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    v1.0.30
    OpenPayerBilling CodesIncision Procedures on the Accessory SinusesCPT cpt-31050-sphenoid-sinus-incision-biopsy
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    CPT 31050: Sphenoid Sinus Incision with Possible Biopsy

    Medicare pays $491 on average nationally for this procedure.

    CPT code 31050 describes a surgical procedure involving an incision into the sphenoid sinus, often performed endoscopically, and may include biopsy of sphenoid sinus tissue; this is an intranasal sinus surgery typically furnished as an operating room or procedure room service within an ear, nose, and throat (ENT) or otolaryngology clinical setting.

    For related coverage guidance, see recent payer policy updates: Office-based Laryngeal Procedures, Injectable Dermal Fillers and Bulking Agents (for New Mexico Only), Injectable Dermal Fillers and Bulking Agents (for Kentucky Only).

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    Table of contents

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    Clinical & Coding Specifications

    Clinical Context

    A typical patient is an adult presenting with persistent or recurrent sphenoid sinus symptoms such as deep-seated headache behind the eyes, purulent nasal drainage, postnasal drip, or cranial neuropathy when imaging (CT or MRI) demonstrates opacification, mucosal thickening, or a suspicious lesion within the sphenoid sinus. The procedure 31050 (sphenoidotomy with possible biopsy) is performed by an otolaryngologist or rhinologist in an operating room or ambulatory surgical center under monitored anesthesia care or general anesthesia. Preoperative workflow includes history and physical, nasal endoscopy, sinus CT review, informed consent documenting risks (bleeding, CSF leak, vision change), and necessary preop labs or anticoagulation management. Intraoperative steps commonly include nasal decongestion, endoscopic visualization of the sphenoethmoidal recess, instrumentation to create or enlarge an ostium into the sphenoid sinus, specimen collection for culture or biopsy if mucosal abnormality or mass is present, and hemostasis. Postoperative workflow includes observation in PACU, nasal saline irrigations, topical steroid considerations, short course antibiotics if indicated, and scheduled follow-up for endoscopic surveillance and pathology review of any biopsy specimens. Documentation should include laterality (if applicable), indication, technique (endoscopic sphenoidotomy), specimens sent, estimated blood loss, and any complications.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    31231Nasal/sinus endoscopy, diagnostic, with endoscope, unilateral or bilateral; with biopsy, polypectomy or debridement (separate procedure)Diagnostic nasal endoscopy and biopsy may be performed before or during sphenoidotomy to evaluate intranasal pathology
    31237Nasal/sinus endoscopy, surgical; with biopsy, excision or ablation (e.g., for polyps), with debridement as necessaryOften performed concurrently when additional sinonasal pathology or polypectomy is required during sphenoid access
    31267Nasal/sinus endoscopy, surgical, with dilation of maxillary ostium, with or without endoscopic assistanceMay be performed in multi-sinus procedures when maxillary disease is present alongside sphenoid disease
    61645Stereotactic computer-assisted (navigational) procedure; intracranial, cranial base or skull baseNavigation assistance is commonly used for sphenoid sinus work near the skull base to increase safety
    60100Biopsy of sinus lesion, external approach (separate procedure)May be used if an external approach or open biopsy is required instead of endoscopic sphenoidotomy

    Related Modifiers

    12 rows

    ModifierDescriptionWhen to Use
    26Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
    50Modifier –50 (Bilateral Procedure) is appended to a CPT code when an identical procedure is performed on paired anatomical structures during the same operative session. The AMA states to add…- Use modifier -50 when the same CPT surgical, diagnostic, or radiology procedure is performed on paired anatomical structures (both sides of the body) during the same operative/session by the same…
    59Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    63Modifier‑63 is appended to surgical CPT codes (20000–69990) when a procedure is performed on a neonate or infant weighing ≤ 4 kg (about 8.8 lbs). The AMA/AAPC definition specifies this use and notes…- Use modifier -63 only for surgical procedures in the CPT 20000–69990 series performed on a neonate or infant who weighs ≤ 4 kg at the time of the procedure; it indicates increased complexity due to…
    76Modifier -76, Repeat Procedure or Service by Same Physician or Other Qualified Health Care Professional, is appended when the same provider performs an identical, medically necessary procedure or…- Use modifier -76 when the same physician or other qualified health care professional performs an identical procedure or service a second (or subsequent) time on the same date of service and the…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…
    79Modifier 79 indicates a surgical procedure performed during the postoperative global period of a prior surgery that is unrelated to the original procedure. Per AMA/CPT and CMS guidance, it is…- Use modifier 79 when the same physician (or same‑specialty physician in the same group) performs a surgical procedure during the postoperative global period of a prior surgery and the new procedure…
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…

    Showing 1–10 of 12

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    207K00000X
    207L00000X
    363L00000X
    246ZE0500X
    3336H0001X
    163WN0300X
    3104A0625X
    261QX0100X

    Related Payer Policy Updates

    Specialty: Otorhinolaryngology (ENT)1 / 2

    10 rows

    PolicyPayerEffective Date
    Office-based Laryngeal ProceduresPremera Bluecross2026-10-06
    Injectable Dermal Fillers and Bulking Agents (for New Mexico Only)UnitedHealthcare2026-10-01
    Injectable Dermal Fillers and Bulking Agents (for Kentucky Only)UnitedHealthcare2026-10-01
    Hearing Aids and Devices Including Wearable, Bone-Anchored, and Semi-Implantable (for Indiana Only)UnitedHealthcare2026-10-01
    Otoacoustic Emissions Testing (for Oxford Only)UnitedHealthcare2026-10-01
    Injectable Dermal Fillers and Bulking AgentsUnitedHealthcare2026-10-01
    Injectable Dermal Fillers and Bulking AgentsUnitedHealthcare2026-10-01
    Sinus Surgeries and Interventions (for North Carolina Only)UnitedHealthcare2026-10-01
    Injectable Dermal Fillers and Bulking Agents (for Nebraska Only)UnitedHealthcare2026-10-01
    Injectable Dermal Fillers and Bulking Agents (for Kansas Only)UnitedHealthcare2026-10-01

    Related Codes

    CPT-31000-MAXILLARY-SINUS-WASHOUT-IRRIGATION

    CPT 31000: Maxillary Sinus Irrigation (Antral Washout)

    CPT-31002-SPHENOID-SINUS-IRRIGATION-FLEXIBLE-CANNULA

    CPT 31002: Sphenoid Sinus Irrigation with Flexible Cannula

    CPT-31020-MIDDLE-MEATAL-SINUSOTOMY-INTRANASAL-SINUSOTOMY

    CPT 31020: Middle Meatal Sinusotomy, Intranasal Approach

    CPT-31030-MAXILLARY-ANTRUM-MUCOSAL-REMOVAL-NASOANTRAL-WINDOW

    CPT 31030: Radical Antral Mucosal Resection with Nasoantral Window

    CPT-31032-MAXILLARY-ANTROSTOMY-POLYPECTOMY

    CPT 31032: Maxillary Antrostomy with Polypectomy

    CPT-31040-PTERYGOMAXILLARY-FOSSA-SURGERY

    CPT 31040: Surgery of the Pterygomaxillary Fossa

    CPT-31051-SPHENOID-SINUS-MUCOSA-STRIPPING-POLYPECTOMY

    CPT 31051: Sphenoid Sinus Incision with Polyp Removal or Mucosal Stripping

    CPT-31070-TREPHINATION-FRONTAL-SINUS-OPENING

    CPT 31070: Frontal Sinus Trephination

    CPT-31075-FRONTAL-SINUS-EXCISION-TRANSORBITAL-APPROACH

    CPT 31075: Frontal Sinus Excision via Orbital Approach

    CPT-31080-FRONTAL-SINUS-OBLITERATION-EXTERNAL-APPROACH

    CPT 31080: Frontal Sinus Obliteration via Sub-brow Incision

    Showing 1–10 of 16

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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