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CPT 83615: Lactate Dehydrogenase (LDH) Measurement, Serum
CPT code 83615 identifies a laboratory assay measuring lactate dehydrogenase (LDH) activity, usually in serum. LDH testing is a widely used clinical chemistry test to help detect tissue injury, hemolysis, and certain disease processes; its broad clinical utility makes it a commonly billed laboratory procedure across inpatient and outpatient settings. Nationally, LDH measurement supports diagnostic workflows in hospitals, outpatient laboratories, and emergency departments and influences downstream clinical decision-making.
Key payers covered include Aetna, Blue Cross Blue Shield, Cigna Health, UnitedHealthcare, and Medicare. The analysis addresses payer coverage norms and common billing practices for lab enzyme assays under these major payers.
Readers will learn the clinical context of the test, typical sites of service, and what is reported for this CPT code. The publication provides benchmarks for utilization and reimbursement where available, highlights relevant policy updates affecting lab billing, and explains coding considerations for laboratories and billing staff. Data not available in the input will be identified explicitly in sections that require it.
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Billing Code Overview
CPT code 83615 measures lactate dehydrogenase (LDH) activity, typically performed on a serum sample. LDH is an enzyme present in many tissues — notably the liver, kidney, heart, and red blood cells — and its level is used as a nonspecific marker of tissue damage or hemolysis.
Service type: Clinical chemistry/serum enzyme assay
Typical site of service: Clinical laboratory or hospital laboratory