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    v1.0.28
    OpenPayerBilling CodesMalignant neoplasms of bone and articular cartilageICD-10-CM c41-malignant-neoplasm-of-bone
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    ICD-10-CM Code For Malignant Neoplasm Of Bone And Articular Cartilage Of Other And Unspecified Sites: Group Overview

    The International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) code group C41 includes malignant neoplasms of bone and articular cartilage at other and unspecified sites, covering tumors of long bones, pelvic bones, vertebral column, and bones at unspecified locations. These ICD-10-CM diagnosis codes are used to document primary malignant bone tumors, capture site-specific involvement, and reflect histologic and anatomical detail relevant to staging and treatment planning. Accurate coding within the ICD-10-CM C41 group supports proper claim adjudication, complete clinical documentation, and appropriate reimbursement.

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    ICD-10-CM C41: Malignant Neoplasm Of Bone And Articular Cartilage Of Other And Unspecified Sites Overview

    This group represents malignant tumors originating in bone and articular cartilage at less common or unspecified anatomical sites, including long bones, pelvic bones, vertebral column, and unspecified locations. These conditions target the skeletal system and periarticular structures and often require precise anatomical and histological documentation. Accurate coding matters for reimbursement because it links clinical documentation to the appropriate diagnosis codes that support claim adjudication and severity-based payment.

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    When to Use

    Use a code from this group when a documented primary malignant tumor of bone or articular cartilage is identified and the clinician provides the specific anatomic site or indicates an unspecified bone site. Select the most specific code available that matches the documented location and laterality to reflect clinical complexity and support accurate billing.

    ICD-10-CM Codes

    6 rows

    ICD-10-CM CodeDescription
    C41.0Malignant neoplasm of bones of skull and face
    C41.1Malignant neoplasm of mandible
    C41.2Malignant neoplasm of vertebral column
    C41.3Malignant neoplasm of ribs, sternum and clavicle
    C41.4Malignant neoplasm of pelvic bones, sacrum and coccyx
    C41.9Malignant neoplasm of bone and articular cartilage, unspecified

    DRG Codes

    9 rows

    DRG CodeDescription
    011Tracheostomy for Face, Mouth and Neck Diagnoses or Laryngectomy with MCC
    012Tracheostomy for Face, Mouth and Neck Diagnoses or Laryngectomy with CC
    013Tracheostomy for Face, Mouth and Neck Diagnoses or Laryngectomy without CC/MCC
    456Spinal Fusion Except Cervical with Spinal Curvature, Malignancy, Infection or Extensive Fusions with MCC
    457Spinal Fusion Except Cervical with Spinal Curvature, Malignancy, Infection or Extensive Fusions with CC
    458Spinal Fusion Except Cervical with Spinal Curvature, Malignancy, Infection or Extensive Fusions without CC/MCC
    542Pathological Fractures and Musculoskeletal and Connective Tissue Malignancy with MCC
    543Pathological Fractures and Musculoskeletal and Connective Tissue Malignancy with CC
    544Pathological Fractures and Musculoskeletal and Connective Tissue Malignancy without CC/MCC

    Typical Clinical Scenarios

    • An elderly patient presents to the orthopedic clinic with progressive localized bone pain and a palpable mass over the proximal femur causing functional limitation over months. Imaging (X‑ray and MRI) shows a destructive lytic lesion of the femoral neck with cortical breakthrough, and biopsy confirms a primary malignant bone tumor of the femur; a code from this group is assigned to document the malignant neoplasm at the femoral site. Typical codes: C41.2
    • A middle‑aged adult arrives to the emergency department with acute severe back pain, new lower extremity weakness, and sensory changes after weeks of worsening thoracic pain; spinal imaging reveals a pathologic compression fracture from a malignant bone lesion in the thoracic vertebra. Because the presentation is an acute complication of a primary malignant bone tumor located in the vertebral column, a site‑specific code from this group is used. Typical codes: C41.4
    • A young adult with a known malignant bone tumor of the pelvic bones undergoing oncology follow‑up for staging and treatment planning after neoadjuvant therapy presents for surveillance imaging; persistent irregular pelvic bone lesion consistent with residual or recurrent disease is documented and coded to reflect the malignant neoplasm of the pelvis. Typical codes: C41.3, C41.9

    Related Codes

    C40-MALIGNANT-NEOPLASM-OF-LIMBS

    ICD-10-CM Code For Malignant Neoplasm Of Bone And Articular Cartilage Of Limbs: Group Overview

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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