CPT code 42106 denotes excision of a lesion from the palate or uvula with simple repair. This surgical code captures a targeted head and neck soft-tissue procedure commonly performed in ambulatory surgical centers, hospital outpatient departments, and some office-based surgical settings. Nationally, accurate coding of 42106 matters for appropriate procedural reporting, clinical documentation alignment, and payment consistency for otolaryngology and oral maxillofacial services.

Key payers discussed include Aetna, Blue Cross Blue Shield, Cigna Health, UnitedHealthcare, and Medicare. Readers will find a concise explanation of the clinical service represented by the code, the typical sites of service, and the role this procedure plays in head and neck care pathways. The publication also summarizes common billing considerations and benchmarks where available, highlights relevant policy or coding clarifications, and provides clinical context to inform documentation and charge capture. Data not available in the input is noted where applicable, and the content is presented for a national audience without state-specific detail.