CPT code 78430 represents a PET myocardial perfusion imaging study with CT transmission scan used to evaluate myocardial blood flow and cardiac function. The code covers a single study performed at rest or with pharmacologic or exercise stress, and it may incorporate ejection fraction and ventricular wall motion assessment when those measurements are obtained. Nationally, PET myocardial perfusion imaging is an important advanced cardiac imaging modality for assessing ischemia, perfusion abnormalities, and ventricular function in patients with suspected or known coronary artery disease.

Key payers covered in this analysis include Aetna, Blue Cross Blue Shield, Cigna Health, UnitedHealthcare, and Medicare. Readers will find a concise clinical context for CPT code 78430, benchmarks and utilization patterns where available, and an outline of common billing and coding considerations relevant to payers and providers. The publication summarizes service settings, typical clinical indications, and how CPT code 78430 fits within cardiac imaging service lines. Data on associated modifiers, taxonomies, and ICD‑10 diagnoses are not available in the input and are noted as such elsewhere in the full publication.