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    v1.0.30
    OpenPayerBilling CodesOther Procedures on the Femur or Knee JointCPT cpt-27599-unlisted-femur-knee-procedure
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    CPT 27599: Unlisted Procedure on Femur or Knee

    Commercial payers pay $1634 on average nationally for this procedure.

    CPT code 27599 is an unlisted procedure code used to report surgical procedures on the femur or knee that do not have a specific CPT code; it represents operative interventions (surgical procedures) and is typically reported for inpatient or outpatient surgical services performed in an operating room or ambulatory surgical center.

    For related coverage guidance, see recent payer policy updates: Implants for Joint Pain, Orthopedic Applications of Stem Cell Therapy, Bone Lengthening (Distraction Osteogenesis).

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    National Reimbursement Benchmarks

    Commercial national rates for CPT 27599 cluster around BUCA’s average commercial benchmark of $1,633.60, with substantial variation among major payers. Blue Cross Blue Shield shows extreme high-end outliers (max $63,000) and a median at $231.50, while Aetna’s central tendency (median $1,136.10) sits near BUCA’s average. Cigna’s median of $680 and UnitedHealth Group’s median of $698 are lower than the BUCA mean, and BUCA’s own median of $491.50 indicates skewed distributions across insurers.

    Dispersion measured as P75 minus P25 highlights which payers are tightest or widest: Aetna’s interquartile range is $2,931.20 − $672.00 = $2,259.20, Blue Cross Blue Shield’s IQR is $302.80 − $216.00 = $86.80 (the tightest), Cigna’s IQR is $1,292.10 − $508.00 = $784.10, UnitedHealth Group’s IQR is $1,535.10 − $252.30 = $1,282.80, and BUCA’s IQR is $995.70 − $328.00 = $667.70. Blue Cross Blue Shield therefore appears the tightest in the middle 50% while Aetna shows the widest middle spread.

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    National Payer Mean Reimbursement Rates

    State Reimbursement Rates

    State: Alaska1 / 51

    Rate by payer

    Clinical & Coding Specifications

    Clinical Context

    A 68-year-old patient presents to the orthopaedic clinic with progressive right knee pain and mechanical symptoms after a recent fall. Imaging demonstrates an atypical femoral or periarticular knee injury that does not match a specific indexed procedure code. The patient has either underlying unilateral primary osteoarthritis of the right knee (M17.11) or an acute femoral neck fracture on initial encounter for closed fracture (S72.001A) depending on presentation. Evaluation includes history, physical exam, radiographs, and possible CT or MRI when fracture pattern or intra-articular pathology is unclear. When nonoperative management is inappropriate, the orthopaedic surgeon schedules an operative intervention using an unlisted femur/knee code 27599 to report a uniquely performed reconstructive, fixation, or combined procedure on the femur or knee that lacks a specific CPT descriptor.

    Preoperative workflow includes informed consent, medical clearance, and baseline labs. Intraoperative steps vary by pathology but can include exposure of the femur or knee, debridement, fixation or reconstruction, and intraoperative imaging. Operative documentation must detail procedural steps, implants used, time, and rationale for use of an unlisted code. Postoperative care includes pain control, DVT prophylaxis, wound checks, mobilization per weight-bearing status, and follow-up imaging. Claims routinely append appropriate modifiers (for example LT/RT, 62, or 59) and include operative report, implant/device documentation, and relevant imaging to support medical necessity for 27599.

    Related CPT Codes

    Related Modifiers

    11 rows

    ModifierDescriptionWhen to Use
    59Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    51Modifier –51 (Multiple Procedures) is used when the same provider performs multiple procedures in the same session to identify secondary, non‑exempt procedures and indicate payment reduction logic…- Use modifier -51 when the same provider performs multiple distinct procedures during the same patient encounter: report the highest‑valued procedure first (no modifier) and append -51 to…
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…
    79Modifier 79 indicates a surgical procedure performed during the postoperative global period of a prior surgery that is unrelated to the original procedure. Per AMA/CPT and CMS guidance, it is…- Use modifier 79 when the same physician (or same‑specialty physician in the same group) performs a surgical procedure during the postoperative global period of a prior surgery and the new procedure…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    74Modifier ‑74 indicates an outpatient hospital or ASC procedure that was discontinued after anesthesia was administered and after the procedure had begun. Use this modifier when anesthesia (local,…- Use modifier -74 when a procedure in an outpatient hospital or ASC setting is terminated after anesthesia has been administered and after the procedure has commenced (for example, after incision,…
    80CPT® Modifier 80 (Assistant Surgeon) is appended to a surgical CPT code when a physician (MD or DO) provides full, continuous assistance throughout the operative procedure. It is intended only for…- Use CPT Modifier -80 when a physician (MD or DO) serves as an assistant surgeon and provides full, continuous assistance throughout the entire operative procedure; append -80 to the surgical CPT…

    Showing 1–10 of 11

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    207X00000X
    207XX0004X
    207XS0117X
    207YP0228X
    282NW0100X
    207WX0120X
    246QL0901X
    261QM1200X

    Related Payer Policy Updates

    Specialty: Orthopedics/Musculoskeletal1 / 2

    10 rows

    PolicyPayerEffective Date
    Implants for Joint PainBlue Cross Blue Shield - Rhode Island2027-03-01
    Orthopedic Applications of Stem Cell TherapyBlue Cross Blue Shield - Rhode Island2027-01-01
    Bone Lengthening (Distraction Osteogenesis)Blue Cross Blue Shield - North Dakota2027-01-01
    Orthopedic Joint Procedures of the Knee for Managed Medicaid (MMC), Health and Recovery Plan (HARP), Child Health Plus (CHP), and Essential Plan (EP) Membersuniverahealthcare2027-01-01
    Sacroiliac Joint Fusion for the Treatment of Adult Low-Back Pain Medical PolicyHealth-New-England2026-12-01
    Bone Grafts and Stabilization Devices for Spinal Defects - Medical PolicyHealth-New-England2026-12-01
    Implantable Shock Absorbers for Treatment of Knee Osteoarthritisblue cross blue shield - louisiana2026-12-01
    Autologous Chondrocyte Transplantation or Implantation Corporate Medical Policybcbsvermont2026-12-01
    Cartilage Implants for Joint Painpremerabluecrossofwashington2026-11-06
    Cartilage Implants for Joint Painpremerabluecrossofwashington2026-11-06

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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    CPT CodeDescriptionRelationship to This Procedure
    27447Total knee arthroplastyDefinitive joint replacement for advanced knee osteoarthritis; an alternate indexed procedure when total knee arthroplasty is performed instead of an unlisted femur/knee procedure
    27506Open treatment of femoral fracture, proximal end, neck, internal fixation or prosthetic replacementIndexed procedure for many proximal femur fractures; used when fracture pattern fits a specific code instead of 27599
    29881Arthroscopy, knee, surgical; with meniscectomy (medial OR lateral, including any meniscal shaving)Arthroscopic knee procedures may be performed separately or in conjunction with open femur/knee surgery; reported separately when applicable
    20610Arthrocentesis, aspiration and/or injection into a major joint or bursaDiagnostic or therapeutic joint aspiration/injection performed preoperatively or intraoperatively; billed separately when performed