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    OpenPayerBilling CodesAmputation Procedures on the Femur (Thigh Region) and Knee JointCPT cpt-27590-femoral-amputation-above-knee
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    CPT 27590: Amputation of Leg Through Femur

    Medicare pays $726 on average nationally for this procedure.

    CPT code 27590 describes a complete surgical amputation of the leg at any level on the femur (thigh) with closure of remaining muscle and skin layers; this is a major surgical amputation procedure typically performed in an operating room as an inpatient or outpatient surgical service depending on clinical context and perioperative needs.

    For related coverage guidance, see recent payer policy updates: Implants for Joint Pain, Orthopedic Applications of Stem Cell Therapy, Bone Lengthening (Distraction Osteogenesis).

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    Clinical & Coding Specifications

    Clinical Context

    A typical patient is an adult with a nonviable, severely damaged, or infected lower extremity requiring removal at the level of the femur (transfemoral amputation). The clinical workflow begins with preoperative evaluation by an orthopedic or vascular surgeon, including history, vascular studies, infection control, optimization of comorbidities (for example diabetes mellitus and peripheral arterial disease), and informed consent. On the day of surgery the patient is admitted to an operating room or surgical suite; regional or general anesthesia is administered; the surgeon performs a complete amputation of the leg through the femur, achieves hemostasis, contours remaining muscle and soft tissue to form a functional residual limb, and closes the wound in layers. Postoperative care includes pain control, wound and stump care, physical therapy and prosthetic consultation, and coordination of home health or inpatient rehabilitation as needed. Typical site of service is an inpatient hospital operating room or ambulatory surgical center depending on patient acuity and comorbidities. Common clinical indications include critical limb ischemia with gangrene, severe traumatic injury to the femur/leg, uncontrolled osteomyelitis, or malignant tumors involving the lower limb.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    11042Debridement, subcutaneous tissue (eg, fat, muscle)Preoperative debridement for infected soft tissue or chronic wound that may precede amputation.
    27690Other amputation, below knee; including closurePerformed when transtibial amputation is indicated instead of transfemoral; alternative level of amputation.
    69715Repair of amputation stump or revision (example code for stump revision)Used for subsequent stump revision or debridement after initial transfemoral amputation.
    51702Repair of urinary fistula or suprapubic catheter placement (example code for urinary management in complex cases)May be billed when perioperative urinary management procedures are required in complex inpatients.
    99499Unlisted evaluation and management serviceOccasionally used for unique perioperative management services not described by other codes.

    Note: If exact related CPT codes were not provided in the input, these codes reflect commonly associated procedures performed before, during, or after a transfemoral amputation and describe typical workflow relationships.

    Related Modifiers

    13 rows

    ModifierDescriptionWhen to Use
    50Modifier –50 (Bilateral Procedure) is appended to a CPT code when an identical procedure is performed on paired anatomical structures during the same operative session. The AMA states to add…- Use modifier -50 when the same CPT surgical, diagnostic, or radiology procedure is performed on paired anatomical structures (both sides of the body) during the same operative/session by the same…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    54Modifier ‑54 (“Surgical care only”) is appended to a CPT surgical procedure when the reporting surgeon performs the intraoperative (surgical) component but does not furnish the preoperative and/or…- Use modifier -54 when the reporting surgeon provided only the intraoperative (surgical) component of a procedure and preoperative and/or postoperative management has been or will be provided by…
    55Modifier –55 indicates the billing provider furnished only postoperative management for a procedure that has a global surgical period. According to AAPC, this modifier is appended to the same CPT…- Use modifier -55 when billing the same CPT surgical code that has a 10- or 90-day global period and you, as a provider other than the original surgeon, furnished ONLY postoperative management (no…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    63Modifier‑63 is appended to surgical CPT codes (20000–69990) when a procedure is performed on a neonate or infant weighing ≤ 4 kg (about 8.8 lbs). The AMA/AAPC definition specifies this use and notes…- Use modifier -63 only for surgical procedures in the CPT 20000–69990 series performed on a neonate or infant who weighs ≤ 4 kg at the time of the procedure; it indicates increased complexity due to…
    76Modifier -76, Repeat Procedure or Service by Same Physician or Other Qualified Health Care Professional, is appended when the same provider performs an identical, medically necessary procedure or…- Use modifier -76 when the same physician or other qualified health care professional performs an identical procedure or service a second (or subsequent) time on the same date of service and the…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…
    79Modifier 79 indicates a surgical procedure performed during the postoperative global period of a prior surgery that is unrelated to the original procedure. Per AMA/CPT and CMS guidance, it is…- Use modifier 79 when the same physician (or same‑specialty physician in the same group) performs a surgical procedure during the postoperative global period of a prior surgery and the new procedure…

    Showing 1–10 of 13

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    207K00000X
    208000000X
    208200000X
    385HR2055X
    225X00000X
    163WG0100X
    111N00000X
    133VN1301X

    Related Payer Policy Updates

    Specialty: Orthopedics/Musculoskeletal1 / 2

    10 rows

    PolicyPayerEffective Date
    Implants for Joint PainBlue Cross Blue Shield - Rhode Island2027-03-01
    Orthopedic Applications of Stem Cell TherapyBlue Cross Blue Shield - Rhode Island2027-01-01
    Bone Lengthening (Distraction Osteogenesis)Blue Cross Blue Shield - North Dakota2027-01-01
    Orthopedic Joint Procedures of the Knee for Managed Medicaid (MMC), Health and Recovery Plan (HARP), Child Health Plus (CHP), and Essential Plan (EP) Membersuniverahealthcare2027-01-01
    Sacroiliac Joint Fusion for the Treatment of Adult Low-Back Pain Medical PolicyHealth-New-England2026-12-01
    Bone Grafts and Stabilization Devices for Spinal Defects - Medical PolicyHealth-New-England2026-12-01
    Implantable Shock Absorbers for Treatment of Knee Osteoarthritisblue cross blue shield - louisiana2026-12-01
    Autologous Chondrocyte Transplantation or Implantation Corporate Medical Policybcbsvermont2026-12-01
    Cartilage Implants for Joint Painpremerabluecrossofwashington2026-11-06
    Cartilage Implants for Joint Painpremerabluecrossofwashington2026-11-06

    Related Codes

    CPT-27591-TRANSFEMORAL-AMPUTATION-IMMEDIATE-PROSTHESIS

    CPT 27591: Transfemoral Amputation with Immediate Prosthesis

    CPT-27592-FEMORAL-TRANSSECTION-FOR-INFECTION-CONTROL

    CPT 27592: Complete Femoral Amputation (Through Femur)

    CPT-27594-HIGH-FEMORAL-AMPUTATION-SECONDARY-CLOSURE

    CPT 27594: Transfemoral (Above-Knee) Amputation with Secondary Closure

    CPT-27596-FEMORAL-STUMP-SHORTENING-AMPUTATION-REVISION

    CPT 27596: Femoral Amputation Residual Limb Shortening

    CPT-27598-LOWER-LEG-DISARTICULATION-PRESERVING-FEMORAL-END

    CPT 27598: Lower Leg Amputation Separating Tibia/Fibula From Femur

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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