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    v1.0.30
    OpenPayerBilling CodesClinical Brachytherapy Radiation TreatmentCPT cpt-77768-surface-brachytherapy-skin-tumor-large-or-multiple-lesions
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    CPT 77768: Surface Brachytherapy for Skin Tumor >2.0 cm

    Medicare pays $257 on average nationally for this procedure.

    CPT code 77768 describes high-dose surface brachytherapy for treatment of a skin tumor greater than 2.0 cm in diameter, multiple skin lesions, or procedures using two or more channels, with inclusion of pre-loading dose calculation when performed; service type is high-energy radioactive surface brachytherapy and the typical site of service is an outpatient radiation oncology clinic or hospital outpatient department where surface applicators or catheters are placed on or near the skin for localized radiation delivery.

    For related coverage guidance, see recent payer policy updates: Percutaneous Electrical Nerve Field Stimulation for Functional Abdominal Pain Disorders, Esophagogastroduodenoscopy (EGD) Coverage Policy, Radiofrequency Therapy for Fecal Incontinence.

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    Table of contents

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    Clinical & Coding Specifications

    Clinical Context

    A 72-year-old male with a history of significant sun exposure presents to a dermatology radiation oncology clinic with a 2.5 cm squamous cell carcinoma of the scalp confirmed by biopsy. The lesion is superficial but wide and in a cosmetically sensitive area. After multidisciplinary discussion, the team elects high dose-rate (HDR) surface brachytherapy using multiple applicator channels to deliver a conformal dose to the skin surface while sparing underlying brain tissue. On the day of service the patient is seen in an outpatient radiation oncology suite: consent is confirmed, the treatment area is mapped and immobilized, treatment planning CT is performed, the radioactive source dwell positions and dwell times are calculated and verified, applicators/catheters are loaded with the high-energy radioactive source, treatment is delivered, and the applicators are removed. Documentation includes pre-procedure evaluation, dose calculation and verification, time of source loading, number of channels used, and post-treatment instructions. Typical sites of service are outpatient radiation oncology centers or hospital outpatient departments. The service type is radiation therapy — high dose-rate surface brachytherapy for a skin tumor over 2.0 cm in diameter or multiple lesions.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    77761Remote afterloading high dose rate radionuclide brachytherapy, interstitial; simple, single implant, per fractionMay be used for interstitial HDR brachytherapy procedures when lesions require tunneled or implanted catheters rather than surface applicators
    77762Remote afterloading high dose rate radionuclide brachytherapy, interstitial; complex, multiple implants, per fractionUsed when multiple interstitial implants are needed for extensive disease beyond surface applicators
    77295Special dosimetry for radiotherapy (e.g., radiosurgery), complex calculationsUsed for complex dose calculations and treatment planning beyond standard planning included in 77768 when required
    77336Continuing medical physics consultation, review and report for radiation oncology treatment planMay be reported for medical physics oversight or additional consultation related to HDR planning
    77427Radiation treatment management, 5 treatmentsRepresents fractionated external beam management when combined modality therapy occurs; billed per management visit series

    Related Modifiers

    10 rows

    ModifierDescriptionWhen to Use
    26Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
    50Modifier –50 (Bilateral Procedure) is appended to a CPT code when an identical procedure is performed on paired anatomical structures during the same operative session. The AMA states to add…- Use modifier -50 when the same CPT surgical, diagnostic, or radiology procedure is performed on paired anatomical structures (both sides of the body) during the same operative/session by the same…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    59Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    76Modifier -76, Repeat Procedure or Service by Same Physician or Other Qualified Health Care Professional, is appended when the same provider performs an identical, medically necessary procedure or…- Use modifier -76 when the same physician or other qualified health care professional performs an identical procedure or service a second (or subsequent) time on the same date of service and the…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…
    80CPT® Modifier 80 (Assistant Surgeon) is appended to a surgical CPT code when a physician (MD or DO) provides full, continuous assistance throughout the operative procedure. It is intended only for…- Use CPT Modifier -80 when a physician (MD or DO) serves as an assistant surgeon and provides full, continuous assistance throughout the entire operative procedure; append -80 to the surgical CPT…
    82Modifier 82 is appended to a surgical CPT code to indicate that an attending physician acted as an assistant because a qualified resident surgeon was unavailable. In teaching hospitals it documents…- When to use: Append modifier 82 in teaching-hospital settings to indicate a physician served as an assistant surgeon because a qualified resident surgeon was unavailable (includes situations where…

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    174400000X
    207RC0000X
    208000000X
    208600000X
    102L00000X
    363LC0200X
    207RI0200X
    246QM0706X

    Related ICD-10-CM Codes

    21 rows

    ICD-10-CM CodeDescription
    B07.8Other viral warts
    B07.9Viral wart, unspecified
    C43.0Malignant melanoma of lip
    C43.9Malignant melanoma of skin, unspecified
    C44.91Basal cell carcinoma of skin, unspecified
    C44.92Squamous cell carcinoma of skin, unspecified
    C44.99Other specified malignant neoplasm of skin, unspecified
    D04.0Carcinoma in situ of skin of lip
    D04.9Carcinoma in situ of skin, unspecified
    D48.5Neoplasm of uncertain behavior of skin

    Showing 1–10 of 21

    Related Payer Policy Updates

    Specialty: Gastroenterology1 / 3

    10 rows

    PolicyPayerEffective Date
    Percutaneous Electrical Nerve Field Stimulation for Functional Abdominal Pain Disordersbcbsvermont2026-12-01
    Esophagogastroduodenoscopy (EGD) Coverage Policyevicore2026-11-05
    Radiofrequency Therapy for Fecal IncontinenceCigna2026-10-15
    Magnetic Sphincter Augmentation for the Treatment of Gastroesophageal Reflux Disease (GERD)univerahealthcare2026-10-15
    High-Resolution Anoscopy (HRA)Premera Bluecross2026-10-01
    Gastroesophageal and Gastrointestinal (GI) Services and ProceduresColorado Rocky Mountain Health Plans2026-10-01
    Serum Testing for Hepatic Fibrosis in the Evaluation and Monitoring of Chronic Liver DiseaseOscar Health2026-10-01
    Fecal Analysis in the Diagnosis of Intestinal Dysbiosis and Fecal Microbiota Transplant TestingOscar Health2026-10-01
    Pancreatic Enzyme Testing for Acute PancreatitisOscar Health2026-10-01
    Helicobacter pylori TestingOscar Health2026-10-01

    Related Codes

    CPT-77750-INTRATUMORAL-RADIOELEMENT-INFUSION-HOSPITAL-ADMISSION-FOLLOW-UP

    CPT 77750: Radioelement Instillation to Destroy Tumor Cells

    CPT-77761-INTRACAVITARY-BRACHYTHERAPY-IMPLANT

    CPT 77761: Intracavitary Brachytherapy, 1–4 Sources

    CPT-77762-BRACHYTHERAPY-INTRACAVITARY-INTERSTITIAL-IMPLANT

    CPT 77762: Intracavitary Brachytherapy with 5–10 Sources

    CPT-77763-INTRACAVITARY-BRACHYTHERAPY-MULTI-SOURCE-IMPLANTATION

    CPT 77763: Intracavitary Brachytherapy, >10 Radioactive Sources

    CPT-77767-SURFACE-BRACHYTHERAPY-SKIN-TUMOR-SMALL-LESION

    CPT 77767: High-Dose-Rate Brachytherapy for Skin Tumor ≤2.0 cm

    CPT-77770-SINGLE-CHANNEL-BRACHYTHERAPY-CATHETER-PLACEMENT

    CPT 77770: Single-Channel Interstitial or Intracavitary Brachytherapy

    CPT-77771-BRACHYTHERAPY-INTERSTITIAL-INTRACAVITARY-MULTI-CHANNEL

    CPT 77771: Interstitial or Intracavitary Brachytherapy, 2–12 Channels

    CPT-77772-HIGH-DOSE-RATE-MULTI-CHANNEL-BRACHYTHERAPY

    CPT 77772: Interstitial or Intracavitary Brachytherapy, >12 Channels

    CPT-77778-INTERSTITIAL-BRACHYTHERAPY-MORE-THAN-10-SOURCES

    CPT 77778: Interstitial Brachytherapy, >10 Radioactive Sources

    CPT-77789-LOW-DOSE-RATE-SURFACE-BRACHYTHERAPY

    CPT 77789: Low–Dose–Rate Surface Brachytherapy

    Showing 1–10 of 12

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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