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    v1.0.30
    OpenPayerBilling CodesLaparoscopic Procedures on the KidneyCPT cpt-50546-laparoscopic-nephrectomy-with-partial-ureterectomy
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    CPT 50546: Laparoscopic Nephroureterectomy with Partial Ureter Removal

    Medicare pays $1097 on average nationally for this procedure.

    CPT code 50546 describes a surgical laparoscopic nephroureterectomy in which the provider removes a kidney and part of the ureter; the service is a laparoscopic urologic extirpative procedure typically performed in an operating room or hospital inpatient setting and may be performed via minimally invasive techniques for treatment of renal and upper urinary tract pathology.

    For related coverage guidance, see recent payer policy updates: Surgical Procedures, Outpatient Surgical Procedures - Site of Service, Site of Service Ambulatory Service Center (ASC) Select — Surgical or Diagnostic Procedures in Adults.

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    Table of contents

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    Clinical & Coding Specifications

    Clinical Context

    A typical patient is a 58-year-old adult presenting with flank pain, hematuria, and imaging-confirmed nonfunctioning or diseased kidney due to chronic infection, obstructive uropathy, renal mass, or severe calculous disease. After evaluation by a urologist including history, physical exam, urinalysis, renal function testing, and cross-sectional imaging (CT or MRI), the patient is scheduled for a laparoscopic nephrectomy with partial ureterectomy under general anesthesia. The preoperative workflow includes informed consent, optimization of comorbid conditions, anesthesia evaluation, and review of imaging to plan port placement and approach. Intraoperative steps include laparoscopic access, mobilization of the kidney, ligation of the renal hilum, division of the ureter distally as indicated, specimen extraction (often via an extension of a port site or a small incision), hemostasis, and placement of drains if required. Postoperative care includes pain control, monitoring of renal function, assessment for complications (bleeding, infection, urine leak), and discharge planning with follow-up for pathology if a neoplasm was resected.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    50545Laparoscopy, surgical; nephrectomy, complete or partial, including partial ureterectomyOften closely related; 50545 can describe similar laparoscopic nephrectomy procedures and may be used when coding variations exist between complete and partial procedures.
    49900Exploratory laparotomy, exploratory celiotomy with or without aspiration; not otherwise specifiedMay be used if conversion from laparoscopic to open approach is required during the case.
    52648Cystoureteroscopy, with ureteroscopy and/or pyeloscopy; with removal of ureteral calculus or ureteral stone, with ureteral stent placementMay be performed preoperatively or postoperatively for concomitant ureteral stone management as part of staged care.
    50300Nephrectomy, partial, any method; with or without partial ureterectomyOpen or other approach for partial nephrectomy when laparoscopic approach is not used or conversion occurs.
    36415Collection of venous blood by venipunctureCommon preoperative service for labs including CBC, chemistries, and crossmatch if needed.

    Related Modifiers

    11 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    54Modifier ‑54 (“Surgical care only”) is appended to a CPT surgical procedure when the reporting surgeon performs the intraoperative (surgical) component but does not furnish the preoperative and/or…- Use modifier -54 when the reporting surgeon provided only the intraoperative (surgical) component of a procedure and preoperative and/or postoperative management has been or will be provided by…
    55Modifier –55 indicates the billing provider furnished only postoperative management for a procedure that has a global surgical period. According to AAPC, this modifier is appended to the same CPT…- Use modifier -55 when billing the same CPT surgical code that has a 10- or 90-day global period and you, as a provider other than the original surgeon, furnished ONLY postoperative management (no…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    63Modifier‑63 is appended to surgical CPT codes (20000–69990) when a procedure is performed on a neonate or infant weighing ≤ 4 kg (about 8.8 lbs). The AMA/AAPC definition specifies this use and notes…- Use modifier -63 only for surgical procedures in the CPT 20000–69990 series performed on a neonate or infant who weighs ≤ 4 kg at the time of the procedure; it indicates increased complexity due to…
    66Modifier 66 (Surgical Team) is used when three or more surgeons act as primary surgeons on a single, highly complex procedure. The AMA defines it for use when a surgical team — often composed of…- Use modifier 66 when three or more surgeons act as primary surgeons working collaboratively as a surgical team on a single, highly complex or difficult procedure (for example organ…
    80CPT® Modifier 80 (Assistant Surgeon) is appended to a surgical CPT code when a physician (MD or DO) provides full, continuous assistance throughout the operative procedure. It is intended only for…- Use CPT Modifier -80 when a physician (MD or DO) serves as an assistant surgeon and provides full, continuous assistance throughout the entire operative procedure; append -80 to the surgical CPT…
    81Modifier -81 indicates a physician served as a minimal assistant surgeon for part—not all—of an operative procedure. Use when a physician’s assisting role is limited and does not represent full…- Use CPT modifier -81 when a physician acts as a minimum assistant surgeon who assists during only part (a limited portion) of an operative procedure; append -81 to the primary surgical CPT code to…

    Showing 1–10 of 11

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    208800000X
    207L00000X
    208D00000X
    261QS1000X
    261QP2300X
    261QP2400X
    175L00000X
    372500000X

    Related Payer Policy Updates

    Specialty: General Surgery1 / 2

    10 rows

    PolicyPayerEffective Date
    Surgical ProceduresUnitedHealthcare2026-09-01
    Outpatient Surgical Procedures - Site of ServiceUnitedHealthcare2026-09-01
    Site of Service Ambulatory Service Center (ASC) Select — Surgical or Diagnostic Procedures in AdultsPremera Bluecross2026-09-01
    Site of Service Ambulatory Surgical Center (ASC) Select — Surgical or Diagnostic Procedures in AdultsPremera Bluecross2026-09-01
    Site of Service Ambulatory Service Center (ASC) SelectPremera Bluecross2026-09-01
    Site of Service Ambulatory Surgical Center (ASC) Select — Site of Service for Ambulatory Surgical Procedures (ASC Select)Premera Bluecross2026-09-01
    Site of Service Ambulatory Service Center (ASC) SelectPremera Bluecross2026-09-01
    Outpatient Surgical Procedures - Site of Servicesierra health and life2026-08-01
    Medical Necessity Guidelines — Inpatient Surgical CareMass General Brigham Health Plan2026-08-01
    Ambulatory Surgery Center (ASC) - Site of Care PolicyKaiser Permanente2026-08-01

    Related Codes

    CPT-50541-LAPAROSCOPIC-RENAL-CYST-ABLATION-CRYO-RFA

    CPT 50541: Laparoscopic Destruction of Renal Cysts

    CPT-50542-LAPAROSCOPIC-RENAL-MASS-ABLATION-CRYO-RADIOFREQUENCY

    CPT 50542: Laparoscopic Destruction of Renal Mass Lesion(s)

    CPT-50543-LAPAROSCOPIC-PARTIAL-NEPHRECTOMY

    CPT 50543: Laparoscopic Partial Nephrectomy

    CPT-50544-PYELOPLASTY-URETEROPELVIC-JUNCTION-REPAIR

    CPT 50544: Pyeloplasty to Repair Ureteropelvic Junction Obstruction

    CPT-50545-RADICAL-NEPHRECTOMY-KIDNEY-AND-SURROUNDING-STRUCTURES

    CPT 50545: Radical Nephrectomy Including Gerota's Fascia

    CPT-50547-LAPAROSCOPIC-DONOR-NEPHRECTOMY-COLD-PRESERVATION

    CPT 50547: Laparoscopic Living Donor Nephrectomy

    CPT-50548-LAPAROSCOPIC-NEPHROURETERECTOMY-KIDNEY-AND-URETER-REMOVAL

    CPT 50548: Laparoscopic Nephroureterectomy

    CPT-50549-LAPAROSCOPIC-RENAL-UNLISTED-PROCEDURE

    CPT 50549: Laparoscopic Renal Procedure, Unlisted

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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