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    OpenPayerBilling CodesMatrix for Wound Management (Placental, Equine, Synthetic)HCPCS hcpcs-a2007-restrata-per-sq-cm-topical-wound-material
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    HCPCS Level II A2007: Restrata, per Square Centimeter (Add-on)

    Medicare pays $133 on average nationally for this procedure.

    HCPCS Level II code A2007 describes billing for Restrata charged per square centimeter as an add-on service billed separately in addition to a primary procedure; the service represents a topical or wound-related product applied or used in the course of a primary procedure, typically documented as a procedure add-on and furnished in ambulatory surgical centers, hospital outpatient departments, or other outpatient procedural settings.

    For related coverage guidance, see recent payer policy updates: Breast Reduction (Mammoplasty) Surgery, Rhinoplasty Medical Necessity and Site of Service, Surgical Treatments for Lymphedema.

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    Clinical & Coding Specifications

    Clinical Context

    A typical patient is an adult with a chronic or large-sized skin or soft-tissue wound (e.g., pressure ulcer, diabetic foot ulcer, surgical dehiscence, full-thickness burn) requiring application of a skin substitute product billed by surface area. The procedure using A2007 (Restrata, per square centimeter) is performed in an outpatient wound care clinic, hospital outpatient department, or ambulatory surgical center. The clinical workflow commonly includes: initial wound assessment and debridement, measurement of wound surface area, selection and preparation of the Restrata dermal substitute, application and fixation of the product to the wound bed, dressing placement, and patient education on wound care and follow-up. Documentation includes wound measurements (cm2), indication for graft/substitute, prior conservative treatments, procedure note describing application technique, quantity (square centimeters) of A2007 used, and post-procedure plan including frequency of dressing changes and follow-up visits.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    11042Debridement, subcutaneous tissue (includes removal of devitalized tissue prior to application of skin substitute)Often performed immediately prior to application of A2007 to prepare a vascularized wound bed.
    11730Avulsion of nail plate, partial or complete, any number of fingers or toesMay be performed in conjunction with wound care in digital infections prior to skin substitute placement.
    15002Adjacent tissue transfer or rearrangement, trunk, arms, legs; first 30 sq cm or less, each additional 30 sq cm (includes soft tissue advancement procedures)Used when local tissue rearrangement is performed alongside or instead of dermal substitute placement for wound closure.
    15271Full-thickness skin graft, trunk, arms, legs; first 100 sq cm or less, or scalp, neck, hands, genitalia; first 20 sq cm or lessPerformed when autograft is used in combination with or following use of dermal substitute for definitive closure.
    97597Removal of devitalized tissue from wound(s), selective debridement, without anesthesia (first 20 sq cm or less)Commonly billed in serial outpatient wound care visits prior to or after application of A2007 for wound bed maintenance.

    Related Modifiers

    8 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    54Modifier ‑54 (“Surgical care only”) is appended to a CPT surgical procedure when the reporting surgeon performs the intraoperative (surgical) component but does not furnish the preoperative and/or…- Use modifier -54 when the reporting surgeon provided only the intraoperative (surgical) component of a procedure and preoperative and/or postoperative management has been or will be provided by…
    55Modifier –55 indicates the billing provider furnished only postoperative management for a procedure that has a global surgical period. According to AAPC, this modifier is appended to the same CPT…- Use modifier -55 when billing the same CPT surgical code that has a 10- or 90-day global period and you, as a provider other than the original surgeon, furnished ONLY postoperative management (no…
    56Modifier ‑56 indicates the reporting provider furnished only the preoperative management for a surgical procedure and did not perform the intraoperative or postoperative care. It is used in…- Use Modifier -56 when a provider performs only the preoperative management in a split‑care situation (one physician manages preop care while a different physician performs the intraoperative…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    2084P0800X
    207K00000X
    364S00000X
    207L00000X
    208100000X
    146M00000X
    1835X0200X
    2086S0120X

    Related ICD-10-CM Codes

    24 rows

    ICD-10-CM CodeDescription
    E11.621Type 2 diabetes mellitus with foot ulcer
    E11.69Type 2 diabetes mellitus with other specified complication
    L76.01Intraoperative hemorrhage and hematoma of skin and subcutaneous tissue complicating a dermatologic procedure
    L89.013Pressure ulcer of right elbow, stage 3
    L89.023Pressure ulcer of left elbow, stage 3
    L89.113Pressure ulcer of right upper back, stage 3
    L89.213Pressure ulcer of right hip, stage 3
    L89.313Pressure ulcer of right buttock, stage 3
    L97.411Non-pressure chronic ulcer of right heel and midfoot limited to breakdown of skin
    L97.421Non-pressure chronic ulcer of left heel and midfoot limited to breakdown of skin

    Showing 1–10 of 24

    Related Payer Policy Updates

    Specialty: Plastic/Reconstructive Surgery1 / 3

    10 rows

    PolicyPayerEffective Date
    Breast Reduction (Mammoplasty) SurgeryKaiser Permanente2027-02-01
    Rhinoplasty Medical Necessity and Site of ServicePremera Bluecross2026-10-14
    Surgical Treatments for LymphedemaProvidence Health Plan2026-10-01
    Surgical Treatment of Lipedema and LymphedemaPremera Bluecross2026-10-01
    Breast Reduction Surgery (for North Carolina Only)UnitedHealthcare2026-10-01
    Cosmetic, Reconstructive, or Plastic SurgeryUnitedHealthcare2026-10-01
    Surgical Treatments for LymphedemaProvidence Health Plan2026-10-01
    Reduction Mammoplasty (Breast Reduction Surgery) for Symptomatic MacromastiaWPS Health Insurance2026-10-01
    Reduction MammoplastyModa Health2026-10-01
    Treatment for Lipedema (Lipectomy/Liposuction)Moda Health2026-10-01

    Related Codes

    HCPCS-A2001-INNOVAMATRIX-PER-SQ-CM

    HCPCS Level II A2001: Innovamatrix ac, per square centimeter (add-on)

    HCPCS-A2002-MIRRAGEN-ADVANCED-WOUND-MATRIX-PER-CM2

    HCPCS Level II A2002: Mirragen Advanced Wound Matrix, per sq cm

    HCPCS-A2004-XCELLISTEM-1MG-SPECIALTY-BIOLOGIC-SUPPLY

    HCPCS A2004: Xcellistem, 1 mg

    HCPCS-A2005-MICROLYTE-MATRIX-WOUND-BIOMATERIAL-PER-CM2

    HCPCS Level II A2005: Microlyte Matrix, Per Square Centimeter

    HCPCS-A2006-NOVOSORB-DERMAL-MATRIX-PER-CM

    HCPCS A2006: Novosorb Synpath Dermal Matrix, per cm2

    HCPCS-A2008-THERAGENESIS-PER-SQUARE-CENTIMETER-ADD-ON

    HCPCS Level II A2008: Theragenesis, Per Square Centimeter

    HCPCS-A2009-SYMPHONY-PER-SQUARE-CENTIMETER-ADD-ON

    HCPCS Level II A2009: Symphony, per Square Centimeter (Add-on)

    HCPCS-A2010-APIS-PER-SQUARE-CENTIMETER-TOPICAL-BIOLOGIC-ADD-ON

    HCPCS Level II A2010: Apis Topical Product Per Square Centimeter

    HCPCS-A2011-SUPRA-SDRM-PER-SQ-CM-ADD-ON

    HCPCS Level II A2011: Suprasdrm per Square Centimeter (Add-on)

    HCPCS-A2012-SUPRATHEL-PER-SQUARE-CENTIMETER

    HCPCS A2012: Suprathel Skin Substitute, Per cm2

    Showing 1–10 of 43

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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