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    OpenPayerBilling CodesIn situ neoplasmsICD-10-CM d01-carcinoma-in-situ-digestive
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    ICD-10-CM Code For Carcinoma In Situ Of Other And Unspecified Digestive Organs: Group Overview

    The International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) code group D01 includes noninvasive malignant epithelial neoplasms (carcinoma in situ) of other and unspecified digestive organs, covering early-stage lesions confined to the mucosa of digestive tract sites not specified in other D01 subcategories. These ICD-10-CM diagnosis codes are used to document localized, preinvasive neoplastic conditions, capturing lesion anatomic site and neoplastic status relevant to staging and management. Accurate coding within the ICD-10-CM D01 group supports proper claim adjudication, complete clinical documentation, and appropriate reimbursement.

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    ICD-10-CM D01: Carcinoma In Situ Of Other And Unspecified Digestive Organs Overview

    The ICD-10-CM D01 group represents carcinoma in situ lesions arising in digestive organs not classified elsewhere, including unspecified sites within the digestive tract. These codes target early, noninvasive neoplastic changes confined to the epithelium of gastrointestinal organs. Accurate coding is important for clinical documentation, cancer registry reporting, and supporting appropriate reimbursement for diagnostic and treatment services.

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    When to Use

    Use a code from this group when a clinician documents carcinoma in situ of a digestive organ that does not have a more specific D01 subcategory or when the site is unspecified. These codes apply when pathology or clinical assessment confirms a noninvasive epithelial neoplasm confined to the organ mucosa, prior to invasion of deeper tissues.

    ICD-10-CM Codes

    9 rows

    ICD-10-CM CodeDescription
    D01.0Carcinoma in situ of colon
    D01.1Carcinoma in situ of rectosigmoid junction
    D01.2Carcinoma in situ of rectum
    D01.3Carcinoma in situ of anus and anal canal
    D01.40Carcinoma in situ of unspecified part of intestine
    D01.49Carcinoma in situ of other parts of intestine
    D01.5Carcinoma in situ of liver, gallbladder and bile ducts
    D01.7Carcinoma in situ of other specified digestive organs
    D01.9Carcinoma in situ of digestive organ, unspecified

    DRG Codes

    6 rows

    DRG CodeDescription
    374Digestive Malignancy with MCC
    375Digestive Malignancy with CC
    376Digestive Malignancy without CC/MCC
    435Malignancy of Hepatobiliary System or Pancreas with MCC
    436Malignancy of Hepatobiliary System or Pancreas with CC
    437Malignancy of Hepatobiliary System or Pancreas without CC/MCC

    Typical Clinical Scenarios

    • An asymptomatic adult undergoing routine colorectal screening has a colonoscopic biopsy that reveals malignant cells confined to the mucosal epithelium of the colon without invasion of the lamina propria or beyond. The patient presents for follow-up to discuss endoscopic resection options after the pathology report confirms in situ carcinoma limited to the large intestine mucosa; a diagnosis from this group is assigned to indicate carcinoma in situ of the colon. Typical codes: D01.2

    • A middle-aged patient with a history of Barrett esophagus is evaluated for new dysphagia; endoscopy with targeted biopsies demonstrates high-grade dysplastic changes consistent with carcinoma in situ of the esophagus. The encounter is for diagnostic evaluation and management planning because the lesion is confined to the epithelial layer and has not invaded subepithelial tissue, warranting assignment of an in situ esophageal neoplasm code. Typical codes: D01.0

    • An elderly patient with a prior history of resected gastric adenomas presents for surveillance; biopsy of a suspicious gastric mucosal lesion shows carcinoma in situ limited to the stomach lining without invasion. This visit is for postoperative surveillance and local treatment planning for a mucosal neoplasm, and a diagnosis from this group is used to document carcinoma in situ of the stomach. Typical codes: D01.1

    Related Codes

    D00-CARCINOMA-IN-SITU-ORAL-ESOPHAGUS-STOMACH

    ICD-10-CM Code For Carcinoma In Situ Of Oral Cavity, Esophagus And Stomach: Group Overview

    D02-CARCINOMA-IN-SITU-MIDDLE-EAR-RESPIRATORY

    ICD-10-CM Code For Carcinoma In Situ Of Middle Ear And Respiratory System: Group Overview

    D03-MELANOMA-IN-SITU

    ICD-10-CM Code For Melanoma In Situ: Group Overview

    D04-CARCINOMA-IN-SITU-OF-SKIN

    ICD-10-CM Code For Carcinoma In Situ Of Skin: Group Overview

    D05-CARCINOMA-IN-SITU-OF-BREAST

    ICD-10-CM Code For Carcinoma In Situ Of Breast: Group Overview

    D06-CARCINOMA-IN-SITU-OF-CERVIX-UTERI

    ICD-10-CM Code For Carcinoma In Situ Of Cervix Uteri: Group Overview

    D07-CARCINOMA-IN-SITU-GENITAL-ORGANS

    ICD-10-CM Code For Carcinoma In Situ Of Other And Unspecified Genital Organs: Group Overview

    D09-CARCINOMA-IN-SITU-OTHER-UNSPECIFIED-SITES

    ICD-10-CM Code For Carcinoma In Situ Of Other And Unspecified Sites: Group Overview

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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