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    OpenPayerBilling CodesPolyneuropathies and other disorders of the peripheral nervous systemICD-10-CM g61-inflammatory-polyneuropathy
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    ICD-10-CM Code For Inflammatory Polyneuropathy: Group Overview

    The International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) code group G61 includes inflammatory polyneuropathies such as Guillain-Barré syndrome, chronic inflammatory demyelinating polyneuropathy, and other immune-mediated peripheral nerve disorders that cause motor, sensory, or autonomic dysfunction. These ICD-10-CM diagnosis codes are used to document clinical scenarios involving acute or chronic inflammatory involvement of peripheral nerves, capturing disease severity, progression, and complications such as respiratory failure or autonomic instability. Accurate coding within the ICD-10-CM G61 group supports proper claim adjudication, complete clinical documentation, and appropriate reimbursement.

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    ICD-10-CM G61: Inflammatory Polyneuropathy Overview

    The diagnoses in this group represent immune-mediated and inflammatory disorders primarily affecting peripheral nerves, including acute and chronic demyelinating processes. They target the peripheral nervous system and can present with motor, sensory, and autonomic dysfunction. Accurate coding is important for proper clinical documentation and to support appropriate reimbursement for complex neurologic care.

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    When to Use

    Use a code from this group when clinical evaluation documents inflammatory polyneuropathy as the primary diagnosis, including cases with specified subtypes or complications. Apply codes that reflect acuity, specific syndrome, and any associated complications such as respiratory failure or autonomic dysfunction.

    ICD-10-CM Codes

    6 rows

    ICD-10-CM CodeDescription
    G61.0Guillain-Barre syndrome
    G61.1Serum neuropathy
    G61.81Chronic inflammatory demyelinating polyneuritis
    G61.82Multifocal motor neuropathy
    G61.89Other inflammatory polyneuropathies
    G61.9Inflammatory polyneuropathy, unspecified

    DRG Codes

    5 rows

    DRG CodeDescription
    073Cranial and Peripheral Nerve Disorders with MCC
    074Cranial and Peripheral Nerve Disorders without MCC
    094Bacterial and Tuberculous Infections of Nervous System with MCC
    095Bacterial and Tuberculous Infections of Nervous System with CC
    096Bacterial and Tuberculous Infections of Nervous System without CC/MCC

    Typical Clinical Scenarios

    • An adult presents to the emergency department with rapidly progressive, symmetric ascending weakness over several days, respiratory difficulty, areflexia on exam, and recent history of a viral prodrome; nerve conduction studies show demyelinating features consistent with an acute inflammatory demyelinating polyradiculoneuropathy and IVIG is initiated. A diagnosis from this group is assigned for an acute inflammatory polyneuropathy presenting as Guillain–Barré syndrome. Typical codes: G61.0
    • A middle-aged patient with known chronic inflammatory neuropathy reports gradually progressive, relapsing weakness and sensory loss over months, with electrophysiology demonstrating chronic demyelination and motor conduction block; maintenance immunotherapy and periodic clinic follow‑up are planned. A diagnosis from this group is assigned for a chronic inflammatory demyelinating polyneuropathy. Typical codes: G61.81
    • An older patient with active systemic lupus erythematosus develops new distal paresthesias, weakness, and decreased reflexes; evaluation attributes the neuropathy to an inflammatory autoimmune process related to the underlying connective tissue disease and it is documented as a neurologic complication. A diagnosis from this group is assigned for an inflammatory polyneuropathy as a comorbidity of systemic autoimmune disease. Typical codes: G61.89, G61.9

    Related Codes

    G60-HEREDITARY-AND-IDIOPATHIC-NEUROPATHY

    ICD-10-CM Code For Hereditary And Idiopathic Neuropathy: Group Overview

    G62-OTHER-AND-UNSPECIFIED-POLYNEUROPATHIES

    ICD-10-CM Code For Other And Unspecified Polyneuropathies: Group Overview

    G63-POLYNEUROPATHY-IN-DISEASES-CLASSIFIED-ELSEWHERE

    ICD-10-CM Code For Polyneuropathy In Diseases Classified Elsewhere: Group Overview

    G64-OTHER-PERIPHERAL-NERVE-DISORDERS

    ICD-10-CM Code For Other Disorders Of Peripheral Nervous System: Group Overview

    G65-SEQUELAE-OF-POLYNEUROPATHIES

    ICD-10-CM Code For Sequelae Of Inflammatory And Toxic Polyneuropathies: Group Overview

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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