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    v1.0.30
    OpenPayerBilling CodesExcision Procedures on the Tongue and Floor of MouthCPT cpt-41105-posterior-tongue-biopsy-excision
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    CPT 41105: Partial Excision/Biopsy of Posterior Tongue

    Medicare pays $196 on average nationally for this procedure.

    CPT code 41105 describes a surgical biopsy procedure in which the provider makes an incision in the posterior one-third of the tongue and excises affected tissue for diagnostic biopsy; service type: surgical oral biopsy; typical site of service: ambulatory surgical center or hospital outpatient setting (oral cavity/oropharynx procedure).

    For related coverage guidance, see recent payer policy updates: Orthopedic Joint Procedures of the Knee for Managed Medicaid (MMC), Health and Recovery Plan (HARP), Child Health Plus (CHP), and Essential Plan (EP) Members, Autologous Chondrocyte Transplantation or Implantation Corporate Medical Policy, Autologous Platelet-Derived Growth Factors (Platelet-Rich Plasma [PRP]).

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    Table of contents

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    Clinical & Coding Specifications

    Clinical Context

    A 62-year-old male presents to the otolaryngology clinic with a 4-week history of persistent throat pain and a non-healing ulcer on the posterior one-third of the tongue noted on exam. The surgeon performs a focused procedure under local anesthesia with monitored sedation in an outpatient minor procedure room: a posterior tongue incision and excisional biopsy of the suspicious lesion to establish histopathology. The workflow includes pre-procedure consent and history, review of anticoagulation, marking the lesion, administration of local anesthetic (or conscious sedation if clinically indicated), incision in the posterior tertiary tongue tissue, excision of the targeted tissue for biopsy, hemostasis, specimen labeling and submission to pathology, brief recovery monitoring, and discharge with wound care instructions and follow-up to review pathology results.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    40105Data not available in the input.Data not available in the input.
    40490Data not available in the input.Data not available in the input.
    42820Excision of lesion of the anterior tongue; superficialMay be used for lesions located on the anterior tongue rather than posterior one-third; alternative anatomic code.
    42821Partial glossectomy, unilateral; anterior two-thirdsMore extensive resection when a larger portion of the tongue requires removal after diagnostic findings.
    20220Biopsy, soft tissue of the head and neckMay be used for non-tongue soft tissue biopsies in the head and neck region performed in the same clinical episode.

    Related Modifiers

    12 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    25CPT modifier 25 indicates that on the same day as another procedure or service, the same physician or other qualified health care professional provided a significant, separately identifiable…- When to apply: Use modifier 25 only on an E/M code to indicate the same provider delivered a significant, separately identifiable E/M service on the same day as another procedure or service — i.e.,…
    26Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
    51Modifier –51 (Multiple Procedures) is used when the same provider performs multiple procedures in the same session to identify secondary, non‑exempt procedures and indicate payment reduction logic…- Use modifier -51 when the same provider performs multiple distinct procedures during the same patient encounter: report the highest‑valued procedure first (no modifier) and append -51 to…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    59Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    66Modifier 66 (Surgical Team) is used when three or more surgeons act as primary surgeons on a single, highly complex procedure. The AMA defines it for use when a surgical team — often composed of…- Use modifier 66 when three or more surgeons act as primary surgeons working collaboratively as a surgical team on a single, highly complex or difficult procedure (for example organ…
    73Modifier 73 indicates a facility-level outpatient hospital or ASC procedure that was discontinued after the patient was prepared and taken to the procedure/operating room but before any anesthesia…- When to use: Apply CPT modifier 73 on the FACILITY (outpatient hospital or ASC) claim when the patient has been fully prepared and physically taken into the procedure/operating room but the…

    Showing 1–10 of 12

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    207Y00000X
    2080P0207X
    208100000X
    207RH0000X
    2084P0015X
    231HA2500X
    261QR0206X
    171100000X

    Related ICD-10-CM Codes

    28 rows

    ICD-10-CM CodeDescription
    C02.0Malignant neoplasm of dorsal surface of tongue
    C02.1Malignant neoplasm of border of tongue
    C02.2Malignant neoplasm of ventral surface of tongue
    C02.3Malignant neoplasm of anterior two-thirds of tongue, part unspecified
    C02.8Malignant neoplasm of overlapping sites of tongue
    C02.9Malignant neoplasm of tongue, unspecified
    C06.9Malignant neoplasm of mouth, unspecified
    C09.0Malignant neoplasm of tonsillar fossa
    C09.1Malignant neoplasm of tonsillar pillar (anterior) (posterior)
    C09.8Malignant neoplasm of overlapping sites of tonsil

    Showing 1–10 of 28

    Related Payer Policy Updates

    Specialty: Orthopedics/Musculoskeletal1 / 2

    10 rows

    PolicyPayerEffective Date
    Orthopedic Joint Procedures of the Knee for Managed Medicaid (MMC), Health and Recovery Plan (HARP), Child Health Plus (CHP), and Essential Plan (EP) Membersuniverahealthcare2027-01-01
    Autologous Chondrocyte Transplantation or Implantation Corporate Medical Policybcbsvermont2026-12-01
    Autologous Platelet-Derived Growth Factors (Platelet-Rich Plasma [PRP])Cigna2026-10-15
    Metatarsophalangeal Joint ReplacementCigna2026-10-15
    Shoulder Arthroplasty (Total, Partial, Reverse, Revision and Resurfacing)univerahealthcare2026-10-15
    Hip Arthroplasty (partial and total hip replacement)univerahealthcare2026-10-15
    Artificial Lumbar Intervertebral Disc (Lumbar Total Disc Arthroplasty)univerahealthcare2026-10-15
    Osteochondral Grafting of the Kneeuniverahealthcare2026-10-15
    Lumbar Fusion (arthrodesis) with decompressionuniverahealthcare2026-10-15
    Metal-on-Metal Total Hip Resurfacinguniverahealthcare2026-10-15

    Related Codes

    CPT-41100-TONGUE-EXCISIONAL-BIOPSY-ANTERIOR-TWO-THIRDS

    CPT 41100: Partial Glossectomy for Biopsy, Anterior Tongue

    CPT-41108-FLOOR-OF-MOUTH-BIOPSY-EXCISION

    CPT 41108: Incision and Excision of Tissue, Floor of Mouth for Biopsy

    CPT-41110-TONGUE-LESION-EXCISION

    CPT 41110: Excision of Lesion of Tongue

    CPT-41112-TONGUE-LESION-EXCISION-ANTERIOR-TWO-THIRDS

    CPT 41112: Excision of Lesion, Anterior Two-Thirds of Tongue

    CPT-41113-EXCISION-LESION-POSTERIOR-TONGUE

    CPT 41113: Excision of Lesion, Posterior One Third of Tongue

    CPT-41114-TONGUE-LESION-EXCISION-LOCAL-FLAP-REPAIR

    CPT 41114: Excision of Tongue Lesion with Local Flap Repair

    CPT-41115-LINGUAL-FRENUM-EXCISION-BASE-OF-TONGUE

    CPT 41115: Frenulectomy, Excision of Lingual Frenum

    CPT-41116-FLOOR-OF-MOUTH-LESION-EXCISION

    CPT 41116: Excision of Lesion, Floor of Mouth

    CPT-41120-PARTIAL-GLOSSECTOMY-LESS-THAN-HALF-TONGUE

    CPT 41120: Partial Glossectomy, Less Than Half of Tongue

    CPT-41130-PARTIAL-GLOSSECTOMY-LATERAL-TONGUE-RESECTION

    CPT 41130: Partial Glossectomy, Lateral Half of Tongue

    Showing 1–10 of 16

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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