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    v1.0.30
    OpenPayerBilling CodesClinical Brachytherapy Radiation TreatmentCPT cpt-77763-intracavitary-brachytherapy-multi-source-implantation
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    CPT 77763: Intracavitary Brachytherapy, >10 Radioactive Sources

    Medicare pays $547 on average nationally for this procedure.

    CPT code 77763 describes intracavitary brachytherapy in which the provider places more than 10 radioactive sources or implants into a body cavity (for example the vagina, prostate, or bronchial tree) to deliver targeted radiation therapy for cancer; this is a procedural radiation oncology service typically performed in an operating room, procedure suite, or radiation oncology department and billed as a brachytherapy implant procedure for malignancy treatment.

    For related coverage guidance, see recent payer policy updates: Percutaneous Electrical Nerve Field Stimulation for Functional Abdominal Pain Disorders, Esophagogastroduodenoscopy (EGD) Coverage Policy, Radiofrequency Therapy for Fecal Incontinence.

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    Table of contents

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    Clinical & Coding Specifications

    Clinical Context

    A typical patient is a 68-year-old man with intermediate- to high-risk localized prostate adenocarcinoma who is evaluated by a multidisciplinary team including a radiation oncologist and urologist. After staging with prostate biopsy, prostate-specific antigen (PSA) trends, and pelvic MRI showing a lesion confined to the prostate with no distant metastasis, the team elects for brachytherapy using permanent or temporary radioactive source implants. The patient is seen in the outpatient radiation oncology clinic for pre-procedure education and consent, then scheduled for the procedure in an ambulatory surgery center or hospital operating room under monitored anesthesia care or general anesthesia.

    On the day of service the patient undergoes transperineal ultrasound-guided placement of more than 10 radioactive seeds or catheters into the prostate using a transrectal ultrasound template or stereotactic guidance. Intraoperative dosimetry verifies seed placement and target coverage. Post-implant imaging (CT or MRI) is obtained the same day or within 30 days to document implant geometry and dosimetry. Typical follow-up includes short-term assessment for urinary retention, hematuria, or rectal irritation, and serial PSA monitoring at regular intervals. The procedure is performed in settings such as hospital-based operating rooms, ambulatory surgery centers, or specialized radiation oncology suites equipped for brachytherapy.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    55873Brachytherapy, transperineal placement of permanent prostate implantsOften performed as an alternative technique for prostate brachytherapy; may be used in similar clinical workflows.
    77778Brachytherapy dose planning; complex, includes three-dimensional treatment planning requiring contouring and dose-volume histogramsCommonly performed pre- or post-implant to calculate dosimetry and document target coverage.
    77295Radiation therapy planning, complex, computerized three-dimensional treatment planUsed when comprehensive 3D planning is required for brachytherapy or combined modality care.
    77427Radiation treatment management, complicated; weekly management during radiation therapy courseUsed for management visits when patients receive fractionated external beam radiation in conjunction with brachytherapy.
    77014Computed tomography guidance for localization during interstitial procedures; simple or complex guidance as appropriateUsed for image guidance or post-implant CT to document seed location and dosimetry.

    Related Modifiers

    8 rows

    ModifierDescriptionWhen to Use
    26Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    73Modifier 73 indicates a facility-level outpatient hospital or ASC procedure that was discontinued after the patient was prepared and taken to the procedure/operating room but before any anesthesia…- When to use: Apply CPT modifier 73 on the FACILITY (outpatient hospital or ASC) claim when the patient has been fully prepared and physically taken into the procedure/operating room but the…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…
    80CPT® Modifier 80 (Assistant Surgeon) is appended to a surgical CPT code when a physician (MD or DO) provides full, continuous assistance throughout the operative procedure. It is intended only for…- Use CPT Modifier -80 when a physician (MD or DO) serves as an assistant surgeon and provides full, continuous assistance throughout the entire operative procedure; append -80 to the surgical CPT…
    82Modifier 82 is appended to a surgical CPT code to indicate that an attending physician acted as an assistant because a qualified resident surgeon was unavailable. In teaching hospitals it documents…- When to use: Append modifier 82 in teaching-hospital settings to indicate a physician served as an assistant surgeon because a qualified resident surgeon was unavailable (includes situations where…

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    207RH0000X
    208800000X
    2084P0800X
    208600000X
    133VN1401X
    207X00000X
    2471S1302X
    246ZX2200X

    Related ICD-10-CM Codes

    26 rows

    ICD-10-CM CodeDescription
    C16.9Malignant neoplasm of stomach, unspecified
    C18.9Malignant neoplasm of colon, unspecified
    C20Malignant neoplasm of rectum
    C22.0Liver cell carcinoma
    C25.9Malignant neoplasm of pancreas, unspecified
    C34.90Malignant neoplasm of unspecified part of unspecified bronchus or lung
    C43.9Malignant melanoma of skin, unspecified
    C44.01Basal cell carcinoma of skin of lip
    C44.90Unspecified malignant neoplasm of skin, unspecified
    C48.2Malignant neoplasm of peritoneum, unspecified

    Showing 1–10 of 26

    Related Payer Policy Updates

    Specialty: Gastroenterology1 / 3

    10 rows

    PolicyPayerEffective Date
    Percutaneous Electrical Nerve Field Stimulation for Functional Abdominal Pain Disordersbcbsvermont2026-12-01
    Esophagogastroduodenoscopy (EGD) Coverage Policyevicore2026-11-05
    Radiofrequency Therapy for Fecal IncontinenceCigna2026-10-15
    Magnetic Sphincter Augmentation for the Treatment of Gastroesophageal Reflux Disease (GERD)univerahealthcare2026-10-15
    High-Resolution Anoscopy (HRA)Premera Bluecross2026-10-01
    Gastroesophageal and Gastrointestinal (GI) Services and ProceduresColorado Rocky Mountain Health Plans2026-10-01
    Serum Testing for Hepatic Fibrosis in the Evaluation and Monitoring of Chronic Liver DiseaseOscar Health2026-10-01
    Fecal Analysis in the Diagnosis of Intestinal Dysbiosis and Fecal Microbiota Transplant TestingOscar Health2026-10-01
    Pancreatic Enzyme Testing for Acute PancreatitisOscar Health2026-10-01
    Helicobacter pylori TestingOscar Health2026-10-01

    Related Codes

    CPT-77750-INTRATUMORAL-RADIOELEMENT-INFUSION-HOSPITAL-ADMISSION-FOLLOW-UP

    CPT 77750: Radioelement Instillation to Destroy Tumor Cells

    CPT-77761-INTRACAVITARY-BRACHYTHERAPY-IMPLANT

    CPT 77761: Intracavitary Brachytherapy, 1–4 Sources

    CPT-77762-BRACHYTHERAPY-INTRACAVITARY-INTERSTITIAL-IMPLANT

    CPT 77762: Intracavitary Brachytherapy with 5–10 Sources

    CPT-77767-SURFACE-BRACHYTHERAPY-SKIN-TUMOR-SMALL-LESION

    CPT 77767: High-Dose-Rate Brachytherapy for Skin Tumor ≤2.0 cm

    CPT-77768-SURFACE-BRACHYTHERAPY-SKIN-TUMOR-LARGE-OR-MULTIPLE-LESIONS

    CPT 77768: Surface Brachytherapy for Skin Tumor >2.0 cm

    CPT-77770-SINGLE-CHANNEL-BRACHYTHERAPY-CATHETER-PLACEMENT

    CPT 77770: Single-Channel Interstitial or Intracavitary Brachytherapy

    CPT-77771-BRACHYTHERAPY-INTERSTITIAL-INTRACAVITARY-MULTI-CHANNEL

    CPT 77771: Interstitial or Intracavitary Brachytherapy, 2–12 Channels

    CPT-77772-HIGH-DOSE-RATE-MULTI-CHANNEL-BRACHYTHERAPY

    CPT 77772: Interstitial or Intracavitary Brachytherapy, >12 Channels

    CPT-77778-INTERSTITIAL-BRACHYTHERAPY-MORE-THAN-10-SOURCES

    CPT 77778: Interstitial Brachytherapy, >10 Radioactive Sources

    CPT-77789-LOW-DOSE-RATE-SURFACE-BRACHYTHERAPY

    CPT 77789: Low–Dose–Rate Surface Brachytherapy

    Showing 1–10 of 12

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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