ICD-10-CM Code For Abuse Of Non-Psychoactive Substances: Group Overview

The International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) code group F55 includes diagnoses related to the abuse of non-psychoactive substances, such as misuse of laxatives, topical agents, steroids, or other products that produce physiological harm without primary psychoactive effects. These ICD-10-CM diagnosis codes are used to document clinical scenarios where physiological disturbances result from non-psychoactive substance misuse, capturing severity, organ involvement, or treatment complexity relevant to this group. Accurate coding within the ICD-10-CM F55 group supports proper claim adjudication, complete clinical documentation, and appropriate reimbursement.

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ICD-10-CM F55: Abuse Of Non-Psychoactive Substances Overview

This group captures disorders related to the misuse or abuse of non-psychoactive substances, such as laxatives, steroids, and other agents that do not primarily affect mood or perception. These conditions often involve physiological disturbances and can affect multiple organ systems depending on the substance and exposure. Accurate coding matters for reimbursement because it documents the clinical complexity and resource needs associated with treating the physiological consequences of substance abuse.

When to Use

Use a code from this group when a patient presents with clinical problems directly attributable to the misuse of non-psychoactive substances and the provider documents the abuse. Select specific codes based on the substance involved and the documented physiological effects or complications.

ICD-10-CM Codes

6 rows

ICD-10-CM Code	Description
F55.0	Abuse of antacids
F55.1	Abuse of herbal or folk remedies
F55.2	Abuse of laxatives
F55.3	Abuse of steroids or hormones
F55.4	Abuse of vitamins
F55.8	Abuse of other non-psychoactive substances

DRG Codes

4 rows

DRG Code	Description
894	Alcohol, Drug Abuse or Dependence, Left AMA
895	Alcohol, Drug Abuse or Dependence with Rehabilitation Therapy
896	Alcohol, Drug Abuse or Dependence without Rehabilitation Therapy with MCC
897	Alcohol, Drug Abuse or Dependence without Rehabilitation Therapy without MCC

Typical Clinical Scenarios

A middle-aged adult presents to the emergency department with acute gastrointestinal bleeding and severe electrolyte abnormalities after prolonged, excessive use of laxatives to control weight; the patient admits to daily stimulant laxative use for months and is found to have dehydration and hypokalemia requiring IV fluids and electrolyte repletion, so a diagnosis from this group is assigned for abuse of non-psychoactive substances related to laxatives. Typical codes: F55.2, F55.8
An elderly nursing home resident with chronic misuse of prescribed sedative-hypnotic medications (non-psychoactive agents used for sleep) exhibits progressive daytime somnolence, impaired balance, and frequent falls prompting a geriatric assessment and medication review; because the functional impairment is related to continued non-psychoactive medication abuse rather than primary dementia, a code from this group is used. Typical codes: F55.3, F55.8
A young adult is evaluated in outpatient addiction treatment for repeated intentional ingestion of household cleaning agents (non-psychoactive toxic substances) as self-harm behavior; the patient has no primary substance use disorder for psychoactive drugs but requires counseling and medical monitoring for toxic exposure, hence a diagnosis from this group is recorded as the contributing behavioral syndrome. Typical codes: F55.1, F55.8

Related Codes

F50-EATING-DISORDERS

ICD-10-CM Code For Eating Disorders: Group Overview

F51-SLEEP-DISORDERS-NOT-DUE-TO-SUBSTANCE

ICD-10-CM Code For Sleep Disorders Not Due To A Substance Or Known Physiological Condition: Group Overview

F52-SEXUAL-DYSFUNCTION-NOT-DUE

ICD-10-CM Code For Sexual Dysfunction Not Due To A Substance Or Known Physiological Condition: Group Overview

F53-MENTAL-AND-BEHAVIORAL-DISORDERS-ASSOCIATED-WITH-THE-PUERPERIUM

ICD-10-CM Code For Mental And Behavioral Disorders Associated With The Puerperium Not Elsewhere Classified: Group Overview

F54-PSYCHOLOGICAL-AND-BEHAVIORAL-FACTORS

ICD-10-CM Code For Psychological And Behavioral Factors Associated With Disorders Or Diseases Classified Elsewhere: Group Overview

F59-UNSPECIFIED-BEHAVIORAL-SYNDROMES

ICD-10-CM Code For Unspecified Behavioral Syndromes Associated With Physiological Disturbances And Physical Factors: Group Overview

Frequently Asked Questions

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

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When to Use

ICD-10-CM Codes

6 rows

ICD-10-CM Code	Description
F55.0	Abuse of antacids
F55.1	Abuse of herbal or folk remedies
F55.2	Abuse of laxatives
F55.3	Abuse of steroids or hormones
F55.4	Abuse of vitamins
F55.8	Abuse of other non-psychoactive substances

DRG Codes

4 rows

DRG Code	Description
894	Alcohol, Drug Abuse or Dependence, Left AMA
895	Alcohol, Drug Abuse or Dependence with Rehabilitation Therapy
896	Alcohol, Drug Abuse or Dependence without Rehabilitation Therapy with MCC
897	Alcohol, Drug Abuse or Dependence without Rehabilitation Therapy without MCC

Typical Clinical Scenarios

A middle-aged adult presents to the emergency department with acute gastrointestinal bleeding and severe electrolyte abnormalities after prolonged, excessive use of laxatives to control weight; the patient admits to daily stimulant laxative use for months and is found to have dehydration and hypokalemia requiring IV fluids and electrolyte repletion, so a diagnosis from this group is assigned for abuse of non-psychoactive substances related to laxatives. Typical codes: F55.2, F55.8
An elderly nursing home resident with chronic misuse of prescribed sedative-hypnotic medications (non-psychoactive agents used for sleep) exhibits progressive daytime somnolence, impaired balance, and frequent falls prompting a geriatric assessment and medication review; because the functional impairment is related to continued non-psychoactive medication abuse rather than primary dementia, a code from this group is used. Typical codes: F55.3, F55.8
A young adult is evaluated in outpatient addiction treatment for repeated intentional ingestion of household cleaning agents (non-psychoactive toxic substances) as self-harm behavior; the patient has no primary substance use disorder for psychoactive drugs but requires counseling and medical monitoring for toxic exposure, hence a diagnosis from this group is recorded as the contributing behavioral syndrome. Typical codes: F55.1, F55.8

Related Codes

F50-EATING-DISORDERS

ICD-10-CM Code For Eating Disorders: Group Overview

F51-SLEEP-DISORDERS-NOT-DUE-TO-SUBSTANCE

ICD-10-CM Code For Sleep Disorders Not Due To A Substance Or Known Physiological Condition: Group Overview

F52-SEXUAL-DYSFUNCTION-NOT-DUE

ICD-10-CM Code For Sexual Dysfunction Not Due To A Substance Or Known Physiological Condition: Group Overview

F53-MENTAL-AND-BEHAVIORAL-DISORDERS-ASSOCIATED-WITH-THE-PUERPERIUM

ICD-10-CM Code For Mental And Behavioral Disorders Associated With The Puerperium Not Elsewhere Classified: Group Overview

F54-PSYCHOLOGICAL-AND-BEHAVIORAL-FACTORS

ICD-10-CM Code For Psychological And Behavioral Factors Associated With Disorders Or Diseases Classified Elsewhere: Group Overview

F59-UNSPECIFIED-BEHAVIORAL-SYNDROMES

ICD-10-CM Code For Unspecified Behavioral Syndromes Associated With Physiological Disturbances And Physical Factors: Group Overview

Frequently Asked Questions

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

Published by

Trek Health powers OpenPayer with a leading commercial payer intelligence platform, seamlessly converting fragmented payer data into actionable insights for provider organizations.

ICD-10-CM Code For Abuse Of Non-Psychoactive Substances: Group Overview

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ICD-10-CM F55: Abuse Of Non-Psychoactive Substances Overview

ICD-10-CM Code For Abuse Of Non-Psychoactive Substances: Group Overview

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ICD-10-CM F55: Abuse Of Non-Psychoactive Substances Overview

When to Use

ICD-10-CM Codes

DRG Codes

Typical Clinical Scenarios

Related Codes

Which conditions are included in the ICD-10-CM F55 group?

How are individual diagnosis codes within this group represented?

Why is accurate coding within `F55` important for reimbursement?

Which DRGs are related to the F55 diagnosis group?

What clinical scenarios should be documented when coding an `F55` diagnosis?

References

When to Use

ICD-10-CM Codes

DRG Codes

Typical Clinical Scenarios

Related Codes

Which conditions are included in the ICD-10-CM F55 group?

How are individual diagnosis codes within this group represented?

Why is accurate coding within `F55` important for reimbursement?

Which DRGs are related to the F55 diagnosis group?

What clinical scenarios should be documented when coding an `F55` diagnosis?

References