ICD-10-PCS Code For Pituitary Gland: Procedure Code Group Overview

The International Classification of Diseases, Tenth Revision, Procedure Coding System (ICD-10-PCS) code group 0G50 includes procedures performed to destroy tissue of the pituitary gland in the endocrine system. These ICD-10-PCS codes are used for inpatient documentation when pituitary tissue is intentionally eradicated using energy, force, or destructive agents to treat or manage disease. Accurate coding within the ICD-10-PCS 0G50 group is essential for proper inpatient reimbursement, as it captures the procedure performed and supports clinical documentation accuracy.

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Pituitary Gland Destruction Procedure Overview

Procedures in this ICD-10-PCS group involve the destruction of all or a portion of the pituitary gland using energy, force, or destructive agents. These procedures target the endocrine system and are performed to ablate pituitary tissue for therapeutic or diagnostic purposes. Accurate coding of these destruction procedures matters for inpatient reimbursement because it ensures the procedure performed is captured precisely and supports appropriate case mix classification.

Code Attributes

Character	ICD-10-PCS Category	Code Group Details
0	Section	Medical and Surgical
G	Body System	Endocrine System
5	Operation	Destruction
0	Body Part	Pituitary Gland

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ICD-10-PCS Code For Pituitary Gland: Procedure Code Group Overview

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Pituitary Gland Destruction Procedure Overview

Code Attributes

Character	ICD-10-PCS Category	Code Group Details
0	Section	Medical and Surgical
G	Body System	Endocrine System
5	Operation	Destruction
0	Body Part	Pituitary Gland

When to Use

Use a code from this group when the clinical procedure intentionally destroys pituitary gland tissue as part of treatment or management. These codes apply for inpatient documentation when energy, mechanical force, or a chemical/destructive agent is used to ablate pituitary tissue.

ICD-10-PCS Codes

6 rows

ICD-10-PCS Code	Description
0G500Z3	Destruction of Pituitary Gland using Laser Interstitial Thermal Therapy, Open Approach
0G500ZZ	Destruction of Pituitary Gland, Open Approach
0G503Z3	Destruction of Pituitary Gland using Laser Interstitial Thermal Therapy, Percutaneous Approach
0G503ZZ	Destruction of Pituitary Gland, Percutaneous Approach
0G504Z3	Destruction of Pituitary Gland using Laser Interstitial Thermal Therapy, Percutaneous Endoscopic Approach
0G504ZZ	Destruction of Pituitary Gland, Percutaneous Endoscopic Approach

DRG Codes

13 rows

DRG Code	Description
023	Craniotomy with Major Device Implant or Acute Complex CNS Principal Diagnosis with MCC or Antineoplastic Implant or Epilepsy with Neurostimulator
024	Craniotomy with Major Device Implant or Acute Complex CNS Principal Diagnosis without MCC
025	Craniotomy and Endovascular Intracranial Procedures with MCC
026	Craniotomy and Endovascular Intracranial Procedures with CC
027	Craniotomy and Endovascular Intracranial Procedures without CC/MCC
579	Other Skin, Subcutaneous Tissue and Breast Procedures with MCC
580	Other Skin, Subcutaneous Tissue and Breast Procedures with CC
581	Other Skin, Subcutaneous Tissue and Breast Procedures without CC/MCC
614	Adrenal and Pituitary Procedures with CC/MCC
615	Adrenal and Pituitary Procedures without CC/MCC

Showing 1–10 of 13

Typical Clinical Scenarios

A 45-year-old patient presents to the hospital with a rapidly enlarging pituitary macroadenoma causing visual field deficits and acute compression of the optic chiasm. Neurosurgery performs an open surgical approach to ablate residual pituitary tissue that cannot be safely resected to decompress the optic apparatus and control tumor-related endocrine hypersecretion. Destruction is performed directly on pituitary tissue during the open procedure. Typical codes: 0G500ZZ
A 62-year-old patient with Cushing disease undergoes a planned minimally invasive percutaneous endoscopic procedure to ablate hypersecreting pituitary tissue after prior medical therapy was insufficient. The elective percutaneous endoscopic destruction targets the adenomatous portion of the gland to reduce ACTH production and improve cortisol levels. The procedure is performed with direct destructive technique via a percutaneous endoscopic approach. Typical codes: 0G504ZZ
A 38-year-old patient with recurrent pituitary adenoma after prior transsphenoidal resection returns with persistent hormonal hypersecretion; because repeat resection poses high risk, the team performs a percutaneous laser interstitial thermal therapy to destroy residual pituitary tissue. The minimally invasive percutaneous technique uses focused laser energy to ablate the targeted pituitary tissue as a revision/destructive treatment. Typical codes: 0G503Z3

Related Codes

0G51-PINEAL-BODY-DESTRUCTION

ICD-10-PCS Code For Pineal Body: Procedure Code Group Overview

0G52-ADRENAL-GLAND-LEFT-DESTRUCTION

ICD-10-PCS Code For Adrenal Gland Left: Procedure Code Group Overview

0G53-ADRENAL-GLAND-RIGHT-DESTRUCTION

ICD-10-PCS Code For Adrenal Gland Right: Procedure Code Group Overview

0G54-ADRENAL-GLANDS-DESTRUCTION

ICD-10-PCS Code For Adrenal Glands Bilateral: Procedure Code Group Overview

0G56-CAROTID-BODY-LEFT-DESTRUCTION

ICD-10-PCS Code For Carotid Body Left: Procedure Code Group Overview

0G57-CAROTID-BODY-RIGHT-DESTRUCTION

ICD-10-PCS Code For Carotid Body, Right: Procedure Code Group Overview

0G58-CAROTID-BODIES-DESTRUCTION

ICD-10-PCS Code For Carotid Bodies, Bilateral: Procedure Code Group Overview

0G59-PARA-AORTIC-BODY-DESTRUCTION

ICD-10-PCS Code For Para-Aortic Body: Procedure Code Group Overview

0G5B-COCCYGEAL-GLOMUS-DESTRUCTION

ICD-10-PCS Code for Coccygeal Glomus: Procedure Code Group Overview

0G5C-GLOMUS-JUGULARE-DESTRUCTION

ICD-10-PCS Code For Glomus Jugulare: Procedure Code Group Overview

Showing 1–10 of 21

Frequently Asked Questions

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

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When to Use

ICD-10-PCS Codes

6 rows

ICD-10-PCS Code	Description
0G500Z3	Destruction of Pituitary Gland using Laser Interstitial Thermal Therapy, Open Approach
0G500ZZ	Destruction of Pituitary Gland, Open Approach
0G503Z3	Destruction of Pituitary Gland using Laser Interstitial Thermal Therapy, Percutaneous Approach
0G503ZZ	Destruction of Pituitary Gland, Percutaneous Approach
0G504Z3	Destruction of Pituitary Gland using Laser Interstitial Thermal Therapy, Percutaneous Endoscopic Approach
0G504ZZ	Destruction of Pituitary Gland, Percutaneous Endoscopic Approach

DRG Codes

13 rows

DRG Code	Description
023	Craniotomy with Major Device Implant or Acute Complex CNS Principal Diagnosis with MCC or Antineoplastic Implant or Epilepsy with Neurostimulator
024	Craniotomy with Major Device Implant or Acute Complex CNS Principal Diagnosis without MCC
025	Craniotomy and Endovascular Intracranial Procedures with MCC
026	Craniotomy and Endovascular Intracranial Procedures with CC
027	Craniotomy and Endovascular Intracranial Procedures without CC/MCC
579	Other Skin, Subcutaneous Tissue and Breast Procedures with MCC
580	Other Skin, Subcutaneous Tissue and Breast Procedures with CC
581	Other Skin, Subcutaneous Tissue and Breast Procedures without CC/MCC
614	Adrenal and Pituitary Procedures with CC/MCC
615	Adrenal and Pituitary Procedures without CC/MCC

Showing 1–10 of 13

Typical Clinical Scenarios

A 45-year-old patient presents to the hospital with a rapidly enlarging pituitary macroadenoma causing visual field deficits and acute compression of the optic chiasm. Neurosurgery performs an open surgical approach to ablate residual pituitary tissue that cannot be safely resected to decompress the optic apparatus and control tumor-related endocrine hypersecretion. Destruction is performed directly on pituitary tissue during the open procedure. Typical codes: 0G500ZZ
A 62-year-old patient with Cushing disease undergoes a planned minimally invasive percutaneous endoscopic procedure to ablate hypersecreting pituitary tissue after prior medical therapy was insufficient. The elective percutaneous endoscopic destruction targets the adenomatous portion of the gland to reduce ACTH production and improve cortisol levels. The procedure is performed with direct destructive technique via a percutaneous endoscopic approach. Typical codes: 0G504ZZ
A 38-year-old patient with recurrent pituitary adenoma after prior transsphenoidal resection returns with persistent hormonal hypersecretion; because repeat resection poses high risk, the team performs a percutaneous laser interstitial thermal therapy to destroy residual pituitary tissue. The minimally invasive percutaneous technique uses focused laser energy to ablate the targeted pituitary tissue as a revision/destructive treatment. Typical codes: 0G503Z3

Related Codes

0G51-PINEAL-BODY-DESTRUCTION

ICD-10-PCS Code For Pineal Body: Procedure Code Group Overview

0G52-ADRENAL-GLAND-LEFT-DESTRUCTION

ICD-10-PCS Code For Adrenal Gland Left: Procedure Code Group Overview

0G53-ADRENAL-GLAND-RIGHT-DESTRUCTION

ICD-10-PCS Code For Adrenal Gland Right: Procedure Code Group Overview

0G54-ADRENAL-GLANDS-DESTRUCTION

ICD-10-PCS Code For Adrenal Glands Bilateral: Procedure Code Group Overview

0G56-CAROTID-BODY-LEFT-DESTRUCTION

ICD-10-PCS Code For Carotid Body Left: Procedure Code Group Overview

0G57-CAROTID-BODY-RIGHT-DESTRUCTION

ICD-10-PCS Code For Carotid Body, Right: Procedure Code Group Overview

0G58-CAROTID-BODIES-DESTRUCTION

ICD-10-PCS Code For Carotid Bodies, Bilateral: Procedure Code Group Overview

0G59-PARA-AORTIC-BODY-DESTRUCTION

ICD-10-PCS Code For Para-Aortic Body: Procedure Code Group Overview

0G5B-COCCYGEAL-GLOMUS-DESTRUCTION

ICD-10-PCS Code for Coccygeal Glomus: Procedure Code Group Overview

0G5C-GLOMUS-JUGULARE-DESTRUCTION

ICD-10-PCS Code For Glomus Jugulare: Procedure Code Group Overview

Showing 1–10 of 21

Frequently Asked Questions

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

Published by

Trek Health powers OpenPayer with a leading commercial payer intelligence platform, seamlessly converting fragmented payer data into actionable insights for provider organizations.

ICD-10-PCS Code For Pituitary Gland: Procedure Code Group Overview

Sign up for ICD-10-PCS Code For Pituitary Gland: Procedure Code Group Overview policy alerts

Pituitary Gland Destruction Procedure Overview

Code Attributes

ICD-10-PCS Code For Pituitary Gland: Procedure Code Group Overview

Sign up for ICD-10-PCS Code For Pituitary Gland: Procedure Code Group Overview policy alerts

Pituitary Gland Destruction Procedure Overview

Code Attributes

When to Use

ICD-10-PCS Codes

DRG Codes

Typical Clinical Scenarios

Related Codes

Which body system and operation does ICD-10-PCS code group 0G50 describe?

What are example ICD-10-PCS codes in the 0G50 pituitary gland destruction group?

Why is accurate coding within ICD-10-PCS 0G50 important for inpatient reimbursement?

Which DRGs may be related to procedures in the 0G50 pituitary destruction group?

What approaches and technologies are distinguished within the 0G50 codes?

References

When to Use

ICD-10-PCS Codes

DRG Codes

Typical Clinical Scenarios

Related Codes

Which body system and operation does ICD-10-PCS code group 0G50 describe?

What are example ICD-10-PCS codes in the 0G50 pituitary gland destruction group?

Why is accurate coding within ICD-10-PCS 0G50 important for inpatient reimbursement?

Which DRGs may be related to procedures in the 0G50 pituitary destruction group?

What approaches and technologies are distinguished within the 0G50 codes?

References