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    v1.0.30
    OpenPayerBilling CodesRepair Procedures on the PancreasCPT cpt-48510-open-drainage-pancreatic-pseudocyst
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    CPT 48510: Open Drainage of Pancreatic Pseudocyst

    Medicare pays $1053 on average nationally for this procedure.

    CPT code 48510 describes an open surgical procedure to access and drain a pancreatic pseudocyst using a formal incision; this is a surgical drainage service typically performed in an operating room or similar inpatient surgical setting for definitive management of symptomatic or complicated pseudocysts.

    For related coverage guidance, see recent payer policy updates: Surgical Procedures, Outpatient Surgical Procedures - Site of Service, Site of Service Ambulatory Service Center (ASC) Select — Surgical or Diagnostic Procedures in Adults.

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    Table of contents

    Progress1 / 7

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    Clinical & Coding Specifications

    Clinical Context

    A 54-year-old male with a history of chronic alcohol-related pancreatitis presents with progressive abdominal pain, early satiety, and weight loss. Cross-sectional imaging (contrast CT or MRI) demonstrates a large symptomatic pancreatic pseudocyst in the lesser sac measuring 8–12 cm with mass effect on the stomach and persistent symptoms despite conservative management and percutaneous aspiration attempt. The patient is assessed by a general surgeon and gastroenterologist; after multidisciplinary review, the decision is made to perform an open internal drainage procedure via laparotomy to create a cyst-gastrostomy (or cyst-jejunostomy) for definitive drainage.

    Preoperative workflow includes informed consent, NPO status, preoperative labs (CBC, CMP, coagulation studies), cross-sectional imaging review, and anesthesia evaluation. Intraoperative steps include exploratory laparotomy, identification and mobilization of the pseudocyst, evacuation of cyst contents, debridement of necrotic material if present, and creation of an anastomosis between the pseudocyst and a portion of the gastrointestinal tract (stomach or jejunum). Postoperative care includes monitoring in PACU or surgical floor, pain control, assessment for leak or bleeding, imaging if clinically indicated, and discharge planning with follow-up for nutrition and pancreatitis management. Typical sites of service are the inpatient operating room or an ambulatory surgical center capable of open abdominal surgery when medically appropriate. The service type is open surgical drainage of a pancreatic pseudocyst represented by 48510.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    48510Drainage of pancreatic pseudocyst via open incisionPrimary procedure describing open surgical internal or external drainage
    43282Endoscopic, transgastric or transduodenal drainage of pancreatic pseudocyst or pancreatic necrosis, with endoscopic ultrasound (EUS) guidanceAlternative, less invasive approach to internal drainage often considered before open surgery
    49322Laparoscopy, surgical; drainage of pancreatic pseudocystMinimally invasive surgical alternative to 48510 when feasible
    49406Placement of percutaneous drainage catheter for pancreatic or peripancreatic fluid collection (radiologic)Percutaneous drainage that may be performed as temporizing measure or prior to definitive open drainage
    43846Gastric bypass, nonmalabsorptive, with gastrojejunostomy (for context of internal anastomosis)Technique-related code representing creation of a cyst-enteric anastomosis conceptually similar to a cyst-jejunostomy — used here for procedural relationship, not as a substitute code
    49000Drainage of peritoneal abscess; without drainage by percutaneous catheterRelated intra-abdominal drainage procedures and postoperative management coding considerations

    Related Modifiers

    10 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    23Modifier -23 (Unusual Anesthesia) is used on anesthesia service CPT codes when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia…- Use modifier -23 only on anesthesia CPT codes (00100–01999) when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia because of…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    66Modifier 66 (Surgical Team) is used when three or more surgeons act as primary surgeons on a single, highly complex procedure. The AMA defines it for use when a surgical team — often composed of…- Use modifier 66 when three or more surgeons act as primary surgeons working collaboratively as a surgical team on a single, highly complex or difficult procedure (for example organ…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…
    80CPT® Modifier 80 (Assistant Surgeon) is appended to a surgical CPT code when a physician (MD or DO) provides full, continuous assistance throughout the operative procedure. It is intended only for…- Use CPT Modifier -80 when a physician (MD or DO) serves as an assistant surgeon and provides full, continuous assistance throughout the entire operative procedure; append -80 to the surgical CPT…
    81Modifier -81 indicates a physician served as a minimal assistant surgeon for part—not all—of an operative procedure. Use when a physician’s assisting role is limited and does not represent full…- Use CPT modifier -81 when a physician acts as a minimum assistant surgeon who assists during only part (a limited portion) of an operative procedure; append -81 to the primary surgical CPT code to…
    82Modifier 82 is appended to a surgical CPT code to indicate that an attending physician acted as an assistant because a qualified resident surgeon was unavailable. In teaching hospitals it documents…- When to use: Append modifier 82 in teaching-hospital settings to indicate a physician served as an assistant surgeon because a qualified resident surgeon was unavailable (includes situations where…

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    207P00000X
    208000000X
    207L00000X
    208100000X
    207K00000X
    103TA0700X
    261QA0600X
    246YC3302X

    Related ICD-10-CM Codes

    26 rows

    ICD-10-CM CodeDescription
    A09Infectious gastroenteritis and colitis, unspecified
    A41.9Sepsis, unspecified organism
    B95.61Methicillin susceptible Staphylococcus aureus infection as the cause of diseases classified elsewhere
    E86.0Dehydration
    I80.9Phlebitis and thrombophlebitis of unspecified site
    I82.90Acute embolism and thrombosis of unspecified vein
    K57.31Diverticulosis of large intestine without perforation or abscess with bleeding
    K68.11Postprocedural retroperitoneal abscess
    K74.60Unspecified cirrhosis of liver
    K75.9Inflammatory liver disease, unspecified

    Showing 1–10 of 26

    Related Payer Policy Updates

    Specialty: General Surgery1 / 3

    10 rows

    PolicyPayerEffective Date
    Surgical ProceduresUnitedHealthcare2026-09-01
    Outpatient Surgical Procedures - Site of ServiceUnitedHealthcare2026-09-01
    Site of Service Ambulatory Service Center (ASC) Select — Surgical or Diagnostic Procedures in AdultsPremera Bluecross2026-09-01
    Site of Service Ambulatory Surgical Center (ASC) Select — Surgical or Diagnostic Procedures in AdultsPremera Bluecross2026-09-01
    Site of Service Ambulatory Service Center (ASC) SelectPremera Bluecross2026-09-01
    Site of Service Ambulatory Surgical Center (ASC) Select — Site of Service for Ambulatory Surgical Procedures (ASC Select)Premera Bluecross2026-09-01
    Site of Service Ambulatory Service Center (ASC) SelectPremera Bluecross2026-09-01
    Outpatient Surgical Procedures - Site of Servicesierra health and life2026-08-01
    Medical Necessity Guidelines — Inpatient Surgical CareMass General Brigham Health Plan2026-08-01
    Ambulatory Surgery Center (ASC) - Site of Care PolicyKaiser Permanente2026-08-01

    Related Codes

    CPT-48500-PANCREATIC-CYST-MARSUPIALIZATION

    CPT 48500: Marsupialization of Pancreatic Cyst

    CPT-48520-PANCREATIC-CYST-ENTERIC-DRAINAGE

    CPT 48520: Pancreatic Cyst–Enteric Internal Drainage

    CPT-48540-PANCREATIC-CYST-INTERNAL-DRAINAGE-CYSTENTEROSTOMY

    CPT 48540: Pancreatic Cyst-Jejunostomy for Internal Drainage

    CPT-48545-PANCREAS-REPAIR-RECONSTRUCTION-TRAUMA

    CPT 48545: Repair and Reconstruction of Pancreas After Trauma

    CPT-48547-GASTRIC-TO-JEJUNUM-BYPASS-TRAUMATIC-ABDOMINAL-INJURY

    CPT 48547: Gastrojejunostomy to Bypass Duodenum for Traumatic Pancreatic Injury

    CPT-48548-PANCREATIC-JEJUNOSTOMY-PANCREATIC-DRAINAGE

    CPT 48548: Pancreaticojejunostomy for Pancreatic Drainage

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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