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    OpenPayerBilling CodesRepair Procedures on the PancreasCPT cpt-48548-pancreatic-jejunostomy-pancreatic-drainage
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    CPT 48548: Pancreaticojejunostomy for Pancreatic Drainage

    Medicare pays $1566 on average nationally for this procedure.

    CPT code 48548 describes a surgical pancreaticojejunostomy procedure in which the surgeon creates an anastomosis between the pancreas and the jejunum (second portion of the small intestine) to restore drainage of pancreatic secretions in the setting of chronic pancreatic inflammation or other pancreatic disease, performed as an open abdominal operative procedure; typical site of service is an inpatient or outpatient hospital operating room for general/abdominal surgery and service type is open pancreatic surgery for drainage and bypass.

    For related coverage guidance, see recent payer policy updates: Surgical Procedures, Outpatient Surgical Procedures - Site of Service, Site of Service Ambulatory Service Center (ASC) Select — Surgical or Diagnostic Procedures in Adults.

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    Table of contents

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    Clinical & Coding Specifications

    Clinical Context

    A typical patient is a 48-year-old male with long-standing alcohol-related chronic pancreatitis who presents with persistent upper abdominal pain, recurrent episodes of pancreatitis, and evidence of pancreatic ductal hypertension with dilatation on imaging. Despite optimized medical management and endoscopic interventions, the patient continues to have refractory pain and impaired quality of life. The surgical team evaluates the patient and elects to perform a pancreatojejunostomy to restore pancreatic drainage.

    Preoperative workflow includes history and physical, laboratory evaluation (including amylase, lipase, liver function tests), cross-sectional imaging (contrast-enhanced CT or MRCP) showing a dilated main pancreatic duct, and consultation with gastroenterology to document prior endoscopic attempts. Informed consent is obtained and anesthesia assessment performed. Intraoperative steps include midline or upper abdominal exposure, identification of the dilated pancreatic duct, longitudinal ductotomy, and creation of a jejunal Roux limb with a side-to-side or end-to-side anastomosis (pancreaticojejunostomy) to allow long-term ductal drainage. Postoperative workflow includes monitoring in a step-down or inpatient surgical unit, pain control, early ambulation, pancreatic enzyme and glycemic assessment, and discharge planning with outpatient surgical and gastroenterology follow-up. Typical length of inpatient stay is several days depending on recovery and complications.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    43281Removal of foreign body from esophagus; via flexible endoscopyMay be part of preoperative endoscopic interventions in patients with obstructing intraductal debris (used by gastroenterology prior to surgical drainage)
    43280Endoscopic retrograde cholangiopancreatography (ERCP) with stent placementPerformed preoperatively for ductal decompression or attempted therapy before 48548 is considered
    48100Pancreatectomy, totalRepresents a more extensive pancreatic resection that may be performed instead of drainage in selected cases
    47562Laparoscopy, surgical, cholecystectomyCholecystectomy may be performed concurrently if gallstone disease contributes to biliary or pancreatic pathology
    49002Reopening of recent laparotomy woundMay be used if re-exploration is required after complications from 48548

    Related Modifiers

    11 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    23Modifier -23 (Unusual Anesthesia) is used on anesthesia service CPT codes when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia…- Use modifier -23 only on anesthesia CPT codes (00100–01999) when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia because of…
    50Modifier –50 (Bilateral Procedure) is appended to a CPT code when an identical procedure is performed on paired anatomical structures during the same operative session. The AMA states to add…- Use modifier -50 when the same CPT surgical, diagnostic, or radiology procedure is performed on paired anatomical structures (both sides of the body) during the same operative/session by the same…
    51Modifier –51 (Multiple Procedures) is used when the same provider performs multiple procedures in the same session to identify secondary, non‑exempt procedures and indicate payment reduction logic…- Use modifier -51 when the same provider performs multiple distinct procedures during the same patient encounter: report the highest‑valued procedure first (no modifier) and append -51 to…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    59Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    66Modifier 66 (Surgical Team) is used when three or more surgeons act as primary surgeons on a single, highly complex procedure. The AMA defines it for use when a surgical team — often composed of…- Use modifier 66 when three or more surgeons act as primary surgeons working collaboratively as a surgical team on a single, highly complex or difficult procedure (for example organ…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…

    Showing 1–10 of 11

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    207K00000X
    2080P0006X
    208100000X
    364SA2200X
    207SG0205X
    208800000X
    207ZC0500X
    261QM1103X

    Related ICD-10-CM Codes

    21 rows

    ICD-10-CM CodeDescription
    C25.4Malignant neoplasm of endocrine pancreas
    C25.9Malignant neoplasm of pancreas, unspecified
    E10.9Type 1 diabetes mellitus without complications
    E11.9Type 2 diabetes mellitus without complications
    E86.0Dehydration
    K80.20Calculus of gallbladder without cholecystitis without obstruction
    K80.21Calculus of gallbladder without cholecystitis with obstruction
    K83.1Obstruction of bile duct
    K86.0Alcohol-induced chronic pancreatitis
    K86.1Other chronic pancreatitis

    Showing 1–10 of 21

    Related Payer Policy Updates

    Specialty: General Surgery1 / 3

    10 rows

    PolicyPayerEffective Date
    Surgical ProceduresUnitedHealthcare2026-09-01
    Outpatient Surgical Procedures - Site of ServiceUnitedHealthcare2026-09-01
    Site of Service Ambulatory Service Center (ASC) Select — Surgical or Diagnostic Procedures in AdultsPremera Bluecross2026-09-01
    Site of Service Ambulatory Surgical Center (ASC) Select — Surgical or Diagnostic Procedures in AdultsPremera Bluecross2026-09-01
    Site of Service Ambulatory Service Center (ASC) SelectPremera Bluecross2026-09-01
    Site of Service Ambulatory Surgical Center (ASC) Select — Site of Service for Ambulatory Surgical Procedures (ASC Select)Premera Bluecross2026-09-01
    Site of Service Ambulatory Service Center (ASC) SelectPremera Bluecross2026-09-01
    Outpatient Surgical Procedures - Site of Servicesierra health and life2026-08-01
    Medical Necessity Guidelines — Inpatient Surgical CareMass General Brigham Health Plan2026-08-01
    Ambulatory Surgery Center (ASC) - Site of Care PolicyKaiser Permanente2026-08-01

    Related Codes

    CPT-48500-PANCREATIC-CYST-MARSUPIALIZATION

    CPT 48500: Marsupialization of Pancreatic Cyst

    CPT-48510-OPEN-DRAINAGE-PANCREATIC-PSEUDOCYST

    CPT 48510: Open Drainage of Pancreatic Pseudocyst

    CPT-48520-PANCREATIC-CYST-ENTERIC-DRAINAGE

    CPT 48520: Pancreatic Cyst–Enteric Internal Drainage

    CPT-48540-PANCREATIC-CYST-INTERNAL-DRAINAGE-CYSTENTEROSTOMY

    CPT 48540: Pancreatic Cyst-Jejunostomy for Internal Drainage

    CPT-48545-PANCREAS-REPAIR-RECONSTRUCTION-TRAUMA

    CPT 48545: Repair and Reconstruction of Pancreas After Trauma

    CPT-48547-GASTRIC-TO-JEJUNUM-BYPASS-TRAUMATIC-ABDOMINAL-INJURY

    CPT 48547: Gastrojejunostomy to Bypass Duodenum for Traumatic Pancreatic Injury

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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