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    OpenPayerBilling CodesCertain zoonotic bacterial diseasesICD-10-CM a25-rat-bite-fevers
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    ICD-10-CM Code For Rat Bite Fevers: Group Overview

    The International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) code group A25 includes rat-bite fevers and related infections transmitted from rodents, covering Streptobacillus moniliformis and Spirillum minus infections and their systemic presentations. These ICD-10-CM diagnosis codes are used to document clinical scenarios such as febrile systemic illness after rodent exposure, infections with rash or arthralgia, and complications requiring specific antimicrobial therapy. Accurate coding within the ICD-10-CM A25 group supports proper claim adjudication and ensures complete clinical documentation and appropriate reimbursement.

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    ICD-10-CM A25: Rat-bite Fevers Overview

    The ICD-10-CM A25 group represents infections caused by bacteria transmitted from rodents to humans, including rat-bite fever due to Streptobacillus moniliformis and Spirillum minus. These diagnoses affect the infectious disease system and can involve systemic illness with fever, rash, and joint symptoms. Accurate coding matters for correct claim adjudication and reflects the clinical complexity and treatment needs.

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    When to Use

    Use a code from this group when a patient presents with a documented rodent-related bacterial infection consistent with rat-bite fever or when laboratory identification confirms Streptobacillus moniliformis or Spirillum minus. Codes from this group are also appropriate when clinical documentation describes systemic symptoms such as fever, rash, or arthritis following rodent exposure.

    ICD-10-CM Codes

    3 rows

    ICD-10-CM CodeDescription
    A25.0Spirillosis
    A25.1Streptobacillosis
    A25.9Rat-bite fever, unspecified

    DRG Codes

    3 rows

    DRG CodeDescription
    867Other Infectious and Parasitic Diseases Diagnoses with MCC
    868Other Infectious and Parasitic Diseases Diagnoses with CC
    869Other Infectious and Parasitic Diseases Diagnoses without CC/MCC

    Typical Clinical Scenarios

    • An adult presents to the emergency department with acute high fever, rigors, diffuse myalgias, headache, and a history of a recent rat bite on the hand that became erythematous and tender. The patient is febrile and hypotensive, and blood cultures are pending; the clinical picture and exposure history prompt an initial diagnosis from this group for acute rat-bite–associated systemic infection. Typical codes: A25.0, A25.9
    • A pediatric patient is brought to urgent care several days after a rodent exposure with persistent fever, localized swollen lymph nodes near a bite site, and a skin lesion showing purulent drainage; outpatient management is initiated for a localized rat-bite infection without systemic signs. Because the encounter documents a localized wound infection following a rat bite, a specific code indicating rat-bite fever with pharyngitis or localized soft tissue infection is assigned from the group. Typical codes: A25.0, A25.1
    • An elderly nursing home resident with multiple comorbidities develops unexplained fever, arthritis of multiple joints, and endocarditis suspected after recent exposure to rodents in the facility; rat-bite fever is considered as a complicating zoonotic cause contributing to the infectious process and comorbidity profile. A code from the group is used to capture the complicating zoonotic bacterial disease in the patient’s problem list and claims. Typical codes: A25.1, A25.9

    Related Codes

    A20-PLAGUE

    ICD-10-CM Code For Plague: Group Overview

    A21-TULAREMIA

    ICD-10-CM Code For Tularemia: Group Overview

    A22-ANTHRAX

    ICD-10-CM Code For Anthrax: Group Overview

    A23-BRUCELLOSIS

    ICD-10-CM Code For Brucellosis: Group Overview

    A24-GLANDERS-AND-MELIOIDOSIS

    ICD-10-CM Code For Glanders And Melioidosis: Group Overview

    A26-ERYSIPELOID-INFECTION

    ICD-10-CM Code For Erysipeloid: Group Overview

    A27-LEPTOSPIROSIS

    ICD-10-CM Code For Leptospirosis: Group Overview

    A28-OTHER-ZOONOTIC-BACTERIAL-DISEASES

    ICD-10-CM Code For Other Zoonotic Bacterial Diseases Not Elsewhere Classified: Group Overview

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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