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    OpenPayerBilling CodesExcision and Destruction Procedures on the Abdomen, Peritoneum, and OmentumCPT cpt-49185-percutaneous-chemical-destruction-fluid-collection
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    CPT 49185: Percutaneous Chemical Destruction of Fluid Collection

    Medicare pays $1262 on average nationally for this procedure.

    CPT code 49185 describes a percutaneous, image-guided chemical destruction of a fluid collection (such as a lymphocele, cyst, or seroma) performed through a small skin incision with ultrasound or fluoroscopic guidance; the service includes the diagnostic study and radiological supervision and interpretation. Service type: percutaneous image-guided drainage/ablation procedure. Typical site of service: outpatient interventional radiology suite, ambulatory surgery center, or hospital radiology department using fluoroscopy or ultrasound imaging for real-time guidance.

    For related coverage guidance, see recent payer policy updates: Surgical Procedures, Outpatient Surgical Procedures - Site of Service, Site of Service Ambulatory Service Center (ASC) Select — Surgical or Diagnostic Procedures in Adults.

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    Table of contents

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    Clinical & Coding Specifications

    Clinical Context

    A 62-year-old male presents 3 weeks after open inguinal hernia repair with a progressively enlarging, fluctuant groin swelling, local tenderness, and low-grade fever. Ultrasound demonstrates a 5-cm fluid collection consistent with a seroma. The interventional radiologist is consulted and schedules a percutaneous, image-guided chemical ablation of the fluid collection using ultrasound guidance. In the procedure suite or outpatient interventional radiology (IR) unit, the patient is positioned and the skin prepped; local anesthetic is administered. Under real-time ultrasound (or fluoroscopic) guidance, a small skin puncture is made and a needle or catheter is advanced into the collection. Contrast may be injected to confirm location. A sclerosing agent is instilled to chemically obliterate the cavity; aspiration of fluid may be performed before or after instillation. The procedure includes diagnostic imaging, radiological supervision, and interpretation. Typical site of service is an outpatient interventional radiology suite, ambulatory surgery center, or hospital outpatient department. Typical clinical workflow includes preprocedure consent and coagulation review, image localization, needle/catheter placement, chemical instillation with monitoring, postprocedure ultrasound to confirm reduction, and brief recovery with discharge instructions and follow-up imaging or clinic visit.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    49083Percutaneous drainage, abdomen and/or retroperitoneal abscess, percutaneous catheter placement with imaging guidance (e.g., abscess, seroma)May be performed prior to or instead of chemical ablation for drainage and catheter placement; used when ongoing drainage is required.
    76942Ultrasonic guidance for needle placement (e.g., biopsy, aspiration, injection, localization device), imaging supervision and interpretationCommonly billed in conjunction with percutaneous chemical destruction when ultrasound guidance is used for needle/catheter placement.
    77012Fluoroscopic guidance for therapeutic injection procedures (remote)Used when fluoroscopic guidance is employed during needle/catheter placement or contrast injection to confirm positioning.
    49405Insertion of tunneled intraperitoneal catheter (e.g., peritoneal drainage)Occasionally related when larger or tunneled drainage access is required for recurrent fluid collections before chemical ablation.
    96440Chemotherapy administration subcutaneous or intramuscular; injection or infusion of sclerosant agents when reported under specific payer rules (note: payer policy varies)May be relevant when documentation and payer policy require coding for instillation of a sclerosant agent; clinical documentation must support appropriate use and billing.

    Related Modifiers

    11 rows

    ModifierDescriptionWhen to Use
    26Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
    59Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    76Modifier -76, Repeat Procedure or Service by Same Physician or Other Qualified Health Care Professional, is appended when the same provider performs an identical, medically necessary procedure or…- Use modifier -76 when the same physician or other qualified health care professional performs an identical procedure or service a second (or subsequent) time on the same date of service and the…
    77Modifier 77 indicates that a previously performed procedure or service was legitimately repeated by a different physician or other qualified health care professional. The AMA’s CPT definition…- Use modifier 77 when a basic procedure or service already performed is repeated by a different physician or other qualified health care professional (for example, a second provider independently…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…
    79Modifier 79 indicates a surgical procedure performed during the postoperative global period of a prior surgery that is unrelated to the original procedure. Per AMA/CPT and CMS guidance, it is…- Use modifier 79 when the same physician (or same‑specialty physician in the same group) performs a surgical procedure during the postoperative global period of a prior surgery and the new procedure…
    50Modifier –50 (Bilateral Procedure) is appended to a CPT code when an identical procedure is performed on paired anatomical structures during the same operative session. The AMA states to add…- Use modifier -50 when the same CPT surgical, diagnostic, or radiology procedure is performed on paired anatomical structures (both sides of the body) during the same operative/session by the same…

    Showing 1–10 of 11

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    207P00000X
    207K00000X
    208C00000X
    363A00000X
    208000000X
    171M00000X
    2471V0105X
    1835G0303X

    Related Payer Policy Updates

    Specialty: General Surgery1 / 2

    10 rows

    PolicyPayerEffective Date
    Surgical ProceduresUnitedHealthcare2026-09-01
    Outpatient Surgical Procedures - Site of ServiceUnitedHealthcare2026-09-01
    Site of Service Ambulatory Service Center (ASC) Select — Surgical or Diagnostic Procedures in AdultsPremera Bluecross2026-09-01
    Site of Service Ambulatory Surgical Center (ASC) Select — Surgical or Diagnostic Procedures in AdultsPremera Bluecross2026-09-01
    Site of Service Ambulatory Service Center (ASC) SelectPremera Bluecross2026-09-01
    Site of Service Ambulatory Surgical Center (ASC) Select — Site of Service for Ambulatory Surgical Procedures (ASC Select)Premera Bluecross2026-09-01
    Site of Service Ambulatory Service Center (ASC) SelectPremera Bluecross2026-09-01
    Outpatient Surgical Procedures - Site of Servicesierra health and life2026-08-01
    Medical Necessity Guidelines — Inpatient Surgical CareMass General Brigham Health Plan2026-08-01
    Ambulatory Surgery Center (ASC) - Site of Care PolicyKaiser Permanente2026-08-01

    Related Codes

    CPT-49180-PERCUTANEOUS-ABDOMINAL-NEEDLE-BIOPSY

    CPT 49180: Percutaneous Abdominal/Retroperitoneal Needle Biopsy

    CPT-49186-OPEN-ABDOMINAL-EXCISION-DESTRUCTION-SMALL-TUMORS-CYSTS

    CPT 49186: Open Excision/Destruction of Abdominal Tumors or Cysts ≤5 cm

    CPT-49187-OPEN-ABDOMINAL-TUMOR-CYST-EXCISION-5-1-10CM

    CPT 49187: Open Excision or Destruction of Abdominal Tumors/Cysts, 5.1–10 cm

    CPT-49188-OPEN-EXCISION-ABDOMINAL-TUMORS-10-1-20-CM

    CPT 49188: Open Abdominal Excision/Destruction of Tumor(s)/Cyst(s)

    CPT-49189-OPEN-ABDOMINAL-TUMOR-CYST-EXCISION-20-1-30CM

    CPT 49189: Open Excision/Destruction of Abdominal Tumors or Cysts (20.1–30 cm)

    CPT-49190-OPEN-ABDOMINAL-TUMOR-CYST-EXCISION-DESTRUCTION-OVER-30CM

    CPT 49190: Open Excision/Destruction of Abdominal Tumors or Cysts >30 cm

    CPT-49215-SACROCOCCYGEAL-MASS-EXCISION

    CPT 49215: Excision of Sacrococcygeal Tumor

    CPT-49250-UMBILICAL-EXCISION-HERNIA-INFECTION

    CPT 49250: Excision of Umbilicus (Umbilectomy)

    CPT-49255-OMENTECTOMY-FOR-METASTATIC-ABDOMINAL-PELVIC-CANCER

    CPT 49255: Omentectomy, Excision of Omentum for Metastatic Disease

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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