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    v1.0.28
    OpenPayerBilling CodesOther disorders of glucose regulation and pancreatic internal secretionICD-10-CM e15-nondiabetic-hypoglycemic-coma
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    ICD-10-CM Code For Nondiabetic Hypoglycemic Coma: Group Overview

    The International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) code group E15 includes diagnoses for nondiabetic hypoglycemic coma and related acute hypoglycemic events not caused by diabetes, covering severe hypoglycemia with loss of consciousness and associated neurologic compromise. These ICD-10-CM diagnosis codes are used to document acute metabolic emergencies, capturing clinical severity, neurologic involvement, and complications relevant to this group. Accurate coding within the ICD-10-CM E15 group supports proper claim adjudication.

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    ICD-10-CM E15: Nondiabetic Hypoglycemic Coma Overview

    The ICD-10-CM E15 diagnosis group represents nondiabetic hypoglycemic coma, an acute metabolic condition characterized by severely low blood glucose leading to altered consciousness. These diagnoses target systemic metabolic dysfunction affecting neurologic status and require timely recognition and documentation. Accurate coding matters because it supports proper claim adjudication and reflects the clinical severity for appropriate reimbursement.

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    When to Use

    Use a code from this group when a patient experiences a documented episode of severe hypoglycemia resulting in coma and the episode is not attributable to diabetes mellitus. These codes apply when clinical documentation indicates loss of consciousness from hypoglycemia and the event is the primary reason for care.

    ICD-10-CM Codes

    1 rows

    ICD-10-CM CodeDescription
    E15Nondiabetic hypoglycemic coma

    DRG Codes

    4 rows

    DRG CodeDescription
    640Miscellaneous Disorders of Nutrition, Metabolism, Fluids and Electrolytes with MCC
    641Miscellaneous Disorders of Nutrition, Metabolism, Fluids and Electrolytes without MCC
    791Prematurity with Major Problems
    793Full Term Neonate with Major Problems

    Typical Clinical Scenarios

    • An elderly patient is brought to the emergency department after being found unresponsive at home with a low fingerstick glucose and no history of diabetes or insulin use; initial evaluation excludes ingestion of antidiabetic medications and reveals severe hypoglycemia with altered consciousness requiring intravenous dextrose. A diagnosis from this group is assigned because the patient is in hypoglycemic coma not related to known diabetes. Typical codes: E15
    • A middle-aged patient with a history of advanced liver disease presents with recurrent episodes of early-morning confusion and documented low plasma glucose levels, thought to be due to impaired gluconeogenesis and fasting hypoglycemia; hospital admission is required for monitoring and treatment to prevent progression to loss of consciousness. A code from this group is used to capture the nondiabetic hypoglycemic coma risk/state when metabolic failure leads to severe hypoglycemia. Typical codes: E15
    • A young adult intentionally ingests an oral hypoglycemic agent in a suicide attempt and arrives at the ED obtunded after prolonged hypoglycemia; after stabilization and exclusion of diabetes mellitus, the care team documents profound hypoglycemia with coma attributable to non-diabetic causes (toxic ingestion). The group code is assigned to indicate nondiabetic hypoglycemic coma as the clinical condition. Typical codes: E15

    Related Codes

    E16-OTHER-DISORDERS-OF-PANCREATIC-SECRETION

    ICD-10-CM Code For Other Disorders Of Pancreatic Internal Secretion: Group Overview

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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