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    v1.0.28
    OpenPayerBilling CodesHelminthiasesICD-10-CM b66-other-fluke-infections
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    ICD-10-CM Code For Other Fluke Infections: Group Overview

    The International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) code group B66 includes infections caused by flukes (trematodes), such as hepatic and intestinal fluke infections, and other less common trematodiases affecting various organ systems. These ICD-10-CM diagnosis codes are used to document clinical presentations ranging from asymptomatic infection to symptomatic organ-specific disease, capturing disease severity, organ involvement, or clinical complexity relevant to this group. Accurate coding within the ICD-10-CM B66 group supports proper claim adjudication, complete clinical documentation, and appropriate reimbursement.

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    ICD-10-CM B66: Other Fluke Infections Overview

    The ICD-10-CM B66 group covers infections caused by trematode parasites (flukes) affecting various organs, most commonly the liver and biliary system. These diagnoses represent helminthic infections that can cause cholangitis, biliary obstruction, or hepatic inflammation. Accurate coding matters for appropriate clinical documentation and reimbursement because it reflects organ involvement and treatment intensity.

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    When to Use

    Use a code from this group when a clinical diagnosis or confirmed laboratory identification indicates infection with a trematode (fluke) species. Select the code that reflects the specific type of fluke infection and any documented organ involvement or complications.

    ICD-10-CM Codes

    8 rows

    ICD-10-CM CodeDescription
    B66.0Opisthorchiasis
    B66.1Clonorchiasis
    B66.2Dicroceliasis
    B66.3Fascioliasis
    B66.4Paragonimiasis
    B66.5Fasciolopsiasis
    B66.8Other specified fluke infections
    B66.9Fluke infection, unspecified

    DRG Codes

    9 rows

    DRG CodeDescription
    177Respiratory Infections and Inflammations with MCC
    178Respiratory Infections and Inflammations with CC
    179Respiratory Infections and Inflammations without CC/MCC
    441Disorders of Liver Except Malignancy, Cirrhosis or Alcoholic Hepatitis with MCC
    442Disorders of Liver Except Malignancy, Cirrhosis or Alcoholic Hepatitis with CC
    443Disorders of Liver Except Malignancy, Cirrhosis or Alcoholic Hepatitis without CC/MCC
    867Other Infectious and Parasitic Diseases Diagnoses with MCC
    868Other Infectious and Parasitic Diseases Diagnoses with CC
    869Other Infectious and Parasitic Diseases Diagnoses without CC/MCC

    Typical Clinical Scenarios

    • An adult patient presents to urgent care with several days of fever, right upper quadrant abdominal pain, hepatomegaly on exam, and new eosinophilia after returning from freshwater snail–endemic areas. Imaging shows hepatic abscesses and serology is positive for Fasciola infection; the clinician documents an active fluke infection causing hepatic involvement, so a specific code from this group is assigned. Typical codes: B66.0, B66.1
    • A school-aged child from a rural community is evaluated in primary care for chronic intermittent abdominal pain, anemia, and failure to thrive; stool ova and parasite testing identifies intestinal trematode eggs consistent with infection by an intestinal fluke species. Because this is an ongoing parasitic infection affecting growth and nutrition, an appropriate code from the group is used for the chronic helminthic infection. Typical codes: B66.2, B66.3
    • An older patient with recurrent biliary colic and cholangitis is admitted; endoscopic retrograde cholangiopancreatography retrieves adult flukes from the common bile duct and cultures show secondary bacterial infection. The hospitalization documents the fluke infection as a complicating/morbid condition contributing to the acute cholangitis, so one of the fluke infection codes is assigned alongside codes for biliary infection. Typical codes: B66.4, B66.8

    Related Codes

    B65-SCHISTOSOMIASIS-BILHARZIASIS

    ICD-10-CM Code For Schistosomiasis Bilharziasis: Group Overview

    B67-ECHINOCOCCOSIS

    ICD-10-CM Code For Echinococcosis: Group Overview

    B68-TAENIASIS

    ICD-10-CM Code For Taeniasis: Group Overview

    B69-CYSTICERCOSIS

    ICD-10-CM Code For Cysticercosis: Group Overview

    B70-DIPHYLLOBOTHRIASIS-AND-SPARGANOSIS

    ICD-10-CM Code For Diphyllobothriasis And Sparganosis: Group Overview

    B71-OTHER-CESTODE-INFECTIONS

    ICD-10-CM Code For Other Cestode Infections: Group Overview

    B72-DRACUNCULIASIS

    ICD-10-CM Code For Dracunculiasis: Group Overview

    B73-ONCHOCERCIASIS

    ICD-10-CM Code For Onchocerciasis: Group Overview

    B74-FILARIASIS-AND-FILARIAL-INFECTIONS

    ICD-10-CM Code For Filariasis: Group Overview

    B75-TRICHINELLOSIS

    ICD-10-CM Code For Trichinellosis: Group Overview

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    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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