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    OpenPayerBilling CodesAmputation Procedures on the Femur (Thigh Region) and Knee JointCPT cpt-27598-lower-leg-disarticulation-preserving-femoral-end
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    CPT 27598: Lower Leg Amputation Separating Tibia/Fibula From Femur

    Medicare pays $652 on average nationally for this procedure.

    CPT code 27598 describes a surgical lower leg amputation in which the tibia and fibula are separated from the femur without cutting the femur, permitting residual limb end-bearing; service type: lower extremity amputation surgery; typical site of service: operating room or surgical suite in an acute care hospital or ambulatory surgical center.

    For related coverage guidance, see recent payer policy updates: Implants for Joint Pain, Orthopedic Applications of Stem Cell Therapy, Bone Lengthening (Distraction Osteogenesis).

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    Clinical & Coding Specifications

    Clinical Context

    A typical patient is an adult with a non-salvageable lower leg after severe trauma (e.g., mangling crush injury, ischemic necrosis, or severe infection) or chronic limb-threatening conditions where limb preservation is not possible. The patient presents with uncontrolled pain, nonviable distal tissue, or prosthetic and functional considerations favoring an above-knee amputation that spares cutting the femur.

    Preoperative workflow includes multidisciplinary evaluation (trauma or vascular surgery, orthopedics, anesthesia, rehabilitation and prosthetics consultation), informed consent discussing weight-bearing and prosthetic outcomes, preoperative imaging as needed, and optimization of comorbidities. In the operating room under general or regional anesthesia, the surgeon performs a knee disarticulation (surgical separation of the tibia and fibula from the femur) preserving the femoral length and soft tissue envelope to allow partial weight bearing on the femoral condyles. Postoperative care includes pain control, wound monitoring, early mobilization, physical therapy, and coordination with prosthetics and home health as indicated.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    27880Revision of amputation stump, thigh or leg; without skeletal revisionMay be performed later if stump complications or need for revision after knee disarticulation.
    28800Application of external fixation system, knee and leg; initial placementMay be used prior to definitive amputation in complex trauma to stabilize limb.
    11042Debridement; subcutaneous tissue, first 20 sq cm or lessPreoperative or staged debridement of infected or necrotic tissue before definitive disarticulation.
    20670Removal of implant; deep (e.g., buried pins, rods)Removal of prior hardware that may complicate amputation.
    99281Emergency department visit, problem-focusedTypical initial ED evaluation code when patient presents with acute limb-threatening injury leading to eventual disarticulation.
    97530Therapeutic activities, direct (one-on-one) patient contactPostoperative rehabilitation therapy commonly provided during recovery and prosthetic training.

    Related Modifiers

    11 rows

    ModifierDescriptionWhen to Use
    50Modifier –50 (Bilateral Procedure) is appended to a CPT code when an identical procedure is performed on paired anatomical structures during the same operative session. The AMA states to add…- Use modifier -50 when the same CPT surgical, diagnostic, or radiology procedure is performed on paired anatomical structures (both sides of the body) during the same operative/session by the same…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    66Modifier 66 (Surgical Team) is used when three or more surgeons act as primary surgeons on a single, highly complex procedure. The AMA defines it for use when a surgical team — often composed of…- Use modifier 66 when three or more surgeons act as primary surgeons working collaboratively as a surgical team on a single, highly complex or difficult procedure (for example organ…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…
    79Modifier 79 indicates a surgical procedure performed during the postoperative global period of a prior surgery that is unrelated to the original procedure. Per AMA/CPT and CMS guidance, it is…- Use modifier 79 when the same physician (or same‑specialty physician in the same group) performs a surgical procedure during the postoperative global period of a prior surgery and the new procedure…
    55Modifier –55 indicates the billing provider furnished only postoperative management for a procedure that has a global surgical period. According to AAPC, this modifier is appended to the same CPT…- Use modifier -55 when billing the same CPT surgical code that has a 10- or 90-day global period and you, as a provider other than the original surgeon, furnished ONLY postoperative management (no…
    23Modifier -23 (Unusual Anesthesia) is used on anesthesia service CPT codes when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia…- Use modifier -23 only on anesthesia CPT codes (00100–01999) when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia because of…

    Showing 1–10 of 11

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    2080P0202X
    208000000X
    207L00000X
    2084P0800X
    225100000X
    347D00000X
    163WH0200X
    246QC2700X

    Related Payer Policy Updates

    Specialty: Orthopedics/Musculoskeletal1 / 2

    10 rows

    PolicyPayerEffective Date
    Implants for Joint PainBlue Cross Blue Shield - Rhode Island2027-03-01
    Orthopedic Applications of Stem Cell TherapyBlue Cross Blue Shield - Rhode Island2027-01-01
    Bone Lengthening (Distraction Osteogenesis)Blue Cross Blue Shield - North Dakota2027-01-01
    Orthopedic Joint Procedures of the Knee for Managed Medicaid (MMC), Health and Recovery Plan (HARP), Child Health Plus (CHP), and Essential Plan (EP) Membersuniverahealthcare2027-01-01
    Sacroiliac Joint Fusion for the Treatment of Adult Low-Back Pain Medical PolicyHealth-New-England2026-12-01
    Bone Grafts and Stabilization Devices for Spinal Defects - Medical PolicyHealth-New-England2026-12-01
    Implantable Shock Absorbers for Treatment of Knee Osteoarthritisblue cross blue shield - louisiana2026-12-01
    Autologous Chondrocyte Transplantation or Implantation Corporate Medical Policybcbsvermont2026-12-01
    Cartilage Implants for Joint Painpremerabluecrossofwashington2026-11-06
    Cartilage Implants for Joint Painpremerabluecrossofwashington2026-11-06

    Related Codes

    CPT-27590-FEMORAL-AMPUTATION-ABOVE-KNEE

    CPT 27590: Amputation of Leg Through Femur

    CPT-27591-TRANSFEMORAL-AMPUTATION-IMMEDIATE-PROSTHESIS

    CPT 27591: Transfemoral Amputation with Immediate Prosthesis

    CPT-27592-FEMORAL-TRANSSECTION-FOR-INFECTION-CONTROL

    CPT 27592: Complete Femoral Amputation (Through Femur)

    CPT-27594-HIGH-FEMORAL-AMPUTATION-SECONDARY-CLOSURE

    CPT 27594: Transfemoral (Above-Knee) Amputation with Secondary Closure

    CPT-27596-FEMORAL-STUMP-SHORTENING-AMPUTATION-REVISION

    CPT 27596: Femoral Amputation Residual Limb Shortening

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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