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    v1.0.28
    OpenPayerBilling CodesMedical And Surgical SuppliesHCPCS hcpcs-a4541-monthly-supplies-e0733
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    HCPCS A4541: Monthly Supplies for Device Coded `e0733`

    HCPCS Level II code A4541 describes monthly supplies for use with the device coded as e0733; this represents recurring consumable items dispensed on a monthly basis to support durable medical equipment use, typically billed as a supply service associated with home medical equipment and provided in the patient’s home or other outpatient setting.

    For related coverage guidance, see recent payer policy updates: Salivary Hormone Testing, Bone Turnover Markers Testing, Parathyroid Hormone, Phosphorus, Calcium, and Magnesium Testing.

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    Clinical & Coding Specifications

    Clinical Context

    A common scenario involves an adult patient with a chronic indwelling negative pressure wound therapy (NPWT) system coded as E0733 who requires monthly disposable supplies for ongoing home use. The patient is typically managed by a wound care clinic or a home health agency after hospitalization for a complex surgical incision or chronic non-healing ulcer (for example, diabetic foot ulcer or pressure ulcer). At an outpatient visit or during a home health nurse visit, the clinician assesses the wound, confirms ongoing suitability of NPWT, documents wound measurements and progress, and authorizes monthly disposable supplies (dressings, canisters, tubing) billed as A4541 for the supplies corresponding to the device-coded E0733 therapy. The workflow includes wound assessment, documentation of device use, statement of medical necessity for continued NPWT supplies, coordination with the durable medical equipment supplier to dispense monthly supplies, and routine follow-up visits to monitor healing and adjust therapy as needed.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    97605Negative pressure wound therapy (eg, vacuum assisted drainage), open wound, with dressing change; simple (eg, debridement not included)Used for NPWT dressing changes in outpatient or home settings; often performed alongside monthly supply use.
    97606Negative pressure wound therapy (eg, vacuum assisted drainage), open wound, with dressing change; complex (eg, requires debridement, extensive packing)Used when dressing changes are complex and may justify additional clinical services beyond supply provision.
    11042Debridement, subcutaneous tissue (includes simple debridement codes as appropriate)Surgical or sharp debridement that may precede initiation or continuation of NPWT and the need for supplies.
    97597Debridement (eg, high-pressure water, sharp) selective debridement of open wound, non-selective debridement is 97598 for extensive; 97597 is for wound management with measurable benefitPerformed in wound care visits supporting NPWT therapy and supply orders.
    99070Supplies and materials (except spectacles), provided by physician or other qualified health care professional, over and above those usually included with the serviceMay be used to report additional supplies not captured by A4541 when payer allows; often scrutinized by payers.

    Related Modifiers

    6 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…
    80CPT® Modifier 80 (Assistant Surgeon) is appended to a surgical CPT code when a physician (MD or DO) provides full, continuous assistance throughout the operative procedure. It is intended only for…- Use CPT Modifier -80 when a physician (MD or DO) serves as an assistant surgeon and provides full, continuous assistance throughout the entire operative procedure; append -80 to the surgical CPT…

    Related Provider Taxonomies

    8 rows

    Taxonomy CodeSpecialtyNotes
    363A00000XPhysician AssistantA physician assistant is a person who has successfully completed an accredited education program for physician assistant, is licensed by the state and…
    207P00000XEmergency Medicine PhysicianAn emergency physician focuses on the immediate decision making and action necessary to prevent death or any further disability both in the pre-hospit…
    208000000XPediatrics PhysicianA pediatrician is concerned with the physical, emotional and social health of children from birth to young adulthood. Care encompasses a broad spectru…
    367H00000XAnesthesiologist AssistantAn individual certified by the state to perform anesthesia services under the direct supervision of an anesthesiologist. Anesthesiologist Assistants …
    364S00000XClinical Nurse SpecialistA registered nurse who, through a graduate degree program in nursing, or through a formal post-basic education program or continuing education courses…
    172A00000XDriverA person employed to operate a motor vehicle as a carrier of persons or property.
    364SW0102XWomen's Health Clinical Nurse SpecialistPhysician Assistants & Advanced Practice Nursing Providers · Clinical Nurse Specialist
    320700000XPhysical Disabilities Residential Treatment FacilityA residential facility that provides habilitation services and other care and treatment to adults or children diagnosed with physical disabilities and…

    Related ICD-10-CM Codes

    24 rows

    ICD-10-CM CodeDescription
    E10.42Type 1 diabetes mellitus with diabetic polyneuropathy
    E10.51Type 1 diabetes mellitus with diabetic peripheral angiopathy without gangrene
    E11.42Type 2 diabetes mellitus with diabetic polyneuropathy
    E11.51Type 2 diabetes mellitus with diabetic peripheral angiopathy without gangrene
    G21.9Secondary parkinsonism, unspecified
    G40.909Epilepsy, unspecified, not intractable, without status epilepticus
    G47.33Obstructive sleep apnea (adult) (pediatric)
    G82.20Paraplegia, unspecified
    G82.50Quadriplegia, unspecified
    G83.4Cauda equina syndrome

    Showing 1–10 of 24

    Related Payer Policy Updates

    Specialty: Endocrinology1 / 3

    5 rows

    PolicyPayerEffective Date
    Salivary Hormone TestingOscar Health2026-10-01
    Bone Turnover Markers TestingOscar Health2026-10-01
    Parathyroid Hormone, Phosphorus, Calcium, and Magnesium TestingOscar Health2026-10-01
    Testosterone — Coverage Criteria for Measurement and MonitoringOscar Health2026-10-01
    Thyroid Disease TestingOscar Health2026-10-01

    Related Codes

    HCPCS-A4206-STERILE-SYRINGE-1CC-NEEDLE

    HCPCS A4206: Syringe with Needle, 1 cc or Less, Sterile

    HCPCS-A4207-STERILE-2CC-SYRINGE-WITH-NEEDLE

    HCPCS Level II A4207: Syringe with Needle, Sterile 2 cc

    HCPCS-A4208-STERILE-3CC-SYRINGE-WITH-NEEDLE

    HCPCS Level II A4208: Syringe with Needle, Sterile 3 cc

    HCPCS-A4209-STERILE-SYRINGE-WITH-NEEDLE-5CC-OR-GREATER

    HCPCS Level II A4209: Syringe with Needle, Sterile 5 cc or Greater

    HCPCS-A4210-NEEDLE-FREE-INJECTION-DEVICE

    HCPCS Level II A4210: Needle-free Injection Device, Each

    HCPCS-A4211-SUPPLIES-SELF-ADMINISTERED-INJECTIONS

    HCPCS Level II A4211: Supplies for Self-Administered Injections

    HCPCS-A4212-NON-CORING-NEEDLE-STYLET-CATHETER-ACCESS-SUPPLY

    HCPCS Level II A4212: Non-coring Needle or Stylet with/without Catheter

    HCPCS-A4213-STERILE-SYRINGE-20CC-OR-GREATER

    HCPCS Level II A4213: Syringe, Sterile, 20 cc or Greater, Each

    HCPCS-A4215-STERILE-NEEDLE-SINGLE-EACH

    HCPCS Level II A4215: Needle, Sterile, Any Size

    HCPCS-A4216-STERILE-DILUENT-FLUSH-10ML

    HCPCS Level II A4216: Sterile Diluent/Flush, 10 ml

    Showing 1–10 of 633

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    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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