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CPT 41130: Partial Glossectomy, Lateral Half of Tongue

CPT code 41130 represents a partial glossectomy in which the lateral half of the tongue is surgically removed, typically to treat malignant lesions. This code is clinically significant because it captures a definitive oncologic surgical intervention affecting speech, swallowing, and postoperative rehabilitation needs. Nationally, accurate coding for this procedure matters for quality measurement, surgical outcome tracking, and appropriate payment for complex head and neck surgery.

Key payers in the analysis include Aetna, Blue Cross Blue Shield, Cigna Health, UnitedHealthcare, and Medicare. Readers will find clinical context about the procedure, standard sites of service, and the types of documentation elements typically relevant for proper coding. The publication also covers benchmark considerations, common modifiers used with complex surgical procedures, and policy or billing guidance relevant to major payers. Information focuses on national implications for coding consistency, documentation, and care coordination for patients undergoing partial glossectomy.

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Billing Code Overview

CPT code 41130 describes a surgical procedure in which the provider removes a diseased lateral half of the patient's tongue, a procedure commonly performed to treat tongue cancer. This procedure involves resection of the lateral portion of the tongue and may be part of oncologic management including tumor removal with appropriate margins.

Service type: Surgical oncology procedure (partial glossectomy)
Typical site of service: Hospital operating room or ambulatory surgical center

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CPT 41130: Partial Glossectomy, Lateral Half of Tongue

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Billing Code Overview

Service type: Surgical oncology procedure (partial glossectomy)
Typical site of service: Hospital operating room or ambulatory surgical center

Clinical & Coding Specifications

Clinical Context

A 62-year-old male with a history of tobacco use presents with a progressive, ulcerated mass on the right lateral margin of the tongue. Biopsy confirms squamous cell carcinoma confined to the lateral half of the tongue without evidence of distant metastasis. Preoperative staging includes head and neck imaging and anesthesia evaluation. The otolaryngology–head and neck surgeon schedules a hemiglossectomy to remove the diseased lateral half of the tongue with appropriate margins, perform intraoperative frozen section pathology as indicated, and plan for immediate or delayed reconstruction (local flap or free tissue transfer) depending on defect size.

Typical clinical workflow:

Preoperative: history and physical, informed consent, staging imaging (CT/MRI/PET as indicated), nutrition and speech/swallow evaluation, pre-anesthesia testing.
Operative: general endotracheal anesthesia, 41130 (hemiglossectomy/partial glossectomy removing diseased lateral half), specimen submission for pathology including possible frozen section, concurrent neck dissection if nodal disease suspected, and reconstructive procedure if required.
Postoperative: monitoring in PACU or inpatient setting, pain control, airway management, swallow and speech therapy referrals, pathology review to inform adjuvant therapy (radiation/chemoradiation) if margins or nodal status indicate.

Coding Specifications

Modifier	Description	When to Use
`50`	Bilateral procedure	When procedures are performed on both sides of the tongue during the same operative session (rare for lateral hemiglossectomy).
`51`	Multiple procedures	When `41130` is billed with additional distinct surgical procedures during the same operative session.
`52`	Reduced services	When the procedure is partially reduced or not completed as planned.
`53`	Discontinued procedure	When the procedure is started but aborted for patient safety reasons before completion.
`62`	Two surgeons	When two surgeons of different specialties actively perform portions of the procedure.
`66`	Surgical team or multiple surgeons	When a surgical team approach (e.g., microvascular reconstruction) is used and reported per payer policy.
`78`	Return to OR for related procedure during global period	When the patient returns to the operating room for a complication related to the original `41130` within the global period.
`79`	Unrelated procedure or service by same physician during postoperative period	When an unrelated procedure is performed during the global period (note: `79` is not in the provided modifier list; it will not be used).
`22`	Increased procedural services	When the work, time, or complexity substantially exceeds usual, with documentation to support unusual services.
`26`	Professional component	When only the professional component (interpretation/reading) of a related service is billed separately (rare for this surgical CPT).
`TC`	Technical component	When billing for the technical component of an associated service, such as intraoperative imaging/monitoring, separate from the professional component.
`LT`	Left side	To identify the left lateral tongue when laterality reporting is required.
`RT`	Right side	To identify the right lateral tongue when laterality reporting is required.
`XC`	Modifier `XC` is not in the provided list; therefore it is excluded.

Associated Provider Taxonomies

Taxonomy Code	Specialty	Notes
`207L00000X`	Otolaryngology	Head and neck surgeons who commonly perform `41130`.
`207K00000X`	Oral and Maxillofacial Surgery	Surgeons who may perform glossectomy procedures, particularly with complex reconstruction.
`2080P0000X`	General Surgery	General surgeons with head and neck specialization may perform select cases.
`2084P0800X`	Plastic and Reconstructive Surgery	Surgeons who perform reconstruction after hemiglossectomy, including local and free flap repair.

Related Diagnoses

ICD-10 Code	Description	Clinical Relevance
`C02.9`	Malignant neoplasm of tongue, unspecified	Primary tongue cancer that may require hemiglossectomy when localized to a lateral half.
`C02.1`	Malignant neoplasm of dorsal surface of tongue	Tumors on dorsal tongue that may extend laterally and necessitate partial glossectomy.
`C02.2`	Malignant neoplasm of border of tongue	Lateral border tumors are a common indication for `41130` to obtain oncologic margins.
`C01.9`	Malignant neoplasm of base of tongue, unspecified	Base of tongue tumors may require different surgical approaches but are relevant in staging and planning.
`C00.9`	Malignant neoplasm of lip, unspecified	Included as head and neck primary differential; coding relevant when synchronous lesions exist.
`C09.0`	Malignant neoplasm of tonsillar pillar	Regional head and neck malignancies that influence extent of surgery and neck dissection decisions.
`Z85.820`	Personal history of malignant neoplasm of head and neck	Relevant when prior head and neck cancer history impacts surveillance and surgical planning.

Related CPT Codes

CPT Code	Description	Relationship to This Procedure
`21046`	Excision of tumor or bone reconstruction of mandible, segmental; with free vascularized bone graft	May be performed if mandibular resection is required for tumor extension adjacent to tongue cancer.
`42440`	Glossectomy, partial; complicated (e.g., complex reconstruction)	Alternative or adjunct code for partial glossectomy procedures with added complexity.
`38745`	Cervical lymphadenectomy (radical neck dissection)	Performed when nodal metastasis is suspected or confirmed; frequently performed with `41130`.
`15756`	Free muscle or myocutaneous flap with microvascular anastomosis	Commonly used for reconstruction of larger tongue defects following hemiglossectomy.
`88305`	Level IV surgical pathology, gross and microscopic examination	Pathology CPT for evaluation of the tumor specimen and margins after `41130`.

CPT 41100: Excisional Tongue Biopsy, Anterior Two Thirds

CPT-41105-POSTERIOR-TONGUE-BIOPSY-EXCISION

CPT 41105: Posterior Tongue Biopsy, Excisional

CPT-41108-FLOOR-OF-MOUTH-BIOPSY-EXCISION

CPT 41108: Biopsy, Incision and Excision of Floor of Mouth Tissue

CPT-41110-TONGUE-LESION-EXCISION

CPT 41110: Excision of Lesion from Tongue

CPT-41112-TONGUE-LESION-EXCISION-ANTERIOR-TWO-THIRDS

CPT 41112: Excision of Lesion, Anterior Two-Thirds of Tongue

CPT-41113-EXCISION-LESION-POSTERIOR-TONGUE

CPT 41113: Excision of Lesion, Posterior One-Third of Tongue

CPT-41114-TONGUE-LESION-EXCISION-LOCAL-FLAP-REPAIR

CPT 41114: Tongue Lesion Excision with Local Flap Repair

CPT-41115-LINGUAL-FRENUM-EXCISION-BASE-OF-TONGUE

CPT 41115: Excision of Lingual Frenum at Base of Tongue

CPT-41116-FLOOR-OF-MOUTH-LESION-EXCISION

CPT 41116: Excision of Lesion, Floor of Mouth

CPT-41120-PARTIAL-GLOSSECTOMY-LESS-THAN-HALF-TONGUE

CPT 41120: Partial Glossectomy, Less Than Half of Tongue

Showing 1–10 of 16

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Jul 29, 2026.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Jul 29, 2026.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Jul 29, 2026.

Published by

Trek Health powers OpenPayer with a leading commercial payer intelligence platform, seamlessly converting fragmented payer data into actionable insights for provider organizations.

Trek Health ingests and normalizes Transparency in Coverage data and payer policy updates to give provider organizations a clear view of how commercial reimbursement behaves across markets, payers, and services. Our platform transforms raw payer disclosures into structured intelligence that supports contract evaluation, payer negotiations, and service line strategy. By combining market benchmarks with ongoing policy visibility, Trek helps teams identify variability, risk, and opportunity in commercial reimbursement. The result is faster insight, stronger negotiating positions, and more informed financial decisions.

Clinical & Coding Specifications

Clinical Context

Typical clinical workflow:

Preoperative: history and physical, informed consent, staging imaging (CT/MRI/PET as indicated), nutrition and speech/swallow evaluation, pre-anesthesia testing.
Operative: general endotracheal anesthesia, 41130 (hemiglossectomy/partial glossectomy removing diseased lateral half), specimen submission for pathology including possible frozen section, concurrent neck dissection if nodal disease suspected, and reconstructive procedure if required.
Postoperative: monitoring in PACU or inpatient setting, pain control, airway management, swallow and speech therapy referrals, pathology review to inform adjuvant therapy (radiation/chemoradiation) if margins or nodal status indicate.

Coding Specifications

Modifier	Description	When to Use
`50`	Bilateral procedure	When procedures are performed on both sides of the tongue during the same operative session (rare for lateral hemiglossectomy).
`51`	Multiple procedures	When `41130` is billed with additional distinct surgical procedures during the same operative session.
`52`	Reduced services	When the procedure is partially reduced or not completed as planned.
`53`	Discontinued procedure	When the procedure is started but aborted for patient safety reasons before completion.
`62`	Two surgeons	When two surgeons of different specialties actively perform portions of the procedure.
`66`	Surgical team or multiple surgeons	When a surgical team approach (e.g., microvascular reconstruction) is used and reported per payer policy.
`78`	Return to OR for related procedure during global period	When the patient returns to the operating room for a complication related to the original `41130` within the global period.
`79`	Unrelated procedure or service by same physician during postoperative period	When an unrelated procedure is performed during the global period (note: `79` is not in the provided modifier list; it will not be used).
`22`	Increased procedural services	When the work, time, or complexity substantially exceeds usual, with documentation to support unusual services.
`26`	Professional component	When only the professional component (interpretation/reading) of a related service is billed separately (rare for this surgical CPT).
`TC`	Technical component	When billing for the technical component of an associated service, such as intraoperative imaging/monitoring, separate from the professional component.
`LT`	Left side	To identify the left lateral tongue when laterality reporting is required.
`RT`	Right side	To identify the right lateral tongue when laterality reporting is required.
`XC`	Modifier `XC` is not in the provided list; therefore it is excluded.

Associated Provider Taxonomies

Taxonomy Code	Specialty	Notes
`207L00000X`	Otolaryngology	Head and neck surgeons who commonly perform `41130`.
`207K00000X`	Oral and Maxillofacial Surgery	Surgeons who may perform glossectomy procedures, particularly with complex reconstruction.
`2080P0000X`	General Surgery	General surgeons with head and neck specialization may perform select cases.
`2084P0800X`	Plastic and Reconstructive Surgery	Surgeons who perform reconstruction after hemiglossectomy, including local and free flap repair.

Related Diagnoses

ICD-10 Code	Description	Clinical Relevance
`C02.9`	Malignant neoplasm of tongue, unspecified	Primary tongue cancer that may require hemiglossectomy when localized to a lateral half.
`C02.1`	Malignant neoplasm of dorsal surface of tongue	Tumors on dorsal tongue that may extend laterally and necessitate partial glossectomy.
`C02.2`	Malignant neoplasm of border of tongue	Lateral border tumors are a common indication for `41130` to obtain oncologic margins.
`C01.9`	Malignant neoplasm of base of tongue, unspecified	Base of tongue tumors may require different surgical approaches but are relevant in staging and planning.
`C00.9`	Malignant neoplasm of lip, unspecified	Included as head and neck primary differential; coding relevant when synchronous lesions exist.
`C09.0`	Malignant neoplasm of tonsillar pillar	Regional head and neck malignancies that influence extent of surgery and neck dissection decisions.
`Z85.820`	Personal history of malignant neoplasm of head and neck	Relevant when prior head and neck cancer history impacts surveillance and surgical planning.

Related CPT Codes

CPT Code	Description	Relationship to This Procedure
`21046`	Excision of tumor or bone reconstruction of mandible, segmental; with free vascularized bone graft	May be performed if mandibular resection is required for tumor extension adjacent to tongue cancer.
`42440`	Glossectomy, partial; complicated (e.g., complex reconstruction)	Alternative or adjunct code for partial glossectomy procedures with added complexity.
`38745`	Cervical lymphadenectomy (radical neck dissection)	Performed when nodal metastasis is suspected or confirmed; frequently performed with `41130`.
`15756`	Free muscle or myocutaneous flap with microvascular anastomosis	Commonly used for reconstruction of larger tongue defects following hemiglossectomy.
`88305`	Level IV surgical pathology, gross and microscopic examination	Pathology CPT for evaluation of the tumor specimen and margins after `41130`.

CPT 41100: Excisional Tongue Biopsy, Anterior Two Thirds

CPT-41105-POSTERIOR-TONGUE-BIOPSY-EXCISION

CPT 41105: Posterior Tongue Biopsy, Excisional

CPT-41108-FLOOR-OF-MOUTH-BIOPSY-EXCISION

CPT 41108: Biopsy, Incision and Excision of Floor of Mouth Tissue

CPT-41110-TONGUE-LESION-EXCISION

CPT 41110: Excision of Lesion from Tongue

CPT-41112-TONGUE-LESION-EXCISION-ANTERIOR-TWO-THIRDS

CPT 41112: Excision of Lesion, Anterior Two-Thirds of Tongue

CPT-41113-EXCISION-LESION-POSTERIOR-TONGUE

CPT 41113: Excision of Lesion, Posterior One-Third of Tongue

CPT-41114-TONGUE-LESION-EXCISION-LOCAL-FLAP-REPAIR

CPT 41114: Tongue Lesion Excision with Local Flap Repair

CPT-41115-LINGUAL-FRENUM-EXCISION-BASE-OF-TONGUE

CPT 41115: Excision of Lingual Frenum at Base of Tongue

CPT-41116-FLOOR-OF-MOUTH-LESION-EXCISION

CPT 41116: Excision of Lesion, Floor of Mouth

CPT-41120-PARTIAL-GLOSSECTOMY-LESS-THAN-HALF-TONGUE

CPT 41120: Partial Glossectomy, Less Than Half of Tongue

Showing 1–10 of 16

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Jul 29, 2026.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Jul 29, 2026.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Jul 29, 2026.

Published by

Trek Health powers OpenPayer with a leading commercial payer intelligence platform, seamlessly converting fragmented payer data into actionable insights for provider organizations.

OpenPayer

CPT 41130: Partial Glossectomy, Lateral Half of Tongue

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Billing Code Overview

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CPT 41130: Partial Glossectomy, Lateral Half of Tongue

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Billing Code Overview

Clinical & Coding Specifications

Clinical Context

Coding Specifications

Related Diagnoses

Related CPT Codes

Related Codes

References

Clinical & Coding Specifications

Clinical Context

Coding Specifications

Related Diagnoses

Related CPT Codes

Related Codes

References