CPT code 80327 identifies a laboratory toxicology assay that measures or detects one or two anabolic steroids in a patient specimen. This test is used in clinical and forensic settings to identify use or exposure to synthetic androgenic agents and can inform clinical management, occupational testing, sports medicine, and compliance monitoring. Nationally, accurate coding for this specialized laboratory service affects claim processing, clinical documentation, and surveillance of performance and misuse trends.

Key payers in this analysis include Aetna, Blue Cross Blue Shield, Cigna Health, UnitedHealthcare, and Medicare. Readers will find a concise explanation of what the code represents, typical sites of service, and the clinical context for ordering this assay. The publication provides benchmarks and payer coverage context where available, notes common billing modifiers, and highlights coding considerations relevant to laboratories and billing professionals.

The piece is intended to help billing staff, laboratory managers, and policy analysts understand the clinical purpose and billing classification of CPT code 80327, how it fits within laboratory toxicology services, and what to expect in payer interactions and claims adjudication.