CPT code 43108 denotes removal of most or all of the esophagus via a non-thoracotomy approach with reconstruction using a small bowel or colon graft. This complex operative code captures high-acuity, resource-intensive care for patients with esophageal disease requiring esophageal resection and reconstruction. It is nationally relevant because it represents procedures with significant inpatient resource use, perioperative risk, and implications for surgical coding, case mix, and payment across major payers.

Key payers covered in this analysis include Aetna, Blue Cross Blue Shield, Cigna Health, UnitedHealthcare, and Medicare. Readers will find a concise overview of the clinical and coding context for CPT code 43108, benchmarks for utilization and payment where available, common billing and documentation considerations, and policy updates that affect coverage and coding practice. The publication also outlines expected sites of service and service type to assist clinical, coding, and revenue teams in classifying claims accurately.

Intended readers will gain a clear understanding of when CPT code 43108 applies, the clinical scope of the procedure, and the types of analyses and policy topics that commonly surround high-complexity esophagectomy claims. Data not available in the input will be noted where relevant.