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    OpenPayerBilling CodesDiagnostic Radiology (Diagnostic Imaging) Procedures of the HeartCPT cpt-75577-coronary-cta-plaque-quantification-post-processing
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    CPT 75577: Coronary CTA Plaque Quantification and Report

    Medicare pays $707 on average nationally for this procedure.

    CPT code 75577 describes a physician or qualified healthcare professional's review and report of computer-assisted analysis of a previously performed coronary computed tomographic angiography (CTA) to quantify and characterize coronary atherosclerotic plaque; this is a diagnostic imaging post-processing service performed on existing CTA data and typically provided in an ambulatory radiology or cardiology imaging setting where software-based plaque quantification tools are available.

    For related coverage guidance, see recent payer policy updates: Automated Ambulatory Blood Pressure Monitoring for Diagnosis of Hypertension in Patients with Elevated Office Blood Pressure, Cardiology - Ivabradine, Cardiac Computed Tomography (CCT)/Coronary Computed Tomographic Angiography (CCTA).

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    Clinical & Coding Specifications

    Clinical Context

    A 62-year-old patient with hyperlipidemia and increasing exertional chest discomfort underwent coronary computed tomographic angiography (CTA) at an outpatient imaging center. The CTA acquisition was completed and stored in the picture archiving and communication system. The cardiologist orders quantitative plaque analysis using dedicated software to characterize and measure coronary atherosclerotic plaque burden and composition (calcified, non-calcified, mixed) to inform risk stratification and guide medical management. A radiologist or cardiologist with expertise in cardiac CT reviews the computer-generated plaque quantification, verifies automated segmentations, adjusts measurements if needed, interprets findings in the clinical context, and issues a formal report to the referring provider. Typical site of service is an outpatient radiology or cardiology imaging facility with cardiac CT capability; may also occur in a hospital radiology department when studies are performed during inpatient or observation stays.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    75574Computed tomographic angiography, heart, without contrast material(s), with contrast material(s), including image post-processing when performed; for coronary arteries (single study)Represents the acquisition CTA study that provides the imaging dataset used as the input for plaque quantification; typically performed before 75577.
    71275Computed tomography, thorax, with contrast material, including non-contrast and contrast enhanced phases, with further image processing (high resolution)May be performed in some protocols that include chest CTA components; not specific to coronary plaque but related thoracic CT work.
    0144TCoronary artery calcium scoring using CT, without contrast; interpretation and report (Category III)Calcium scoring is a related quantification measuring calcified plaque burden and often reported alongside or prior to detailed plaque characterization.
    93799Unlisted cardiology service or procedureUsed when a specific related cardiac imaging or analysis component does not have a reportable CPT code; occasionally used in complex workflows requiring unlisted coding.
    76937Ultrasound guidance for vascular access; real-time needle guidance, imaging supervision and interpretationMay be part of interventional workflows in which plaque quantification informs planning for downstream invasive procedures requiring vascular access.

    Related Modifiers

    5 rows

    ModifierDescriptionWhen to Use
    26Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
    59Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
    51Modifier –51 (Multiple Procedures) is used when the same provider performs multiple procedures in the same session to identify secondary, non‑exempt procedures and indicate payment reduction logic…- Use modifier -51 when the same provider performs multiple distinct procedures during the same patient encounter: report the highest‑valued procedure first (no modifier) and append -51 to…
    76Modifier -76, Repeat Procedure or Service by Same Physician or Other Qualified Health Care Professional, is appended when the same provider performs an identical, medically necessary procedure or…- Use modifier -76 when the same physician or other qualified health care professional performs an identical procedure or service a second (or subsequent) time on the same date of service and the…
    77Modifier 77 indicates that a previously performed procedure or service was legitimately repeated by a different physician or other qualified health care professional. The AMA’s CPT definition…- Use modifier 77 when a basic procedure or service already performed is repeated by a different physician or other qualified health care professional (for example, a second provider independently…

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    207RC0000X
    207RG0300X
    207RP1001X
    207QB0002X
    363LN0005X
    224ZF0002X
    261QA0005X
    103GC0700X

    Related Payer Policy Updates

    Specialty: Cardiology1 / 3

    10 rows

    PolicyPayerEffective Date
    Automated Ambulatory Blood Pressure Monitoring for Diagnosis of Hypertension in Patients with Elevated Office Blood PressureBluecross Idaho2026-11-01
    Cardiology - IvabradineCigna2026-10-15
    Cardiac Computed Tomography (CCT)/Coronary Computed Tomographic Angiography (CCTA)univerahealthcare2026-10-15
    Percutaneous Ventricular Assist DeviceUnitedHealthcare2026-10-01
    Cardiovascular Disease Risk AssessmentOscar Health2026-10-01
    Biomarkers for Myocardial Infarction and Chronic Heart FailureOscar Health2026-10-01
    Multiple Procedure Payment Reduction for Diagnostic Cardiovascular ProceduresBlue Cross Blue Shield - Maine2026-10-01
    Left Atrial Appendage Closure Devicesexcellus_health_plan_inc2026-09-17
    Left Atrial Appendage Closure Devicesuniverahealthcare2026-09-17
    Cardiac Omnibus CodesCigna2026-09-15

    Related Codes

    CPT-75557-CARDIAC-MRI-NON-CONTRAST-STRUCTURE-AND-FUNCTION

    CPT 75557: Cardiac MRI Morphology and Function, No Contrast

    CPT-75559-CARDIAC-MRI-STRESS-NON-CONTRAST

    CPT 75559: Cardiac MRI with Stress, Non-Contrast

    CPT-75561-CARDIAC-MRI-WITH-AND-WITHOUT-CONTRAST

    CPT 75561: Cardiac MRI, Non-Contrast Followed by Contrast

    CPT-75563-CARDIAC-MRI-STRESS-REST-WITH-AND-WITHOUT-CONTRAST

    CPT 75563: Cardiac MRI Stress Study, With and Without Contrast

    CPT-75565-CARDIAC-MRI-VELOCITY-FLOW-MAPPING

    CPT 75565: Cardiac MRI with Velocity (Flow) Mapping

    CPT-75571-CORONARY-CALCIUM-SCORING-CT-NON-CONTRAST

    CPT 75571: Coronary Artery Calcium Scoring by Non-Contrast CT

    CPT-75572-CARDIAC-CT-3D-POST-PROCESSING-FUNCTIONAL-ASSESSMENT

    CPT 75572: Cardiac CT with 3D Post-Processing and Function Assessment

    CPT-75573-CARDIAC-CT-CONGENITAL-HEART-EVALUATION

    CPT 75573: Cardiac CT for Congenital Heart Anomaly Evaluation

    CPT-75574-CARDIAC-CT-WITH-CONTRAST-CORONARY-EVALUATION

    CPT 75574: Contrast-Enhanced Cardiac CT Angiography

    CPT-75580-FFR-CT-FROM-CCTA-AUGMENTATION-SOFTWARE-REPORT

    CPT 75580: CTA-Derived Coronary Fractional Flow Reserve Estimation

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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