CPT code 96573 covers photodynamic therapy in which a provider applies a photosensitizing drug to a lesion and exposes the area to a wavelength of light to destroy precancerous cells of the skin and adjacent mucosa. The code is reportable only once per day and applies to procedures performed by a physician or other qualified health care professional. As a targeted, localized therapy for superficial precancerous and early neoplastic lesions, the code has clinical relevance across dermatology and certain otolaryngology or oral mucosal practices.

Key payers in the national coverage landscape include Aetna, Blue Cross Blue Shield, Cigna Health, UnitedHealthcare, and Medicare. Readers will find an overview of clinical context and site-of-service considerations, typical billing and reporting constraints, and where to look for payer-specific coverage and reimbursement policies. The publication also summarizes common modifiers and administrative details when available and notes when input data are incomplete.

This analysis is designed for national audiences seeking a concise reference on the service definition, typical care settings, and payer scope for CPT code 96573, supporting operational, coding, and policy decision-making.