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    OpenPayerBilling CodesExcision and Destruction Procedures on the Palate and UvulaCPT cpt-42107-palate-uvula-lesion-excision-local-flap
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    CPT 42107: Excision of Palate or Uvula Lesion with Local Flap Closure

    Medicare pays $486 on average nationally for this procedure.

    CPT code 42107 describes surgical excision of a lesion on the palate or uvula with closure of the defect using a local flap; this is a minor oral surgical procedure typically performed by an otolaryngologist or oral/maxillofacial surgeon in an ambulatory surgery center or hospital outpatient setting and is classified as a wound excision and reconstruction service for lesion removal on intraoral soft tissue.

    For related coverage guidance, see recent payer policy updates: Dental Anesthesia Services, Anesthesia Services for Interventional Pain Management Procedures in an Adult, General Anesthesia and Conscious Sedation Services.

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    Table of contents

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    Clinical & Coding Specifications

    Clinical Context

    A 54-year-old patient presents with a symptomatic, enlarging mucosal lesion on the soft palate causing dysphagia and intermittent bleeding. After clinical evaluation and possible biopsy confirming a benign or early malignant pathology, the otolaryngology or oral and maxillofacial surgery team schedules an excisional procedure. In the operating room under monitored anesthesia care or general anesthesia, the surgeon excises the lesion from the palate or uvula and performs local tissue mobilization to create a flap and close the defect primarily. Typical perioperative workflow includes preoperative assessment, informed consent documenting lesion location and flap closure, intraoperative specimen handling for pathology, hemostasis, layered closure with a local flap, and postoperative instructions for oral care and activity restriction. Typical site of service is an ambulatory surgery center or hospital outpatient operating room. Service type is a surgical excision with local flap closure of a lesion of the palate or uvula, classified as an outpatient surgical procedure involving the oral cavity/ oropharynx.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    31360Palatoplasty for velopharyngeal insufficiency; primary repairPerformed for functional palatal reconstruction and may be performed in patients needing additional palatal repair beyond lesion excision.
    41512Excision of lesion of soft palate; complicatedUsed for larger or more complex excisions of the soft palate; may be an alternative or adjunct when more extensive resection is required.
    40490Excision of benign tumor or cyst of lip, mucosa or vestibule; complicatedRepresents comparable oral mucosal excision techniques and may be performed in the same session for separate lesions.
    88305Level IV surgical pathology, gross and microscopic examinationUsed for histopathologic examination of the excised specimen; often billed by pathology to confirm diagnosis.
    99143Moderate sedation services provided by the same physician performing the procedure (list separately in addition to procedure)May be used if moderate sedation is administered by the proceduralist for comfort during excision when documentation supports separate billing.

    Related Modifiers

    11 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    23Modifier -23 (Unusual Anesthesia) is used on anesthesia service CPT codes when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia…- Use modifier -23 only on anesthesia CPT codes (00100–01999) when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia because of…
    26Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
    50Modifier –50 (Bilateral Procedure) is appended to a CPT code when an identical procedure is performed on paired anatomical structures during the same operative session. The AMA states to add…- Use modifier -50 when the same CPT surgical, diagnostic, or radiology procedure is performed on paired anatomical structures (both sides of the body) during the same operative/session by the same…
    51Modifier –51 (Multiple Procedures) is used when the same provider performs multiple procedures in the same session to identify secondary, non‑exempt procedures and indicate payment reduction logic…- Use modifier -51 when the same provider performs multiple distinct procedures during the same patient encounter: report the highest‑valued procedure first (no modifier) and append -51 to…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    66Modifier 66 (Surgical Team) is used when three or more surgeons act as primary surgeons on a single, highly complex procedure. The AMA defines it for use when a surgical team — often composed of…- Use modifier 66 when three or more surgeons act as primary surgeons working collaboratively as a surgical team on a single, highly complex or difficult procedure (for example organ…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…

    Showing 1–10 of 11

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    231HA2400X
    225CA2400X
    243U00000X
    1710I1003X
    202K00000X
    183500000X
    163WG0600X
    322D00000X

    Related Payer Policy Updates

    Specialty: Anesthesiology1 / 3

    10 rows

    PolicyPayerEffective Date
    Dental Anesthesia ServicesProvidence Health Plan2026-10-01
    Anesthesia Services for Interventional Pain Management Procedures in an AdultCigna2026-09-15
    General Anesthesia and Conscious Sedation ServicesUnitedHealthcare2026-09-01
    Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use DisordersPremera Bluecross2026-07-01
    Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use DisordersPremera Bluecross2026-07-01
    Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use DisordersPremera Bluecross2026-07-01
    Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use DisordersPremera Bluecross2026-07-01
    Elective Inpatient Services (for Idaho Only)UnitedHealthcare2026-06-01
    Sites of Servicepriority health2026-06-01
    Coverage for Ambulatory Surgery Unit (ASU)/Outpatient Facility and Anesthesia for Dental Servicesuniverahealthcare2026-05-21

    Related Codes

    CPT-42100-PALATE-UVULA-TISSUE-REMOVAL-PATHOLOGY

    CPT 42100: Excision of Palate or Uvula Tissue for Pathology

    CPT-42104-PALATE-UVULA-LESION-EXCISION-NO-CLOSURE

    CPT 42104: Excision of Lesion from Palate or Uvula, No Closure

    CPT-42106-PALATE-UVULA-LESION-EXCISION-SIMPLE-REPAIR

    CPT 42106: Excision of Lesion, Palate or Uvula; Simple Repair

    CPT-42120-PALATAL-LESION-RESECTION-WIDE-AREA

    CPT 42120: Wide Resection of Palatal/Oral Lesion

    CPT-42140-UVULOPALATOPHARYNGOPLASTY-UVULA-REMOVAL

    CPT 42140: Uvula Removal for Snoring

    CPT-42145-PALATOPHARYNGOPLASTY-UVULOPALATOPHARYNGOPLASTY

    CPT 42145: Palatopharyngoplasty for Oropharyngeal Airway Widening

    CPT-42160-PALATE-UVULA-LESION-DESTRUCTION

    CPT 42160: Destruction of Lesion on Palate or Uvula

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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