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    OpenPayerBilling CodesExcision and Destruction Procedures on the Abdomen, Peritoneum, and OmentumCPT cpt-49188-open-excision-abdominal-tumors-10-1-20-cm
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    CPT 49188: Open Abdominal Excision/Destruction of Tumor(s)/Cyst(s)

    Medicare pays $1869 on average nationally for this procedure.

    CPT code 49188 describes an open abdominal procedure to excise or destroy one or more tumors or cysts with a combined maximum length of 10.1 to 20 cm, classified as an open surgical excision of intra-abdominal masses; the service type is open surgical excision/destruction and the typical site of service is the operating room in an inpatient or outpatient surgical facility.

    For related coverage guidance, see recent payer policy updates: Surgical Procedures, Outpatient Surgical Procedures - Site of Service, Site of Service Ambulatory Service Center (ASC) Select — Surgical or Diagnostic Procedures in Adults.

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    Table of contents

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    Clinical & Coding Specifications

    Clinical Context

    A 52-year-old female presents with progressive abdominal distension and intermittent dull right lower quadrant pain. Cross-sectional imaging (CT abdomen/pelvis) identifies multiple intra-abdominal cystic and solid lesions with a combined maximum linear length measured at 14 cm. The surgical team schedules an open abdominal procedure to excise the tumors/cysts due to size, location, and concern for malignancy. Preoperative workup includes history and physical, labs (CBC, CMP, coagulation studies), informed consent, anesthesia evaluation, and intraoperative pathology (frozen section) as indicated. Intraoperatively, an open midline laparotomy is performed, lesions are identified and resected en bloc with appropriate margin when possible, hemostasis achieved, and abdominal wall closed. Postoperative care includes pain control, wound monitoring, early ambulation, serial abdominal exams, and pathology review to guide further oncologic management. Typical sites of service include an inpatient hospital operating room or ambulatory surgical center for complex open abdominal tumor excisions. The service type is operative open abdominal tumor/cyst excision corresponding to 49188.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    19303Mastectomy, simple, completeNot directly related to abdominal excision; included only when metastatic disease requires mastectomy in the same care episode — otherwise not typically performed with 49188.

    49000 | Exploratory laparotomy, exploratory celiotomy with or without biopsy(s) (separate procedure) | Performed when initial exploration and biopsy are needed prior to definitive excision; may precede 49188 in diagnostic workflows.

    49010 | Laparotomy, exploratory, with biopsy(s) of intra-abdominal organ(s) | Used for targeted biopsies if frozen section or diagnostic confirmation is required before or instead of full excision.

    49900 | Unlisted laparoscopy procedure, abdomen, peritoneum and omentum | May be reported when a concurrent or prior laparoscopic procedure is performed and no specific CPT exists; complementary in mixed open/laparoscopic cases.

    99152 is not in the provided list and therefore not included. | Data not applicable | Data not applicable

    Note: Related CPT codes provided in the input were empty; the table above lists commonly associated codes used in clinical workflows with open abdominal tumor/cyst excision.

    Related Modifiers

    12 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    23Modifier -23 (Unusual Anesthesia) is used on anesthesia service CPT codes when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia…- Use modifier -23 only on anesthesia CPT codes (00100–01999) when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia because of…
    50Modifier –50 (Bilateral Procedure) is appended to a CPT code when an identical procedure is performed on paired anatomical structures during the same operative session. The AMA states to add…- Use modifier -50 when the same CPT surgical, diagnostic, or radiology procedure is performed on paired anatomical structures (both sides of the body) during the same operative/session by the same…
    51Modifier –51 (Multiple Procedures) is used when the same provider performs multiple procedures in the same session to identify secondary, non‑exempt procedures and indicate payment reduction logic…- Use modifier -51 when the same provider performs multiple distinct procedures during the same patient encounter: report the highest‑valued procedure first (no modifier) and append -51 to…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    59Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…
    80CPT® Modifier 80 (Assistant Surgeon) is appended to a surgical CPT code when a physician (MD or DO) provides full, continuous assistance throughout the operative procedure. It is intended only for…- Use CPT Modifier -80 when a physician (MD or DO) serves as an assistant surgeon and provides full, continuous assistance throughout the entire operative procedure; append -80 to the surgical CPT…

    Showing 1–10 of 12

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    207L00000X
    208000000X
    2086S0122X
    207K00000X
    3245S0500X
    246RH0600X
    207KI0005X
    207RE0101X

    Related ICD-10-CM Codes

    26 rows

    ICD-10-CM CodeDescription
    C16.9Malignant neoplasm of stomach, unspecified
    C18.9Malignant neoplasm of colon, unspecified
    C22.9Malignant neoplasm of liver, not specified as primary or secondary
    C56.9Malignant neoplasm of unspecified ovary
    C78.2Secondary malignant neoplasm of pleura
    C78.7Secondary malignant neoplasm of liver and intrahepatic bile duct
    D12.6Benign neoplasm of colon, unspecified
    D13.4Benign neoplasm of liver
    D17.9Benign lipomatous neoplasm, unspecified
    D48.4Neoplasm of uncertain behavior of peritoneum

    Showing 1–10 of 26

    Related Payer Policy Updates

    Specialty: General Surgery1 / 2

    10 rows

    PolicyPayerEffective Date
    Surgical ProceduresUnitedHealthcare2026-09-01
    Outpatient Surgical Procedures - Site of ServiceUnitedHealthcare2026-09-01
    Site of Service Ambulatory Service Center (ASC) Select — Surgical or Diagnostic Procedures in AdultsPremera Bluecross2026-09-01
    Site of Service Ambulatory Surgical Center (ASC) Select — Surgical or Diagnostic Procedures in AdultsPremera Bluecross2026-09-01
    Site of Service Ambulatory Service Center (ASC) SelectPremera Bluecross2026-09-01
    Site of Service Ambulatory Surgical Center (ASC) Select — Site of Service for Ambulatory Surgical Procedures (ASC Select)Premera Bluecross2026-09-01
    Site of Service Ambulatory Service Center (ASC) SelectPremera Bluecross2026-09-01
    Outpatient Surgical Procedures - Site of Servicesierra health and life2026-08-01
    Medical Necessity Guidelines — Inpatient Surgical CareMass General Brigham Health Plan2026-08-01
    Ambulatory Surgery Center (ASC) - Site of Care PolicyKaiser Permanente2026-08-01

    Related Codes

    CPT-49180-PERCUTANEOUS-ABDOMINAL-NEEDLE-BIOPSY

    CPT 49180: Percutaneous Abdominal/Retroperitoneal Needle Biopsy

    CPT-49185-PERCUTANEOUS-CHEMICAL-DESTRUCTION-FLUID-COLLECTION

    CPT 49185: Percutaneous Chemical Destruction of Fluid Collection

    CPT-49186-OPEN-ABDOMINAL-EXCISION-DESTRUCTION-SMALL-TUMORS-CYSTS

    CPT 49186: Open Excision/Destruction of Abdominal Tumors or Cysts ≤5 cm

    CPT-49187-OPEN-ABDOMINAL-TUMOR-CYST-EXCISION-5-1-10CM

    CPT 49187: Open Excision or Destruction of Abdominal Tumors/Cysts, 5.1–10 cm

    CPT-49189-OPEN-ABDOMINAL-TUMOR-CYST-EXCISION-20-1-30CM

    CPT 49189: Open Excision/Destruction of Abdominal Tumors or Cysts (20.1–30 cm)

    CPT-49190-OPEN-ABDOMINAL-TUMOR-CYST-EXCISION-DESTRUCTION-OVER-30CM

    CPT 49190: Open Excision/Destruction of Abdominal Tumors or Cysts >30 cm

    CPT-49215-SACROCOCCYGEAL-MASS-EXCISION

    CPT 49215: Excision of Sacrococcygeal Tumor

    CPT-49250-UMBILICAL-EXCISION-HERNIA-INFECTION

    CPT 49250: Excision of Umbilicus (Umbilectomy)

    CPT-49255-OMENTECTOMY-FOR-METASTATIC-ABDOMINAL-PELVIC-CANCER

    CPT 49255: Omentectomy, Excision of Omentum for Metastatic Disease

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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