecialistA registered nurse who, through a graduate degree program in nursing, or through a formal post-basic education program or continuing education courses…
    2080C0008XChild Abuse Pediatrics PhysicianA Child Abuse Pediatrician serves as a resource to children, families and communities by accurately diagnosing abuse; consulting with community agenci…
    1835P1400XPain Management PharmacistA licensed pharmacist who has demonstrated specialized knowledge and skills, providing integrated, comprehensive, and accessible healthcare services t…
    163WP1700XPerinatal Registered NurseNursing Service Providers · Registered Nurse

    Related ICD-10-CM Codes

    28 rows

    ICD-10-CM CodeDescription
    B20Human immunodeficiency virus [HIV] disease
    C34.90Malignant neoplasm of unspecified part of unspecified bronchus or lung
    E03.9Hypothyroidism, unspecified
    E11.65Type 2 diabetes mellitus with hyperglycemia
    E11.9Type 2 diabetes mellitus without complications
    E78.5Hyperlipidemia, unspecified
    F17.210Nicotine dependence, cigarettes, uncomplicated
    F32.9Major depressive disorder, single episode, unspecified
    G30.9Alzheimer's disease, unspecified
    I10Essential (primary) hypertension

    Showing 1–10 of 28

    Related Codes

    HCPCS-G9490-HOME-ASSESSMENT-NON-HOMEBOUND

    HCPCS G9490: Home Visit Patient Assessment for Non-Homebound Beneficiary

    HCPCS-G0008-INFLUENZA-VACCINE-ADMINISTRATION

    HCPCS G0008: Administration of Influenza Virus Vaccine

    HCPCS-G0009-PNEUMOCOCCAL-VACCINE-ADMINISTRATION

    HCPCS G0009: Administration of Pneumococcal Vaccine

    HCPCS-G0010-HEPATITIS-B-VACCINE-ADMINISTRATION

    HCPCS G0010: Administration of Hepatitis B Vaccine

    HCPCS-G0011-PREP-COUNSELING-HIV-RISK-REDUCTION-ADHERENCE

    HCPCS G0011: Individual PrEP Counseling, HIV Risk Assessment

    HCPCS-G0012-PRE-EXPOSURE-PROPHYLAXIS-INJECTION-HIV-PREVENTION

    HCPCS G0012: Injection of PrEP Drug for HIV Prevention

    HCPCS-G0013-PREP-INDIVIDUAL-COUNSELING-HIV-RISK-REDUCTION

    HCPCS G0013: Individual PrEP Counseling by Clinical Staff

    HCPCS-G0017-PSYCHOTHERAPY-CRISIS-FIRST-60-MINUTES-NON-OFFICE

    HCPCS G0017: Psychotherapy for Crisis, First 60 Minutes

    HCPCS-G0018-PSYCHOTHERAPY-CRISIS-ADDITIONAL-30-MINUTES-NON-OFFICE

    HCPCS G0018: Psychotherapy for Crisis, Additional 30 Minutes

    HCPCS-G0019-COMMUNITY-HEALTH-INTEGRATION-SDOH-CARE-COORDINATION

    HCPCS G0019: Community Health Integration, Person-Centered Assessment

    Showing 1–10 of 1996

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    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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