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    v1.0.28
    OpenPayerBilling CodesChemistry ProceduresCPT cpt-82570-non-blood-creatinine-assay
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    CPT 82570: Creatinine, non-blood specimen measurement

    CPT code 82570 reports a laboratory quantitative measurement of creatinine in a patient specimen other than blood, commonly performed on urine to assess renal function or creatinine clearance; this service is a clinical chemistry laboratory test typically provided in clinical laboratory or outpatient specimen collection settings and documented as a discrete lab result for diagnostic evaluation.

    For related coverage guidance, see recent payer policy updates: Salivary Hormone Testing, Parathyroid Hormone, Phosphorus, Calcium, and Magnesium Testing, Bone Turnover Markers Testing.

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    Table of contents

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    Clinical & Coding Specifications

    Clinical Context

    A 62-year-old male with a history of chronic kidney disease stage 3 and recurrent urinary tract infections presents to the ambulatory laboratory after a primary care visit. The clinician orders a urine creatinine measurement to assess renal handling of creatinine and to assist with interpretation of urine protein or drug urine concentrations. A urine sample is collected in the clinic restroom, labeled, and sent to the hospital clinical chemistry laboratory. The laboratory analyst performs assay 82570 to quantify creatinine concentration in the patient’s non-blood specimen (urine). Results are reported to the ordering provider and integrated into the electronic medical record to guide further evaluation of kidney function and urine concentration-related interpretations.

    Related CPT Codes

    • Related CPT procedures commonly performed with 82570 in clinical workflows.
    CPT CodeDescriptionRelationship to This Procedure
    81002Urinalysis, by dipstick or tablet reagent; non-automated, with microscopyOften performed as an initial screen before urine creatinine quantification to assess concentration and presence of blood or infection.
    82043Creatinine; blood, quantitativeSerum creatinine measurement commonly ordered alongside urine creatinine to evaluate renal function and calculate creatinine clearance when paired with urine creatinine.
    84132Creatinine; urine, quantitativeClosely related assay; this urine creatinine quantitative code may be used for specific reporting contexts depending on payer rules and specimen type.
    82000Assay of urine other than by dipstick; chemical (e.g., glucose)Other urine chemistry tests frequently ordered concurrently to assess metabolic or renal-related abnormalities.
    82570Creatinine; other than bloodPrimary code for reporting the urine creatinine measurement performed by the laboratory.

    Related Modifiers

    6 rows

    ModifierDescriptionWhen to Use
    26Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
    90Modifier ‑90 (Reference/Outside Laboratory) indicates that a laboratory test was performed by an entity other than the treating or reporting provider. The American Medical Association defines…- Use CPT modifier -90 when a laboratory test is performed by an outside/reference laboratory (an entity other than the treating or reporting physician or qualified professional) and the claim needs…
    91Modifier 91 — “Repeat Clinical Diagnostic Laboratory Test” — is appended when the exact same CPT laboratory test is performed more than once for the same patient on the same day because serial,…- Use modifier 91 when the exact same CPT laboratory test is performed more than once on the same patient on the same date because serial or repeated testing is medically necessary to monitor…
    59Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
    76Modifier -76, Repeat Procedure or Service by Same Physician or Other Qualified Health Care Professional, is appended when the same provider performs an identical, medically necessary procedure or…- Use modifier -76 when the same physician or other qualified health care professional performs an identical procedure or service a second (or subsequent) time on the same date of service and the…
    77Modifier 77 indicates that a previously performed procedure or service was legitimately repeated by a different physician or other qualified health care professional. The AMA’s CPT definition…- Use modifier 77 when a basic procedure or service already performed is repeated by a different physician or other qualified health care professional (for example, a second provider independently…

    Related Provider Taxonomies

    8 rows

    Taxonomy CodeSpecialtyNotes
    208D00000XGeneral Practice PhysicianA physician who specializes in the general practice of diagnosing, treating, and managing patients with a variety of illnesses and conditions.
    207Q00000XFamily Medicine PhysicianFamily Medicine is the medical specialty which is concerned with the total health care of the individual and the family. It is the specialty in breadt…
    207L00000XAnesthesiology PhysicianAn anesthesiologist is trained to provide pain relief and maintenance, or restoration, of a stable condition during and immediately following an opera…
    207Y00000XOtolaryngology PhysicianAn otolaryngologist-head and neck surgeon provides comprehensive medical and surgical care for patients with diseases and disorders that affect the ea…
    213ER0200XRadiology PodiatristPodiatric Medicine & Surgery Service Providers · Podiatrist
    207VX0000XObstetrics PhysicianA physician who specializes in diagnosis, treatment, and management of patients with obstetric conditions.
    347D00000XTrainAn organization or business licensed to provide passenger train service, including light rail, subway, and traditional services.
    246ZE0600XElectroneurodiagnostic Specialist/TechnologistTechnologists, Technicians & Other Technical Service Providers · Specialist/Technologist, Other

    Related ICD-10-CM Codes

    26 rows

    ICD-10-CM CodeDescription
    B20Human immunodeficiency virus [HIV] disease
    E11.22Type 2 diabetes mellitus with diabetic chronic kidney disease
    E11.29Type 2 diabetes mellitus with other diabetic kidney complication
    E87.1Hypo-osmolality and hyponatremia
    G60.9Hereditary and idiopathic neuropathy, unspecified
    I12.9Hypertensive chronic kidney disease with stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease
    I13.0Hypertensive heart and chronic kidney disease with heart failure and stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease
    I13.10Hypertensive heart and chronic kidney disease without heart failure, with stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease
    K74.60Unspecified cirrhosis of liver
    N10Acute pyelonephritis

    Showing 1–10 of 26

    Related Payer Policy Updates

    Specialty: Endocrinology1 / 3

    10 rows

    PolicyPayerEffective Date
    Salivary Hormone TestingOscar Health2026-10-01
    Parathyroid Hormone, Phosphorus, Calcium, and Magnesium TestingOscar Health2026-10-01
    Bone Turnover Markers TestingOscar Health2026-10-01
    Testosterone — Coverage Criteria for Measurement and MonitoringOscar Health2026-10-01
    Diabetes Mellitus Testing — Coverage CriteriaOscar Health2026-10-01
    Thyroid Disease TestingOscar Health2026-10-01
    Thyroid Disease Testingblue cross blue shield - louisiana2026-09-15
    Thyroid Disease TestingBlue Cross Blue Shield - New Mexico2026-09-04
    Parathyroid Hormone, Phosphorous, Calcium and Magnesium TestingBlue Cross Blue Shield - New Mexico2026-09-04
    Testosterone laboratory testing and managementPremera Bluecross2026-09-04

    Related Codes

    CPT-82009-KETONE-BODIES-QUALITATIVE-TEST

    CPT 82009: Qualitative Ketone Bodies Test

    CPT-82010-QUANTITATIVE-KETONE-BODIES-ASSAY-SERUM-PLASMA

    CPT 82010: Quantitative Ketone Bodies in Serum or Plasma

    CPT-82013-ACETYLCHOLINESTERASE-QUANTITATIVE-ASSAY

    CPT 82013: Quantitative Acetylcholinesterase (Acetylhydrolase) Assay

    CPT-82016-QUALITATIVE-ACYLCARNITINES-METABOLIC-SCREEN

    CPT 82016: Qualitative Acylcarnitines, Plasma/Serum/Urine

    CPT-82017-QUANTITATIVE-ACYLCARNITINE-ANALYSIS

    CPT 82017: Quantitative Acylcarnitine Analysis

    CPT-82024-QUANTITATIVE-CORTICOTROPIN-ACTH-ASSAY

    CPT 82024: Adrenocorticotropic Hormone (ACTH) Quantitative Assay

    CPT-82030-QUANTITATIVE-CAMP-PLASMA-URINE-ASSAY

    CPT 82030: Quantitative cyclic AMP assay on plasma or urine

    CPT-82040-QUANTITATIVE-ALBUMIN-MEASUREMENT

    CPT 82040: Quantitative Albumin Measurement

    CPT-82042-QUANTITATIVE-ALBUMIN-NONBLOOD-FLUID

    CPT 82042: Albumin Quantitation in Non-Blood Body Fluid

    CPT-82043-URINE-ALBUMIN-QUANTITATION-KIDNEY-DISEASE

    CPT 82043: Urine Albumin Quantitative Assay

    Showing 1–10 of 411

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    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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