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CPT 82340: Quantitative Urine Calcium, Timed Specimen

CPT code 82340 denotes the technical laboratory assay for quantitative calcium measurement in a timed urine specimen. Nationally, this test supports diagnosis and management of disorders of calcium metabolism, evaluation of nephrolithiasis risk, and monitoring of metabolic treatment plans. It is commonly ordered by outpatient clinics, endocrinology and nephrology practices, and hospitals that collect timed urine specimens and send them to clinical laboratories.

Key payers included in the coverage context are Aetna, Blue Cross Blue Shield, Cigna Health, UnitedHealthcare, and Medicare. Readers will find a concise view of what CPT code 82340 represents, typical clinical contexts for use, and the kinds of benchmarks and policy considerations that influence lab billing and coverage nationally. The publication provides a clinical and billing primer: service description, typical site of service, common modifiers (listed separately), and guidance on where to find additional billing details. Data not available in the input is noted where applicable.

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Billing Code Overview

CPT code 82340 describes a laboratory service in which a lab analyst performs the technical assay to determine the quantitative calcium concentration in a timed urine specimen. The procedure measures total urinary calcium over a specified collection interval to aid in evaluation of calcium metabolism, kidney stone risk, hypercalciuria, or related metabolic disorders.

Service type: Quantitative urine biochemical analysis (laboratory test)
Typical site of service: Clinical laboratory or hospital laboratory performing analytic testing on a collected timed urine specimen

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CPT 82340: Quantitative Urine Calcium, Timed Specimen

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Billing Code Overview

Service type: Quantitative urine biochemical analysis (laboratory test)
Typical site of service: Clinical laboratory or hospital laboratory performing analytic testing on a collected timed urine specimen

Clinical & Coding Specifications

Clinical Context

A typical patient is an adult referred for evaluation of hypercalcemia symptoms or metabolic bone disease. The clinician orders a timed urine calcium collection (usually 24-hour) to quantify urinary calcium excretion and help distinguish causes such as primary hyperparathyroidism, familial hypocalciuric hypercalcemia, vitamin D intoxication, or renal calcium wasting. The patient receives written collection instructions, collects all urine over the specified interval into a provided container with preservative as indicated, and returns the specimen to the outpatient laboratory or hospital lab. In the laboratory, a histotechnologist or clinical laboratory scientist performs the technical analysis described by CPT 82340 to determine the quantitative calcium concentration in the timed urine specimen. Results are reported to the ordering provider for interpretation alongside serum calcium, parathyroid hormone, vitamin D levels, and clinical findings. Typical sites of service include hospital outpatient laboratories, independent clinical laboratories, and ambulatory clinic labs performing specimen receipt and analysis.

Coding Specifications

Modifier	Description	When to Use
`26`	Professional component	Use when billing only the professional interpretation component if applicable (rare for automated lab analytes).
`TC`	Technical component	Use when billing only the technical component of the laboratory test (common when facility bills the performative analysis).
`90`	Reference lab	Use when the test is performed by an outside (reference) laboratory on behalf of the ordering laboratory.
`91`	Repeat clinical diagnostic laboratory test	Use when a repeat test on the same day is performed for confirmation or quality issues.
`52`	Reduced services	Use when the test was partially reduced or not completed as originally intended.
`53`	Discontinued service	Use when collection or analysis was started but discontinued for clinical or technical reasons.
`59`	Distinct procedural service	Use to indicate a distinct lab service when bundling edits might apply and the service is separate from other procedures on the same day.
`22`	Increased procedural services	Use when there is a significant, separately identifiable increase in complexity of the laboratory procedure requiring additional resources.
`78`	Return to operating/procedure room for related procedure	Not typically used for routine lab tests; included for completeness in cases of intra-procedural specimens tied to a procedure.
`80`	Assistant surgeon	Not applicable to this lab code except when documentation requires an assistant for specimen acquisition during a procedure.
`QW`	CLIA-waived test	Use when the particular method is CLIA-waived; rarely applicable to quantitative urine calcium measurements.
`QX`	PA or NP billing for qualifying services	Use when a physician assistant bills the technical component under the PA's NPI where applicable.
`QY`	Certified nurse-midwife billing	Use when performed and billed under a certified nurse-midwife for qualifying services.

Taxonomy Code	Specialty	Notes
261QM0800X	Clinical Laboratory	Clinical laboratory scientists and technicians who perform and supervise laboratory testing.
207L00000X	Pathology	Pathologists who oversee laboratory operations and interpret complex lab results.
363LP0800X	Chemistry Laboratory	Specialists in clinical chemistry performing quantitative biochemical assays.
207K00000X	Family Medicine	Ordering providers who commonly request urine calcium testing for metabolic evaluation.
207R00000X	Internal Medicine	Ordering providers managing disorders of calcium metabolism and coordinating diagnostic testing.

Related Diagnoses

ICD-10 Code	Description	Clinical Relevance
`E21.0`	Primary hyperparathyroidism	Elevated PTH can cause hypercalcemia with increased urinary calcium excretion; 24-hour urine calcium helps evaluate renal calcium loss.
`E83.52`	Hypercalcemia	Direct clinical indication for measurement of urine calcium to assess cause and renal handling.
`E83.59`	Other disorders of calcium metabolism	Used when specific calcium metabolism disorders are suspected and quantitative urine calcium aids diagnosis.
`N25.9`	Disorder resulting from impaired renal tubular function, unspecified	Renal causes of abnormal calcium handling may prompt timed urine calcium testing.
`M80.00XA`	Age-related osteoporosis with current pathological fracture, unspecified site, initial encounter	Workup for metabolic bone disease often includes calcium studies including urine calcium to assess calcium balance.

Related CPT Codes

CPT Code	Description	Relationship to This Procedure
`82330`	Calcium; serum, total	Serum total calcium is commonly ordered alongside urine calcium to compare serum and urinary calcium handling.
`83520`	Creatinine; urine	Urine creatinine is often measured on timed urine collections to validate collection completeness and calculate ratios.
`83970`	Parathyroid hormone (PTH)	PTH testing is commonly performed concurrently to evaluate causes of altered calcium metabolism.
`83655`	Vitamin D; 25-hydroxy	Measurement of vitamin D status is frequently ordered with urinary calcium to assess causes of hypercalcemia or bone disease.
`81002`	Urinalysis, non-automated without microscopy	A screening urinalysis may be performed on the specimen to document appearance and exclude gross abnormalities prior to quantitative testing.

CPT 82009: Qualitative Ketone Bodies Test

CPT-82010-QUANTITATIVE-KETONE-BODIES-ASSAY-SERUM-PLASMA

CPT 82010: Quantitative Ketone Bodies Assay, Serum or Plasma

CPT-82013-ACETYLCHOLINESTERASE-QUANTITATIVE-ASSAY

CPT 82013: Quantitative Acetylcholinesterase (Acetylhydrolase) Assay

CPT-82016-QUALITATIVE-ACYLCARNITINES-METABOLIC-SCREEN

CPT 82016: Qualitative Acylcarnitines Metabolic Screen

CPT-82017-QUANTITATIVE-ACYLCARNITINE-ANALYSIS

CPT 82017: Quantitative Acylcarnitine Analysis

CPT-82024-QUANTITATIVE-CORTICOTROPIN-ACTH-ASSAY

CPT 82024: Quantitative Corticotropin (ACTH) Assay

CPT-82030-QUANTITATIVE-CAMP-PLASMA-URINE-ASSAY

CPT 82030: Quantitative cAMP Assay on Plasma or Urine

CPT-82040-QUANTITATIVE-ALBUMIN-MEASUREMENT

CPT 82040: Quantitative Albumin Measurement in Blood

CPT-82042-QUANTITATIVE-ALBUMIN-NONBLOOD-FLUID

CPT 82042: Quantitative Albumin in Non-Blood Body Fluid

CPT-82043-URINE-ALBUMIN-QUANTITATION-KIDNEY-DISEASE

CPT 82043: Urine Albumin Quantitation for Kidney Disease

Showing 1–10 of 411

Frequently Asked Questions

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

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Trek Health ingests and normalizes Transparency in Coverage data and payer policy updates to give provider organizations a clear view of how commercial reimbursement behaves across markets, payers, and services. Our platform transforms raw payer disclosures into structured intelligence that supports contract evaluation, payer negotiations, and service line strategy. By combining market benchmarks with ongoing policy visibility, Trek helps teams identify variability, risk, and opportunity in commercial reimbursement. The result is faster insight, stronger negotiating positions, and more informed financial decisions.

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Clinical & Coding Specifications

Clinical Context

Coding Specifications

Modifier	Description	When to Use
`26`	Professional component	Use when billing only the professional interpretation component if applicable (rare for automated lab analytes).
`TC`	Technical component	Use when billing only the technical component of the laboratory test (common when facility bills the performative analysis).
`90`	Reference lab	Use when the test is performed by an outside (reference) laboratory on behalf of the ordering laboratory.
`91`	Repeat clinical diagnostic laboratory test	Use when a repeat test on the same day is performed for confirmation or quality issues.
`52`	Reduced services	Use when the test was partially reduced or not completed as originally intended.
`53`	Discontinued service	Use when collection or analysis was started but discontinued for clinical or technical reasons.
`59`	Distinct procedural service	Use to indicate a distinct lab service when bundling edits might apply and the service is separate from other procedures on the same day.
`22`	Increased procedural services	Use when there is a significant, separately identifiable increase in complexity of the laboratory procedure requiring additional resources.
`78`	Return to operating/procedure room for related procedure	Not typically used for routine lab tests; included for completeness in cases of intra-procedural specimens tied to a procedure.
`80`	Assistant surgeon	Not applicable to this lab code except when documentation requires an assistant for specimen acquisition during a procedure.
`QW`	CLIA-waived test	Use when the particular method is CLIA-waived; rarely applicable to quantitative urine calcium measurements.
`QX`	PA or NP billing for qualifying services	Use when a physician assistant bills the technical component under the PA's NPI where applicable.
`QY`	Certified nurse-midwife billing	Use when performed and billed under a certified nurse-midwife for qualifying services.

Taxonomy Code	Specialty	Notes
261QM0800X	Clinical Laboratory	Clinical laboratory scientists and technicians who perform and supervise laboratory testing.
207L00000X	Pathology	Pathologists who oversee laboratory operations and interpret complex lab results.
363LP0800X	Chemistry Laboratory	Specialists in clinical chemistry performing quantitative biochemical assays.
207K00000X	Family Medicine	Ordering providers who commonly request urine calcium testing for metabolic evaluation.
207R00000X	Internal Medicine	Ordering providers managing disorders of calcium metabolism and coordinating diagnostic testing.

Related Diagnoses

ICD-10 Code	Description	Clinical Relevance
`E21.0`	Primary hyperparathyroidism	Elevated PTH can cause hypercalcemia with increased urinary calcium excretion; 24-hour urine calcium helps evaluate renal calcium loss.
`E83.52`	Hypercalcemia	Direct clinical indication for measurement of urine calcium to assess cause and renal handling.
`E83.59`	Other disorders of calcium metabolism	Used when specific calcium metabolism disorders are suspected and quantitative urine calcium aids diagnosis.
`N25.9`	Disorder resulting from impaired renal tubular function, unspecified	Renal causes of abnormal calcium handling may prompt timed urine calcium testing.
`M80.00XA`	Age-related osteoporosis with current pathological fracture, unspecified site, initial encounter	Workup for metabolic bone disease often includes calcium studies including urine calcium to assess calcium balance.

Related CPT Codes

CPT Code	Description	Relationship to This Procedure
`82330`	Calcium; serum, total	Serum total calcium is commonly ordered alongside urine calcium to compare serum and urinary calcium handling.
`83520`	Creatinine; urine	Urine creatinine is often measured on timed urine collections to validate collection completeness and calculate ratios.
`83970`	Parathyroid hormone (PTH)	PTH testing is commonly performed concurrently to evaluate causes of altered calcium metabolism.
`83655`	Vitamin D; 25-hydroxy	Measurement of vitamin D status is frequently ordered with urinary calcium to assess causes of hypercalcemia or bone disease.
`81002`	Urinalysis, non-automated without microscopy	A screening urinalysis may be performed on the specimen to document appearance and exclude gross abnormalities prior to quantitative testing.

CPT 82009: Qualitative Ketone Bodies Test

CPT-82010-QUANTITATIVE-KETONE-BODIES-ASSAY-SERUM-PLASMA

CPT 82010: Quantitative Ketone Bodies Assay, Serum or Plasma

CPT-82013-ACETYLCHOLINESTERASE-QUANTITATIVE-ASSAY

CPT 82013: Quantitative Acetylcholinesterase (Acetylhydrolase) Assay

CPT-82016-QUALITATIVE-ACYLCARNITINES-METABOLIC-SCREEN

CPT 82016: Qualitative Acylcarnitines Metabolic Screen

CPT-82017-QUANTITATIVE-ACYLCARNITINE-ANALYSIS

CPT 82017: Quantitative Acylcarnitine Analysis

CPT-82024-QUANTITATIVE-CORTICOTROPIN-ACTH-ASSAY

CPT 82024: Quantitative Corticotropin (ACTH) Assay

CPT-82030-QUANTITATIVE-CAMP-PLASMA-URINE-ASSAY

CPT 82030: Quantitative cAMP Assay on Plasma or Urine

CPT-82040-QUANTITATIVE-ALBUMIN-MEASUREMENT

CPT 82040: Quantitative Albumin Measurement in Blood

CPT-82042-QUANTITATIVE-ALBUMIN-NONBLOOD-FLUID

CPT 82042: Quantitative Albumin in Non-Blood Body Fluid

CPT-82043-URINE-ALBUMIN-QUANTITATION-KIDNEY-DISEASE

CPT 82043: Urine Albumin Quantitation for Kidney Disease

Showing 1–10 of 411

Frequently Asked Questions

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

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CPT 82340: Quantitative Urine Calcium, Timed Specimen

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Billing Code Overview

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CPT 82340: Quantitative Urine Calcium, Timed Specimen

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Billing Code Overview

Clinical & Coding Specifications

Clinical Context

Coding Specifications

Related Diagnoses

Related CPT Codes

Related Codes

References

Clinical & Coding Specifications

Clinical Context

Coding Specifications

Related Diagnoses

Related CPT Codes

Related Codes

References

CPT 82340: Quantitative Urine Calcium, Timed Specimen

Sign up for cpt 82340 policy alerts

Billing Code Overview

CPT 82340: Quantitative Urine Calcium, Timed Specimen

Sign up for cpt 82340 policy alerts

Billing Code Overview

Clinical & Coding Specifications

Clinical Context

Coding Specifications

Related Diagnoses

Related CPT Codes

Related Codes

What does CPT 82340 represent and where is this service typically performed?

Which billing modifiers are commonly used with CPT 82340 and when are they applied?

In what clinical contexts is a timed urine calcium (CPT 82340) typically ordered?

What other laboratory tests are commonly ordered with CPT 82340?

Which payers commonly cover CPT 82340 and where can I find reimbursement details?

References

Clinical & Coding Specifications

Clinical Context

Coding Specifications

Related Diagnoses

Related CPT Codes

Related Codes

What does CPT 82340 represent and where is this service typically performed?

Which billing modifiers are commonly used with CPT 82340 and when are they applied?

In what clinical contexts is a timed urine calcium (CPT 82340) typically ordered?

What other laboratory tests are commonly ordered with CPT 82340?

Which payers commonly cover CPT 82340 and where can I find reimbursement details?

References