CPT code 43621 denotes a total gastrectomy with reconstruction by anastomosis of the distal small bowel to the stomach and is used to report surgical removal of the whole stomach with subsequent small-bowel anastomosis. This major abdominal operation has significant clinical and billing implications due to its complexity, typical inpatient setting, and perioperative resource needs. Nationally, accurate reporting of 43621 matters for surgical quality monitoring, hospital reimbursement, and tracking outcomes for complex gastric procedures.

Payors covered in this analysis include Aetna, Blue Cross Blue Shield, Cigna Health, UnitedHealthcare, and Medicare. Readers will find a concise overview of what the code represents, the clinical context in which it is used, and the typical sites of service. The publication provides benchmarks where available, summarizes relevant policy and coverage considerations, and outlines common billing and documentation themes associated with major abdominal resections. Data not available in the input is noted where applicable. This resource is intended for coding professionals, hospital billers, clinical leaders, and policy analysts seeking a national-level synthesis of CPT code 43621.