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    OpenPayerBilling CodesExcision and Destruction Procedures on the Pharynx, Adenoids, and TonsilsCPT cpt-42808-pharyngeal-lesion-destruction-laser-cryosurgery
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    CPT 42808: Pharynx Lesion Destruction (Laser, Cryosurgery, Electrocautery)

    Medicare pays $242 on average nationally for this procedure.

    CPT code 42808 describes physician removal or destruction of a lesion of the pharynx using techniques such as laser (YAG, Argon), electrocautery, chemical agents, or cryosurgery/freezing (liquid nitrogen, carbon dioxide); this is an operative/ablative procedure typically performed by an otolaryngologist or head and neck surgeon in an outpatient surgical setting, ambulatory surgery center, or hospital operating room and is billed as a surgical lesion destruction of the pharyngeal mucosa.

    For related coverage guidance, see recent payer policy updates: Dental Anesthesia Services, Anesthesia Services for Interventional Pain Management Procedures in an Adult, General Anesthesia and Conscious Sedation Services.

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    Clinical & Coding Specifications

    Clinical Context

    A 56-year-old male presents to the otolaryngology clinic with progressive throat discomfort, intermittent odynophagia, and a persistent localized exophytic lesion on the posterior pharyngeal wall noted on flexible nasopharyngoscopy. Biopsy performed in clinic revealed a benign squamous papilloma with symptomatic bulk and intermittent bleeding. The planned procedure is removal/destruction of the pharyngeal lesion using laser ablation in the ambulatory surgery center under monitored anesthesia care. The clinical workflow includes preoperative evaluation, informed consent documenting risks of airway edema and bleeding, operating room setup with appropriate laser safety measures, direct laryngoscopy for visualization, lesion removal via laser (YAG) ablation with hemostasis via electrocautery as needed, specimen handling if excision is performed, post-anesthesia recovery, and discharge with instructions for voice rest, analgesia, and follow-up for pathology results and surveillance.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    31575Laryngoscopy, direct, with biopsyPerformed when tissue sampling of a pharyngeal or laryngeal lesion is required prior to or during lesion removal.
    31231Nasal/sinus endoscopy, diagnostic, unilateral or bilateralMay be performed preoperatively for comprehensive endoscopic airway and nasopharyngeal evaluation.
    42820Tonsillectomy, primary; younger than age 12Performed in patients requiring tonsillectomy when lesion involves tonsillar tissue; may be alternative to focal lesion destruction.
    31500Intubation, endotracheal, emergency and routineCommonly performed for airway control prior to operative removal of pharyngeal lesions under general anesthesia.
    31360Laryngoscopy, flexible or rigid, with removal of foreign bodyTechnique overlap when rigid instruments are used for removal/destruction of pharyngeal lesions.

    Related Modifiers

    10 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    59Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    63Modifier‑63 is appended to surgical CPT codes (20000–69990) when a procedure is performed on a neonate or infant weighing ≤ 4 kg (about 8.8 lbs). The AMA/AAPC definition specifies this use and notes…- Use modifier -63 only for surgical procedures in the CPT 20000–69990 series performed on a neonate or infant who weighs ≤ 4 kg at the time of the procedure; it indicates increased complexity due to…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…
    80CPT® Modifier 80 (Assistant Surgeon) is appended to a surgical CPT code when a physician (MD or DO) provides full, continuous assistance throughout the operative procedure. It is intended only for…- Use CPT Modifier -80 when a physician (MD or DO) serves as an assistant surgeon and provides full, continuous assistance throughout the entire operative procedure; append -80 to the surgical CPT…
    81Modifier -81 indicates a physician served as a minimal assistant surgeon for part—not all—of an operative procedure. Use when a physician’s assisting role is limited and does not represent full…- Use CPT modifier -81 when a physician acts as a minimum assistant surgeon who assists during only part (a limited portion) of an operative procedure; append -81 to the primary surgical CPT code to…
    26Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    207Y00000X
    208000000X
    363LF0000X
    2084P0800X
    163WS0200X
    376G00000X
    3336M0002X
    231HA2500X

    Related Payer Policy Updates

    Specialty: Anesthesiology1 / 3

    10 rows

    PolicyPayerEffective Date
    Dental Anesthesia ServicesProvidence Health Plan2026-10-01
    Anesthesia Services for Interventional Pain Management Procedures in an AdultCigna2026-09-15
    General Anesthesia and Conscious Sedation ServicesUnitedHealthcare2026-09-01
    Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use DisordersPremera Bluecross2026-07-01
    Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use DisordersPremera Bluecross2026-07-01
    Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use DisordersPremera Bluecross2026-07-01
    Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use DisordersPremera Bluecross2026-07-01
    Elective Inpatient Services (for Idaho Only)UnitedHealthcare2026-06-01
    Sites of Servicepriority health2026-06-01
    Coverage for Ambulatory Surgery Unit (ASU)/Outpatient Facility and Anesthesia for Dental Servicesuniverahealthcare2026-05-21

    Related Codes

    CPT-42800-OROPHARYNGEAL-BIOPSY

    CPT 42800: Biopsy, Oropharynx

    CPT-42804-NASOPHARYNGEAL-LESION-BIOPSY

    CPT 42804: Biopsy of Visible Nasopharyngeal Lesion

    CPT-42806-NASOPHARYNGEAL-BIOPSY-UNKNOWN-PRIMARY-LESION

    CPT 42806: Biopsy of Nasopharyngeal Lesion, Unknown Primary

    CPT-42809-PHARYNX-FOREIGN-BODY-REMOVAL

    CPT 42809: Removal of Foreign Body from Pharynx

    CPT-42810-BRACHIAL-CLEFT-CYST-EXCISION

    CPT 42810: Excision of Brachial Cleft Cyst, Lateral Neck

    CPT-42815-BRACHIAL-CLEFT-CYST-EXCISION

    CPT 42815: Excision of Brachial Cleft Cyst, Lateral Neck

    CPT-42820-TONSILLECTOMY-AND-ADENOIDECTOMY-YOUNGER-THAN-12

    CPT 42820: Tonsillectomy and Adenoidectomy, Patient Younger Than 12 Years

    CPT-42821-TONSILLECTOMY-ADENOIDECTOMY-AGE-12-PLUS

    CPT 42821: Tonsillectomy with Adenoidectomy, Age 12 or Older

    CPT-42825-PEDIATRIC-TONSILLECTOMY-UNDER-12

    CPT 42825: Tonsillectomy in Patients Under 12 Years

    CPT-42826-TONSILLECTOMY-AGE-12-AND-OLDER

    CPT 42826: Tonsillectomy for Patients Age 12 and Older

    Showing 1–10 of 22

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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