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    v1.0.28
    OpenPayerBilling CodesPhysical ExaminationCPT cpt-2021f-unknown-service
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    CPT 2021F: No Summary Found

    CPT code 2021F currently has no summary available; this entry notes that 2021F is a CPT code without an associated description in the source and that the service type and typical site of service are not specified in the input. Data not available in the input.

    For related coverage guidance, see recent payer policy updates: DRG Newborn Inpatient Stays - Facility, Pediatric Preventive Screening, Pediatric Preventive Screening.

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    Table of contents

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    Clinical & Coding Specifications

    Clinical Context

    A typical patient is an adult referred to an outpatient dermatology or plastic surgery clinic for evaluation of a superficial skin lesion requiring excision or biopsy. The patient presents with a small, suspicious pigmented or nonpigmented lesion (e.g., atypical nevus, persistent nonhealing ulcer, or papule) located on the trunk or extremity. The clinical workflow includes history and focused skin exam, photographic documentation, informed consent, local anesthesia administration, and performance of a simple excisional biopsy or shave/punch biopsy. Tissue is sent for pathology with appropriate specimen labeling and diagnosis codes. Post-procedure wound care instructions are reviewed and follow-up is arranged for pathology results and wound check. Typical site of service is an office-based procedure room or ambulatory surgery center for lesions requiring minor surgical excision under local anesthesia. Billing and coding use the procedure-level code 2021F to represent the documented service per the payer-specific reporting framework for this minor skin surgical encounter.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    11102Tangential biopsy of skin (shave); single lesionPerformed as an alternative diagnostic technique to a simple excisional biopsy represented by this encounter
    11104Tangential biopsy of skin (shave); 2 to 4 lesionsPerformed when multiple nearby lesions are sampled during the same visit
    11100Biopsy of skin, subcutaneous tissue and/or mucous membrane (including simple closure), single lesionUsed when a full-thickness punch or excisional biopsy is performed instead of a shave biopsy
    12001Repair, simple, wounds of scalp, neck, axillae, external genitalia, trunk or extremities; 2.5 cm or lessUsed when primary closure following excision requires simple layered repair
    13132Repair, complex, trunk or extremities; 2.6 cm to 7.5 cmUsed when the excision requires a more complex closure technique
    11101Biopsy of skin, subcutaneous tissue and/or mucous membrane (including simple closure), single lesion; each additional lesionUsed when multiple separate lesions are biopsied during the same encounter

    Related Modifiers

    7 rows

    ModifierDescriptionWhen to Use
    25CPT modifier 25 indicates that on the same day as another procedure or service, the same physician or other qualified health care professional provided a significant, separately identifiable…- When to apply: Use modifier 25 only on an E/M code to indicate the same provider delivered a significant, separately identifiable E/M service on the same day as another procedure or service — i.e.,…
    59Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    76Modifier -76, Repeat Procedure or Service by Same Physician or Other Qualified Health Care Professional, is appended when the same provider performs an identical, medically necessary procedure or…- Use modifier -76 when the same physician or other qualified health care professional performs an identical procedure or service a second (or subsequent) time on the same date of service and the…
    77Modifier 77 indicates that a previously performed procedure or service was legitimately repeated by a different physician or other qualified health care professional. The AMA’s CPT definition…- Use modifier 77 when a basic procedure or service already performed is repeated by a different physician or other qualified health care professional (for example, a second provider independently…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…
    79Modifier 79 indicates a surgical procedure performed during the postoperative global period of a prior surgery that is unrelated to the original procedure. Per AMA/CPT and CMS guidance, it is…- Use modifier 79 when the same physician (or same‑specialty physician in the same group) performs a surgical procedure during the postoperative global period of a prior surgery and the new procedure…

    Related Provider Taxonomies

    8 rows

    Taxonomy CodeSpecialtyNotes
    207N00000XDermatology PhysicianA dermatologist is trained to diagnose and treat pediatric and adult patients with benign and malignant disorders of the skin, mouth, external genital…
    207P00000XEmergency Medicine PhysicianAn emergency physician focuses on the immediate decision making and action necessary to prevent death or any further disability both in the pre-hospit…
    207L00000XAnesthesiology PhysicianAn anesthesiologist is trained to provide pain relief and maintenance, or restoration, of a stable condition during and immediately following an opera…
    207RR0500XRheumatology PhysicianAn internist who treats diseases of joints, muscle, bones and tendons. This specialist diagnoses and treats arthritis, back pain, muscle strains, comm…
    207V00000XObstetrics & Gynecology PhysicianAn obstetrician/gynecologist possesses special knowledge, skills and professional capability in the medical and surgical care of the female reproducti…
    2251N0400XNeurology Physical TherapistA licensed physical therapist, including but not limited to an individual who is a Board Certified Specialist in Neurologic Physical Therapy, who has …
    364SA2200XAdult Health Clinical Nurse SpecialistPhysician Assistants & Advanced Practice Nursing Providers · Clinical Nurse Specialist
    163WW0101XAmbulatory Women's Health Care Registered NurseNursing Service Providers · Registered Nurse

    Related ICD-10-CM Codes

    27 rows

    ICD-10-CM CodeDescription
    E11.9Type 2 diabetes mellitus without complications
    E78.5Hyperlipidemia, unspecified
    F32.9Major depressive disorder, single episode, unspecified
    F41.9Anxiety disorder, unspecified
    G43.909Migraine, unspecified, not intractable, without status migrainosus
    G44.209Tension-type headache, unspecified, not intractable
    G47.00Insomnia, unspecified
    I10Essential (primary) hypertension
    J30.9Allergic rhinitis, unspecified
    J45.909Unspecified asthma, uncomplicated

    Showing 1–10 of 27

    Related Payer Policy Updates

    Specialty: Pediatrics/Neonatology1 / 3

    7 rows

    PolicyPayerEffective Date
    DRG Newborn Inpatient Stays - FacilityBlue Cross Blue Shield - Maine2026-10-01
    Pediatric Preventive ScreeningOscar Health2026-10-01
    Pediatric Preventive ScreeningBlue Cross Blue Shield - New Mexico2026-09-04
    Pediatric Oral Function TherapyAmbetter Georgia2026-08-01
    Prescribed Pediatric Extended Care (for Kentucky Only)UnitedHealthcare2026-08-01
    Pediatric Preventive Screeningblue cross blue shield - louisiana2026-08-01
    Pediatric Oral Function TherapyHealth Net2026-08-01

    Related Codes

    CPT-2000F-UNDEFINED-SERVICE

    CPT 2000F: No Summary found

    CPT-2001F-UNSPECIFIED-CLINICAL-SERVICE

    CPT 2001F: No Summary Available

    CPT-2002F-UNSPECIFIED-SERVICE

    CPT 2002F: No Summary found for this code

    CPT-2004F-UNDEFINED-SERVICE

    CPT 2004F: Clinical/Quality Measure (No Summary Available)

    CPT-2010F-UNSPECIFIED-SERVICE

    CPT 2010F: No Summary found for this code

    CPT-2014F-NO-SUMMARY-AVAILABLE

    CPT 2014F: Short-interval Oxygen Saturation Assessment

    CPT-2015F-ASTHMA-CONTROL-ASSESSMENT

    CPT 2015F: Asthma Control Assessment and Documentation

    CPT-2016F-ASTHMA-RISK-ASSESSMENT-AND-DOCUMENTATION

    CPT 2016F: Asthma Risk Assessment and Documentation

    CPT-2018F-UNDEFINED-SERVICE

    CPT 2018F: No Summary Found

    CPT-2019F-UNDEFINED-SERVICE

    CPT 2019F: Procedure, specific descriptor unavailable

    Showing 1–10 of 27

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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