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    v1.0.30
    OpenPayerBilling CodesPostmortem Examination ProceduresCPT cpt-88005-gross-postmortem-examination-with-brain
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    CPT 88005: Gross Postmortem Examination Including Brain

    CPT code 88005 describes a gross postmortem examination (autopsy) including inspection of the brain, representing a full-body external and internal examination performed after death; the service type is a postmortem autopsy/gross examination and the typical site of service is a morgue, medical examiner's facility, or hospital pathology/autopsy suite where a pathologist assesses external features and performs dissection for diagnostic, medicolegal, or certification purposes.

    For related coverage guidance, see recent payer policy updates: General Inflammation Testing, Urine Culture Testing for Bacteria, Biomarkers for Myocardial Infarction and Chronic Heart Failure.

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    Clinical & Coding Specifications

    Clinical Context

    A forensic pathologist or autopsy surgeon performs a complete gross autopsy including removal and examination of the brain to determine cause and manner of death. Typical scenarios include unexpected, unexplained, or medicolegal deaths brought by law enforcement or medical examiners, inpatient deaths with unclear etiology, or deaths requiring diagnostic clarification for family or insurance. The workflow begins with receipt of the decedent and legal authorization, review of medical records and scene findings, external examination, evisceration and internal gross examination of thoracic and abdominal organs, removal of the brain via craniotomy for gross inspection, documentation of findings with photos and dictation, selection of tissues for microscopic or ancillary testing, and completion of the autopsy report. Specimens may be sent for histology, toxicology, microbiology, or neuropathology. Typical site of service is a hospital mortuary, medical examiner/coroner facility, or dedicated pathology autopsy suite. Patient scenario example: a 45-year-old male found unresponsive at home with no prior history; death is unwitnessed and cause unknown, requiring medicolegal autopsy including brain examination to evaluate for intracranial hemorrhage, infarct, or toxic-metabolic processes.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    88005Gross analysis of a body after death, including examining the brainPrimary procedure: complete gross autopsy with brain examination
    88305Level IV surgical pathology, gross and microscopic examinationUsed when representative tissues from the autopsy are submitted for microscopic histopathology
    88342Immunohistochemistry, per specimen; first stainMay be used for special stains on brain or other tissues identified during autopsy
    88181Cytopathology, postmortem tissue (e.g., body fluids)When cytologic evaluation of postmortem fluids or tissues is required
    89300Forensic toxicology, qualitativeCommonly paired when toxicology testing is ordered as part of medicolegal investigation

    Related Modifiers

    10 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    26Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    54Modifier ‑54 (“Surgical care only”) is appended to a CPT surgical procedure when the reporting surgeon performs the intraoperative (surgical) component but does not furnish the preoperative and/or…- Use modifier -54 when the reporting surgeon provided only the intraoperative (surgical) component of a procedure and preoperative and/or postoperative management has been or will be provided by…
    55Modifier –55 indicates the billing provider furnished only postoperative management for a procedure that has a global surgical period. According to AAPC, this modifier is appended to the same CPT…- Use modifier -55 when billing the same CPT surgical code that has a 10- or 90-day global period and you, as a provider other than the original surgeon, furnished ONLY postoperative management (no…
    56Modifier ‑56 indicates the reporting provider furnished only the preoperative management for a surgical procedure and did not perform the intraoperative or postoperative care. It is used in…- Use Modifier -56 when a provider performs only the preoperative management in a split‑care situation (one physician manages preop care while a different physician performs the intraoperative…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…
    90Modifier ‑90 (Reference/Outside Laboratory) indicates that a laboratory test was performed by an entity other than the treating or reporting provider. The American Medical Association defines…- Use CPT modifier -90 when a laboratory test is performed by an outside/reference laboratory (an entity other than the treating or reporting physician or qualified professional) and the claim needs…

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    207L00000X
    2080P0006X
    207R00000X
    363A00000X
    125Q00000X
    207RM1200X
    207XP3100X
    122400000X

    Related ICD-10-CM Codes

    24 rows

    ICD-10-CM CodeDescription
    A40.9Streptococcal sepsis, unspecified
    A41.9Sepsis, unspecified organism
    C34.90Malignant neoplasm of unspecified part of unspecified bronchus or lung
    D65Disseminated intravascular coagulation [defibrination syndrome]
    F03.90Unspecified dementia, unspecified severity, without behavioral disturbance, psychotic disturbance, mood disturbance, and anxiety
    G40.909Epilepsy, unspecified, not intractable, without status epilepticus
    G45.9Transient cerebral ischemic attack, unspecified
    G93.1Anoxic brain damage, not elsewhere classified
    I21.3ST elevation (STEMI) myocardial infarction of unspecified site
    I46.9Cardiac arrest, cause unspecified

    Showing 1–10 of 24

    Related Payer Policy Updates

    Specialty: Laboratory/Pathology1 / 2

    10 rows

    PolicyPayerEffective Date
    General Inflammation TestingOscar Health2027-01-01
    Urine Culture Testing for BacteriaOscar Health2027-01-01
    Biomarkers for Myocardial Infarction and Chronic Heart FailureOscar Health2027-01-01
    Policy Regarding Outpatient Definitive Drug TestingMolina Healthcare2027-01-01
    Serum Testing for Evidence of Mild Traumatic Brain InjuryHealthfirst2026-11-01
    Respiratory Viral PanelsProvidence Health Plan2026-10-01
    Serum Iron StudiesProvidence Health Plan2026-10-01
    Prothrombin Time (PT)Providence Health Plan2026-10-01
    Partial Thromboplastin Time (PTT)Providence Health Plan2026-10-01
    Respiratory Viral PanelsProvidence Health Plan2026-10-01

    Related Codes

    CPT-88000-POSTMORTEM-GROSS-EXAMINATION-EXTERNAL-ONLY

    CPT 88000: Postmortem External Examination

    CPT-88007-POSTMORTEM-GROSS-EXAMINATION-BRAIN-SPINAL-CORD

    CPT 88007: Gross Autopsy Examination Including Brain and Spinal Cord

    CPT-88012-INFANT-POSTMORTEM-GROSS-ANALYSIS-BRAIN-INCLUDED

    CPT 88012: Gross Postmortem Examination of Infant, Including Brain

    CPT-88014-STILLBORN-NEWBORN-GROSS-ANALYSIS-INCLUDING-BRAIN

    CPT 88014: Gross Analysis of Stillborn or Newborn Including Brain

    CPT-88016-GROSS-ANALYSIS-MACERATED-STILLBORN

    CPT 88016: Gross Examination of Macerated Stillborn

    CPT-88020-POSTMORTEM-TECHNICAL-GROSS-AND-MICROSCOPIC-EXAM-EXCLUDING-CNS

    CPT 88020: Autopsy, External and Internal Examination Excluding CNS

    CPT-88025-AUTOPSY-WITH-BRAIN-EXAMINATION-TECHNICAL

    CPT 88025: Autopsy with Gross and Microscopic Examination Including Brain

    CPT-88027-POSTMORTEM-PATHOLOGIC-EXAMINATION-BRAIN-SPINAL-CORD

    CPT 88027: Autopsy Technical Exam Including Brain and Spinal Cord

    CPT-88028-INFANT-POSTMORTEM-TECHNICAL-AUTOPSY

    CPT 88028: Technical Infant Postmortem Examination

    CPT-88029-NEONATAL-STILLBORN-POSTMORTEM-PATHOLOGY-INCLUDING-BRAIN

    CPT 88029: Postmortem Exam of Stillborn/Newborn, Gross and Microscopic

    Showing 1–10 of 15

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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