Loading...

    Explore
    • Policy Monitoring
    • Live Policy Feed
    • Billing Codes
    • NPI Medicare & Medicaid
    • Healthcare Providers
    • Health Insurance Payers
    • States
    • Service Lines
    • Taxonomy Codes
    Lookup tools
    • Billing Code Lookup
    • CPT Modifier Lookup
    • Provider Taxonomy Code Lookup
    • Healthcare Provider & Facility Lookup
    • Health Insurance Payer Lookup
    • Payer Contact Directory

    Policy & Benchmark Tools

    • Prior Authorization Lookup
    • Coverage Criteria Lookup
    • Timely Filing Lookup
    • Billing Code Reimbursement Rates
    • Payer Comparison Dashboard
    • Facility Comparison Dashboard
    • All tools

    Company

    • About OpenPayer
    • Data Sources
    • Trek Health
    OpenPayerby Trek Health
    LinkedInYouTube

    © 2026 Trek Health. All rights reserved.

    OpenPayer is built and maintained by Trek Health.

    v1.0.28
    OpenPayerBilling CodesCertain disorders involving the immune mechanismICD-10-CM d83-common-variable-immunodeficiency
    Ask Trek AI about this page

    ICD-10-CM Code For Common Variable Immunodeficiency: Group Overview

    The International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) code group D83 includes diagnoses of common variable immunodeficiency and related predominantly antibody deficiencies that present with hypogammaglobulinemia, recurrent infections, and possible autoimmune or granulomatous disease. These ICD-10-CM diagnosis codes are used to document clinical scenarios such as recurrent sinopulmonary infections, severe or persistent hypogammaglobulinemia, and organ-specific complications requiring immunoglobulin replacement or other immune-modulating therapies, capturing disease severity, organ involvement, and clinical complexity relevant to this group. Accurate coding within the ICD-10-CM D83 group supports proper claim adjudication, complete clinical documentation, and appropriate reimbursement.

    Customize your policy alerts

    Sign up for ICD-10-CM Code For Common Variable Immunodeficiency: Group Overview policy alerts

    Get alerted when relevant policies change without checking for updates manually.

    Monitor payer policy activity

    Receive email alerts as soon as relevant payer policies are published or updated.

    ICD-10-CM D83: Common Variable Immunodeficiency Overview

    The diagnoses in this group represent primary antibody deficiencies characterized by low immunoglobulin levels and impaired antibody responses, leading to recurrent infections and increased autoimmune and malignant complications. These conditions target the immune system, particularly B‑cell function and humoral immunity. Accurate coding matters for reimbursement because it documents disease complexity and justifies medically necessary services tied to immune deficiency management.

    Table of contents

    Progress1 / 6

    Explore openpayer tools

    • Billing CodesCPT, HCPCS, DRG & more
    • Reimbursement RatesCommercial vs. Medicare rate reports
    • ProvidersHospitals & facilities
    • PayersPlans & market footprint
    • Taxonomy CodesNUCC specialty codes
    • ModifiersCPT modifiers & usage
    • Prior AuthorizationPA policies by payer & drug
    • Timely FilingFiling deadlines by payer
    • Coverage CriteriaMedical necessity by payer
    • Payer ContactsClaims, PA & appeals contacts
    View all tools

    When to Use

    Use codes from this group when a patient has documented hypogammaglobulinemia with clinical evidence of recurrent or severe infections or when antibody deficiency has been confirmed by laboratory testing. These codes are appropriate for encounters involving evaluation, management, and treatment decisions related to antibody replacement therapy, infection management, or monitoring of immune-related complications.

    ICD-10-CM Codes

    5 rows

    ICD-10-CM CodeDescription
    D83.0Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function
    D83.1Common variable immunodeficiency with predominant immunoregulatory T-cell disorders
    D83.2Common variable immunodeficiency with autoantibodies to B- or T-cells
    D83.8Other common variable immunodeficiencies
    D83.9Common variable immunodeficiency, unspecified

    DRG Codes

    3 rows

    DRG CodeDescription
    814Reticuloendothelial and Immunity Disorders with MCC
    815Reticuloendothelial and Immunity Disorders with CC
    816Reticuloendothelial and Immunity Disorders without CC/MCC

    Typical Clinical Scenarios

    • An adult patient with a years-long history of recurrent sinopulmonary infections (recurrent otitis, sinusitis, and bronchitis) now presents for evaluation of chronic fatigue and progressive bronchiectasis on chest CT. Immunologic testing reveals markedly reduced serum immunoglobulin G and poor vaccine response, confirming a primary antibody deficiency requiring immunoglobulin replacement therapy; a diagnosis from this group is assigned to capture the underlying immunodeficiency driving the infections. Typical codes: D83.9, D83.1
    • A school-aged child is evaluated after multiple severe, unusual infections including pneumonia and recurrent otitis media since infancy; laboratory workup shows low IgG and IgA with impaired specific antibody production and no secondary cause identified. The child is diagnosed with a congenital hypogammaglobulinemia subtype of common variable immunodeficiency to guide long-term immunologic management and prophylactic planning. Typical codes: D83.0, D83.1
    • An adult patient with established antibody deficiency presents to the emergency department with acute bacterial sepsis and a documented splenic abscess as a complication of recurrent encapsulated organism infections. The acute infectious complication is managed emergently while the underlying primary immunodeficiency is coded to explain susceptibility and influence inpatient immunologic support decisions. Typical codes: D83.2, D83.8

    Related Codes

    D80-IMMUNODEFICIENCY-WITH-PREDOMINANTLY-ANTIBODY-DEFECTS

    ICD-10-CM Code For Immunodeficiency With Predominantly Antibody Defects: Group Overview

    D81-COMBINED-IMMUNODEFICIENCIES

    ICD-10-CM Code For Combined Immunodeficiencies: Group Overview

    D82-IMMUNODEFICIENCY-WITH-MAJOR-DEFECTS

    ICD-10-CM Code For Immunodeficiency Associated With Other Major Defects: Group Overview

    D84-OTHER-IMMUNODEFICIENCIES

    ICD-10-CM Code For Other Immunodeficiencies: Group Overview

    D86-SARCOIDOSIS

    ICD-10-CM Code For Sarcoidosis: Group Overview

    D89-OTHER-IMMUNE-MECHANISM-DISORDERS

    ICD-10-CM Code For Other Disorders Involving The Immune Mechanism Not Elsewhere Classified: Group Overview

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
    Published by

    Trek Health powers OpenPayer with a leading commercial payer intelligence platform, seamlessly converting fragmented payer data into actionable insights for provider organizations.

    Trek Health ingests and normalizes Transparency in Coverage data and payer policy updates to give provider organizations a clear view of how commercial reimbursement behaves across markets, payers, and services. Our platform transforms raw payer disclosures into structured intelligence that supports contract evaluation, payer negotiations, and service line strategy. By combining market benchmarks with ongoing policy visibility, Trek helps teams identify variability, risk, and opportunity in commercial reimbursement. The result is faster insight, stronger negotiating positions, and more informed financial decisions.