ICD-10-CM Code For Rat Bite Fevers: Group Overview

The International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) code group A25 includes rat-bite fevers and related infections transmitted from rodents, covering Streptobacillus moniliformis and Spirillum minus infections and their systemic presentations. These ICD-10-CM diagnosis codes are used to document clinical scenarios such as febrile systemic illness after rodent exposure, infections with rash or arthralgia, and complications requiring specific antimicrobial therapy. Accurate coding within the ICD-10-CM A25 group supports proper claim adjudication and ensures complete clinical documentation and appropriate reimbursement.

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ICD-10-CM A25: Rat-bite Fevers Overview

The ICD-10-CM A25 group represents infections caused by bacteria transmitted from rodents to humans, including rat-bite fever due to Streptobacillus moniliformis and Spirillum minus. These diagnoses affect the infectious disease system and can involve systemic illness with fever, rash, and joint symptoms. Accurate coding matters for correct claim adjudication and reflects the clinical complexity and treatment needs.

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ICD-10-CM Code For Rat Bite Fevers: Group Overview

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ICD-10-CM A25: Rat-bite Fevers Overview

When to Use

Use a code from this group when a patient presents with a documented rodent-related bacterial infection consistent with rat-bite fever or when laboratory identification confirms Streptobacillus moniliformis or Spirillum minus. Codes from this group are also appropriate when clinical documentation describes systemic symptoms such as fever, rash, or arthritis following rodent exposure.

ICD-10-CM Codes

3 rows

ICD-10-CM Code	Description
A25.0	Spirillosis
A25.1	Streptobacillosis
A25.9	Rat-bite fever, unspecified

DRG Codes

3 rows

DRG Code	Description
867	Other Infectious and Parasitic Diseases Diagnoses with MCC
868	Other Infectious and Parasitic Diseases Diagnoses with CC
869	Other Infectious and Parasitic Diseases Diagnoses without CC/MCC

Typical Clinical Scenarios

An adult presents to the emergency department with acute high fever, rigors, diffuse myalgias, headache, and a history of a recent rat bite on the hand that became erythematous and tender. The patient is febrile and hypotensive, and blood cultures are pending; the clinical picture and exposure history prompt an initial diagnosis from this group for acute rat-bite–associated systemic infection. Typical codes: A25.0, A25.9
A pediatric patient is brought to urgent care several days after a rodent exposure with persistent fever, localized swollen lymph nodes near a bite site, and a skin lesion showing purulent drainage; outpatient management is initiated for a localized rat-bite infection without systemic signs. Because the encounter documents a localized wound infection following a rat bite, a specific code indicating rat-bite fever with pharyngitis or localized soft tissue infection is assigned from the group. Typical codes: A25.0, A25.1
An elderly nursing home resident with multiple comorbidities develops unexplained fever, arthritis of multiple joints, and endocarditis suspected after recent exposure to rodents in the facility; rat-bite fever is considered as a complicating zoonotic cause contributing to the infectious process and comorbidity profile. A code from the group is used to capture the complicating zoonotic bacterial disease in the patient’s problem list and claims. Typical codes: A25.1, A25.9

Related Codes

A20-PLAGUE

ICD-10-CM Code For Plague: Group Overview

A21-TULAREMIA

ICD-10-CM Code For Tularemia: Group Overview

A22-ANTHRAX

ICD-10-CM Code For Anthrax: Group Overview

A23-BRUCELLOSIS

ICD-10-CM Code For Brucellosis: Group Overview

A24-GLANDERS-AND-MELIOIDOSIS

ICD-10-CM Code For Glanders And Melioidosis: Group Overview

A26-ERYSIPELOID-INFECTION

ICD-10-CM Code For Erysipeloid: Group Overview

A27-LEPTOSPIROSIS

ICD-10-CM Code For Leptospirosis: Group Overview

A28-OTHER-ZOONOTIC-BACTERIAL-DISEASES

ICD-10-CM Code For Other Zoonotic Bacterial Diseases Not Elsewhere Classified: Group Overview

Frequently Asked Questions

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

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When to Use

ICD-10-CM Codes

3 rows

ICD-10-CM Code	Description
A25.0	Spirillosis
A25.1	Streptobacillosis
A25.9	Rat-bite fever, unspecified

DRG Codes

3 rows

DRG Code	Description
867	Other Infectious and Parasitic Diseases Diagnoses with MCC
868	Other Infectious and Parasitic Diseases Diagnoses with CC
869	Other Infectious and Parasitic Diseases Diagnoses without CC/MCC

Typical Clinical Scenarios

An adult presents to the emergency department with acute high fever, rigors, diffuse myalgias, headache, and a history of a recent rat bite on the hand that became erythematous and tender. The patient is febrile and hypotensive, and blood cultures are pending; the clinical picture and exposure history prompt an initial diagnosis from this group for acute rat-bite–associated systemic infection. Typical codes: A25.0, A25.9
A pediatric patient is brought to urgent care several days after a rodent exposure with persistent fever, localized swollen lymph nodes near a bite site, and a skin lesion showing purulent drainage; outpatient management is initiated for a localized rat-bite infection without systemic signs. Because the encounter documents a localized wound infection following a rat bite, a specific code indicating rat-bite fever with pharyngitis or localized soft tissue infection is assigned from the group. Typical codes: A25.0, A25.1
An elderly nursing home resident with multiple comorbidities develops unexplained fever, arthritis of multiple joints, and endocarditis suspected after recent exposure to rodents in the facility; rat-bite fever is considered as a complicating zoonotic cause contributing to the infectious process and comorbidity profile. A code from the group is used to capture the complicating zoonotic bacterial disease in the patient’s problem list and claims. Typical codes: A25.1, A25.9

Related Codes

A20-PLAGUE

ICD-10-CM Code For Plague: Group Overview

A21-TULAREMIA

ICD-10-CM Code For Tularemia: Group Overview

A22-ANTHRAX

ICD-10-CM Code For Anthrax: Group Overview

A23-BRUCELLOSIS

ICD-10-CM Code For Brucellosis: Group Overview

A24-GLANDERS-AND-MELIOIDOSIS

ICD-10-CM Code For Glanders And Melioidosis: Group Overview

A26-ERYSIPELOID-INFECTION

ICD-10-CM Code For Erysipeloid: Group Overview

A27-LEPTOSPIROSIS

ICD-10-CM Code For Leptospirosis: Group Overview

A28-OTHER-ZOONOTIC-BACTERIAL-DISEASES

ICD-10-CM Code For Other Zoonotic Bacterial Diseases Not Elsewhere Classified: Group Overview

Frequently Asked Questions

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

Published by

Trek Health powers OpenPayer with a leading commercial payer intelligence platform, seamlessly converting fragmented payer data into actionable insights for provider organizations.

ICD-10-CM Code For Rat Bite Fevers: Group Overview

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ICD-10-CM A25: Rat-bite Fevers Overview

ICD-10-CM Code For Rat Bite Fevers: Group Overview

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ICD-10-CM A25: Rat-bite Fevers Overview

When to Use

ICD-10-CM Codes

DRG Codes

Typical Clinical Scenarios

Related Codes

Which diagnoses are included in the ICD-10-CM A25 group?

When should a coder assign `A25.1` versus `A25.0`?

How does accurate coding within the A25 group affect reimbursement?

What clinical presentations are captured by the A25 codes?

Which DRGs are related to the A25 diagnosis group for inpatient billing?

References

When to Use

ICD-10-CM Codes

DRG Codes

Typical Clinical Scenarios

Related Codes

Which diagnoses are included in the ICD-10-CM A25 group?

When should a coder assign `A25.1` versus `A25.0`?

How does accurate coding within the A25 group affect reimbursement?

What clinical presentations are captured by the A25 codes?

Which DRGs are related to the A25 diagnosis group for inpatient billing?

References