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    v1.0.30
    OpenPayerBilling CodesPostmortem Examination ProceduresCPT cpt-88027-postmortem-pathologic-examination-brain-spinal-cord
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    CPT 88027: Autopsy Technical Exam Including Brain and Spinal Cord

    CPT code 88027 describes the technical components of a postmortem examination in which the provider performs gross and microscopic analysis of a body after death, specifically including evaluation of the brain and spinal cord; service type: postmortem/autopsy pathology technical service; typical site of service: hospital morgue, medical examiner/coroner facility, or pathology laboratory performing autopsy services.

    For related coverage guidance, see recent payer policy updates: General Inflammation Testing, Urine Culture Testing for Bacteria, Biomarkers for Myocardial Infarction and Chronic Heart Failure.

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    Clinical & Coding Specifications

    Clinical Context

    A typical patient scenario involves a decedent brought to a medical examiner's office or hospital pathology department for a full autopsy after an unexpected, unexplained, or medicolegally significant death. The deceased may be an adult found unresponsive at home, a child with sudden unexpected death, or a trauma patient who died after resuscitation efforts. The clinical workflow begins with documentation of identity and circumstances of death, acquisition of consent or legal authorization when required, and external examination. The provider then performs the technical steps of a complete postmortem examination including systematic gross dissection, organ removal, and sampling for microscopic examination; this often includes detailed evaluation of the brain and spinal cord. Ancillary services such as toxicology, microbiology, and radiology (postmortem imaging) may be ordered. The pathology team documents gross findings, submits representative tissue blocks, prepares histologic slides, and generates a final autopsy report that integrates gross and microscopic findings to determine cause and manner of death. Typical sites of service are hospital pathology departments, medical examiner/coroner facilities, and dedicated forensic pathology centers.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    88027The provider performs the technical steps to analyze a body after death, using gross and microscopic examination, including the brain and spinal cord.Primary code describing complete autopsy with brain and spinal cord examination.
    88305Surgical pathology, gross and microscopic examination; tissue, single specimen (e.g., biopsy, polypectomy)Used for specific ancillary organ or tissue biopsies processed separately from autopsy blocks when reported individually.
    88342Immunohistochemistry, each antibody (including controls)Used for immunostains ordered on autopsy tissue for diagnostic clarification (e.g., neuropathologic markers).
    88360Morphometric analysis; manual or computer-assisted, per specimenUsed when additional quantitative morphometry is performed on autopsy tissue.
    87490Infectious agent detection by nucleic acid (e.g., PCR), direct probe techniqueUsed for molecular infectious disease testing on autopsy specimens when indicated.
    76942Ultrasonic guidance for needle placement (eg, biopsy)Used if postmortem image-guided sampling is performed prior to or during the autopsy for targeted tissue collection.

    Related Modifiers

    8 rows

    ModifierDescriptionWhen to Use
    26Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…
    90Modifier ‑90 (Reference/Outside Laboratory) indicates that a laboratory test was performed by an entity other than the treating or reporting provider. The American Medical Association defines…- Use CPT modifier -90 when a laboratory test is performed by an outside/reference laboratory (an entity other than the treating or reporting physician or qualified professional) and the claim needs…
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    23Modifier -23 (Unusual Anesthesia) is used on anesthesia service CPT codes when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia…- Use modifier -23 only on anesthesia CPT codes (00100–01999) when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia because of…

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    207P00000X
    207L00000X
    207K00000X
    2084F0202X
    213ER0200X
    193200000X
    2255A2300X
    347D00000X

    Related Payer Policy Updates

    Specialty: Laboratory/Pathology1 / 2

    10 rows

    PolicyPayerEffective Date
    General Inflammation TestingOscar Health2027-01-01
    Urine Culture Testing for BacteriaOscar Health2027-01-01
    Biomarkers for Myocardial Infarction and Chronic Heart FailureOscar Health2027-01-01
    Policy Regarding Outpatient Definitive Drug TestingMolina Healthcare2027-01-01
    Serum Testing for Evidence of Mild Traumatic Brain InjuryHealthfirst2026-11-01
    Respiratory Viral PanelsProvidence Health Plan2026-10-01
    Serum Iron StudiesProvidence Health Plan2026-10-01
    Prothrombin Time (PT)Providence Health Plan2026-10-01
    Partial Thromboplastin Time (PTT)Providence Health Plan2026-10-01
    Respiratory Viral PanelsProvidence Health Plan2026-10-01

    Related Codes

    CPT-88000-POSTMORTEM-GROSS-EXAMINATION-EXTERNAL-ONLY

    CPT 88000: Postmortem External Examination

    CPT-88005-GROSS-POSTMORTEM-EXAMINATION-WITH-BRAIN

    CPT 88005: Gross Postmortem Examination Including Brain

    CPT-88007-POSTMORTEM-GROSS-EXAMINATION-BRAIN-SPINAL-CORD

    CPT 88007: Gross Autopsy Examination Including Brain and Spinal Cord

    CPT-88012-INFANT-POSTMORTEM-GROSS-ANALYSIS-BRAIN-INCLUDED

    CPT 88012: Gross Postmortem Examination of Infant, Including Brain

    CPT-88014-STILLBORN-NEWBORN-GROSS-ANALYSIS-INCLUDING-BRAIN

    CPT 88014: Gross Analysis of Stillborn or Newborn Including Brain

    CPT-88016-GROSS-ANALYSIS-MACERATED-STILLBORN

    CPT 88016: Gross Examination of Macerated Stillborn

    CPT-88020-POSTMORTEM-TECHNICAL-GROSS-AND-MICROSCOPIC-EXAM-EXCLUDING-CNS

    CPT 88020: Autopsy, External and Internal Examination Excluding CNS

    CPT-88025-AUTOPSY-WITH-BRAIN-EXAMINATION-TECHNICAL

    CPT 88025: Autopsy with Gross and Microscopic Examination Including Brain

    CPT-88028-INFANT-POSTMORTEM-TECHNICAL-AUTOPSY

    CPT 88028: Technical Infant Postmortem Examination

    CPT-88029-NEONATAL-STILLBORN-POSTMORTEM-PATHOLOGY-INCLUDING-BRAIN

    CPT 88029: Postmortem Exam of Stillborn/Newborn, Gross and Microscopic

    Showing 1–10 of 15

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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