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    OpenPayerBilling CodesExcision and Destruction Procedures on the Abdomen, Peritoneum, and OmentumCPT cpt-49255-omentectomy-for-metastatic-abdominal-pelvic-cancer
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    CPT 49255: Omentectomy, Excision of Omentum for Metastatic Disease

    Medicare pays $761 on average nationally for this procedure.

    CPT code 49255 describes surgical excision of the omentum (omentectomy), typically performed for treatment of metastatic abdominal or pelvic cancer; this is an operative abdominal procedure used to remove the omental tissue and is usually performed in an inpatient or outpatient hospital operating room or specialized surgical center depending on patient condition and extent of disease.

    For related coverage guidance, see recent payer policy updates: Surgical Procedures, Outpatient Surgical Procedures - Site of Service, Site of Service Ambulatory Service Center (ASC) Select — Surgical or Diagnostic Procedures in Adults.

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    Table of contents

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    Clinical & Coding Specifications

    Clinical Context

    A typical patient is a 62-year-old woman with known ovarian carcinoma who presents with evidence of peritoneal carcinomatosis and symptomatic ascites. After staging imaging and multidisciplinary tumor board review, the surgical oncology team schedules a cytoreductive laparotomy. Intraoperatively, visible tumor implants are found on the omentum and the surgeon performs an omentectomy to remove the omentum for tumor debulking and to obtain tissue for pathology. The workflow includes preoperative oncologic evaluation, informed consent noting risks of bleeding and infection, general anesthesia in an operating room or ambulatory surgical center if appropriate, performance of CPT 49255 (excision of omentum), specimen submission to surgical pathology, postoperative recovery with monitoring for ileus or wound complications, and coordination with medical oncology for adjuvant therapy based on final pathology.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    32551Thoracotomy, with decortication, pleurectomy, or other intrathoracic procedure (example)Not typically related; Data not available in the input.
    49000Unlisted laparotomy procedure, exploratoryMay be used for additional exploratory abdominal work not described by standard codes performed at the same operation as CPT 49255.
    58662Laparoscopy, surgical; with lysis of adhesions (salpingolysis, ovariolysis)May be performed laparoscopically as part of staging or cytoreduction in select cases where omentectomy is done minimally invasively.
    88305Surgical pathology, gross and microscopic examinationPathology coding used to report examination of the excised omentum specimen submitted after CPT 49255.
    44960Enterostomy, colostomy or ileostomy procedure (example)May be performed concurrently if bowel resection or diversion is required during cytoreductive surgery.

    Related Modifiers

    11 rows

    ModifierDescriptionWhen to Use
    51Modifier –51 (Multiple Procedures) is used when the same provider performs multiple procedures in the same session to identify secondary, non‑exempt procedures and indicate payment reduction logic…- Use modifier -51 when the same provider performs multiple distinct procedures during the same patient encounter: report the highest‑valued procedure first (no modifier) and append -51 to…
    59Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…
    79Modifier 79 indicates a surgical procedure performed during the postoperative global period of a prior surgery that is unrelated to the original procedure. Per AMA/CPT and CMS guidance, it is…- Use modifier 79 when the same physician (or same‑specialty physician in the same group) performs a surgical procedure during the postoperative global period of a prior surgery and the new procedure…
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    76Modifier -76, Repeat Procedure or Service by Same Physician or Other Qualified Health Care Professional, is appended when the same provider performs an identical, medically necessary procedure or…- Use modifier -76 when the same physician or other qualified health care professional performs an identical procedure or service a second (or subsequent) time on the same date of service and the…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    80CPT® Modifier 80 (Assistant Surgeon) is appended to a surgical CPT code when a physician (MD or DO) provides full, continuous assistance throughout the operative procedure. It is intended only for…- Use CPT Modifier -80 when a physician (MD or DO) serves as an assistant surgeon and provides full, continuous assistance throughout the entire operative procedure; append -80 to the surgical CPT…

    Showing 1–10 of 11

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    207V00000X
    2080P0208X
    207L00000X
    208600000X
    207K00000X
    207X00000X
    207VX0000X
    103TF0000X

    Related ICD-10-CM Codes

    24 rows

    ICD-10-CM CodeDescription
    C16.9Malignant neoplasm of stomach, unspecified
    C18.9Malignant neoplasm of colon, unspecified
    C20Malignant neoplasm of rectum
    C22.8Malignant neoplasm of liver, primary, unspecified as to type
    C25.9Malignant neoplasm of pancreas, unspecified
    C34.90Malignant neoplasm of unspecified part of unspecified bronchus or lung
    C43.9Malignant melanoma of skin, unspecified
    C50.912Malignant neoplasm of unspecified site of left female breast
    C53.9Malignant neoplasm of cervix uteri, unspecified
    C54.9Malignant neoplasm of corpus uteri, unspecified

    Showing 1–10 of 24

    Related Payer Policy Updates

    Specialty: General Surgery1 / 2

    10 rows

    PolicyPayerEffective Date
    Surgical ProceduresUnitedHealthcare2026-09-01
    Outpatient Surgical Procedures - Site of ServiceUnitedHealthcare2026-09-01
    Site of Service Ambulatory Service Center (ASC) Select — Surgical or Diagnostic Procedures in AdultsPremera Bluecross2026-09-01
    Site of Service Ambulatory Surgical Center (ASC) Select — Surgical or Diagnostic Procedures in AdultsPremera Bluecross2026-09-01
    Site of Service Ambulatory Service Center (ASC) SelectPremera Bluecross2026-09-01
    Site of Service Ambulatory Surgical Center (ASC) Select — Site of Service for Ambulatory Surgical Procedures (ASC Select)Premera Bluecross2026-09-01
    Site of Service Ambulatory Service Center (ASC) SelectPremera Bluecross2026-09-01
    Outpatient Surgical Procedures - Site of Servicesierra health and life2026-08-01
    Medical Necessity Guidelines — Inpatient Surgical CareMass General Brigham Health Plan2026-08-01
    Ambulatory Surgery Center (ASC) - Site of Care PolicyKaiser Permanente2026-08-01

    Related Codes

    CPT-49180-PERCUTANEOUS-ABDOMINAL-NEEDLE-BIOPSY

    CPT 49180: Percutaneous Abdominal/Retroperitoneal Needle Biopsy

    CPT-49185-PERCUTANEOUS-CHEMICAL-DESTRUCTION-FLUID-COLLECTION

    CPT 49185: Percutaneous Chemical Destruction of Fluid Collection

    CPT-49186-OPEN-ABDOMINAL-EXCISION-DESTRUCTION-SMALL-TUMORS-CYSTS

    CPT 49186: Open Excision/Destruction of Abdominal Tumors or Cysts ≤5 cm

    CPT-49187-OPEN-ABDOMINAL-TUMOR-CYST-EXCISION-5-1-10CM

    CPT 49187: Open Excision or Destruction of Abdominal Tumors/Cysts, 5.1–10 cm

    CPT-49188-OPEN-EXCISION-ABDOMINAL-TUMORS-10-1-20-CM

    CPT 49188: Open Abdominal Excision/Destruction of Tumor(s)/Cyst(s)

    CPT-49189-OPEN-ABDOMINAL-TUMOR-CYST-EXCISION-20-1-30CM

    CPT 49189: Open Excision/Destruction of Abdominal Tumors or Cysts (20.1–30 cm)

    CPT-49190-OPEN-ABDOMINAL-TUMOR-CYST-EXCISION-DESTRUCTION-OVER-30CM

    CPT 49190: Open Excision/Destruction of Abdominal Tumors or Cysts >30 cm

    CPT-49215-SACROCOCCYGEAL-MASS-EXCISION

    CPT 49215: Excision of Sacrococcygeal Tumor

    CPT-49250-UMBILICAL-EXCISION-HERNIA-INFECTION

    CPT 49250: Excision of Umbilicus (Umbilectomy)

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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