ICD-10-PCS Code For Brain: Procedure Code Group Overview

The International Classification of Diseases, Tenth Revision, Procedure Coding System (ICD-10-PCS) code group 00B0 includes procedures performed to excise portions of the brain in the central nervous system and cranial nerves. These ICD-10-PCS codes are used for inpatient documentation when a portion of brain tissue is surgically removed for reasons such as tumor resection, hematoma evacuation, or removal of necrotic or epileptogenic tissue. Accurate coding within the ICD-10-PCS 00B0 group is essential for proper inpatient reimbursement, as it captures the specific procedure performed and supports clinical documentation accuracy.

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Brain Excision Procedure Overview

This group includes procedures that involve cutting out or off a portion of the brain and targets the central nervous system and cranial nerves. These procedures remove abnormal tissue such as tumors, necrotic areas, or epileptogenic foci from the brain. Accurate coding of brain excision procedures ensures inpatient records reflect the operative intervention and supports appropriate reimbursement and case mix assignment.

Code Attributes

Character	ICD-10-PCS Category	Code Group Details
0	Section	Medical and Surgical
0	Body System	Central Nervous System and Cranial Nerves
B	Operation	Excision
0	Body Part	Brain

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ICD-10-PCS Code For Brain: Procedure Code Group Overview

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Brain Excision Procedure Overview

Code Attributes

Character	ICD-10-PCS Category	Code Group Details
0	Section	Medical and Surgical
0	Body System	Central Nervous System and Cranial Nerves
B	Operation	Excision
0	Body Part	Brain

When to Use

Use a code from this group when a surgeon surgically removes a portion of the brain during an inpatient admission. Codes apply when the operation is excision of brain tissue for indications such as tumor removal, hematoma evacuation, or resection of pathologic brain tissue.

ICD-10-PCS Codes

6 rows

ICD-10-PCS Code	Description
00B00ZX	Excision of Brain, Open Approach, Diagnostic
00B00ZZ	Excision of Brain, Open Approach
00B03ZX	Excision of Brain, Percutaneous Approach, Diagnostic
00B03ZZ	Excision of Brain, Percutaneous Approach
00B04ZX	Excision of Brain, Percutaneous Endoscopic Approach, Diagnostic
00B04ZZ	Excision of Brain, Percutaneous Endoscopic Approach

DRG Codes

15 rows

DRG Code	Description
023	Craniotomy with Major Device Implant or Acute Complex CNS Principal Diagnosis with MCC or Antineoplastic Implant or Epilepsy with Neurostimulator
024	Craniotomy with Major Device Implant or Acute Complex CNS Principal Diagnosis without MCC
025	Craniotomy and Endovascular Intracranial Procedures with MCC
026	Craniotomy and Endovascular Intracranial Procedures with CC
027	Craniotomy and Endovascular Intracranial Procedures without CC/MCC
820	Lymphoma and Leukemia with Major O.R. Procedures with MCC
821	Lymphoma and Leukemia with Major O.R. Procedures with CC
822	Lymphoma and Leukemia with Major O.R. Procedures without CC/MCC
826	Myeloproliferative Disorders or Poorly Differentiated Neoplasms with Major O.R. Procedures with MCC
827	Myeloproliferative Disorders or Poorly Differentiated Neoplasms with Major O.R. Procedures with CC

Showing 1–10 of 15

Typical Clinical Scenarios

An adult patient presents to the emergency department with sudden-onset severe headache, decreased consciousness, and focal neurologic deficits. Neuroimaging demonstrates a large intracerebral hemorrhage with mass effect and midline shift; the neurosurgical team performs an open craniotomy to excise and evacuate the hematoma and devitalized brain tissue to reduce intracranial pressure and prevent herniation. This is an acute, life-saving inpatient excision of brain tissue performed via an open approach. Typical codes: 00B00ZZ
A middle-aged patient with a known low-grade glioma undergoes a planned surgical resection to remove a portion of tumor-bearing brain tissue after preoperative mapping and functional assessment. The neurosurgeon performs a percutaneous endoscopic-assisted excision to maximize tissue removal while minimizing disruption to surrounding cortex during an elective inpatient admission for tumor resection and postoperative monitoring. Typical codes: 00B04ZZ
A patient with medically refractory focal epilepsy undergoes a targeted percutaneous excision of an epileptogenic focus identified on invasive monitoring after prior less-invasive interventions failed to control seizures. The procedure is performed percutaneously in an inpatient setting to remove the small area of pathologic brain tissue responsible for seizure generation. Typical codes: 00B03ZZ

Related Codes

00B1-CEREBRAL-MENINGES-EXCISION

ICD-10-PCS Code For Cerebral Meninges: Procedure Code Group Overview

00B2-DURA-MATER-EXCISION

ICD-10-PCS Code For Dura Mater: Procedure Code Group Overview

00B6-CEREBRAL-VENTRICLE-EXCISION

ICD-10-PCS Code For Cerebral Ventricle: Procedure Code Group Overview

00B7-CEREBRAL-HEMISPHERE-EXCISION

ICD-10-PCS Code For Cerebral Hemisphere: Procedure Code Group Overview

00B8-BASAL-GANGLIA-EXCISION

ICD-10-PCS Code For Basal Ganglia: Procedure Code Group Overview

00B9-THALAMUS-CUTTING-OUT-THALAMUS-EXCISION

ICD-10-PCS Code For Thalamus: Procedure Code Group Overview

00BA-HYPOTHALAMUS-EXCISION

ICD-10-PCS Code For Hypothalamus: Procedure Code Group Overview

00BB-PONS-EXCISION

ICD-10-PCS Code For Pons: Procedure Code Group Overview

00BC-CEREBELLUM-EXCISION

ICD-10-PCS Code For Cerebellum: Procedure Code Group Overview

00BD-MEDULLA-OBLONGATA-EXCISION

ICD-10-PCS Code For Medulla Oblongata: Procedure Code Group Overview

Showing 1–10 of 26

Frequently Asked Questions

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

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When to Use

ICD-10-PCS Codes

6 rows

ICD-10-PCS Code	Description
00B00ZX	Excision of Brain, Open Approach, Diagnostic
00B00ZZ	Excision of Brain, Open Approach
00B03ZX	Excision of Brain, Percutaneous Approach, Diagnostic
00B03ZZ	Excision of Brain, Percutaneous Approach
00B04ZX	Excision of Brain, Percutaneous Endoscopic Approach, Diagnostic
00B04ZZ	Excision of Brain, Percutaneous Endoscopic Approach

DRG Codes

15 rows

DRG Code	Description
023	Craniotomy with Major Device Implant or Acute Complex CNS Principal Diagnosis with MCC or Antineoplastic Implant or Epilepsy with Neurostimulator
024	Craniotomy with Major Device Implant or Acute Complex CNS Principal Diagnosis without MCC
025	Craniotomy and Endovascular Intracranial Procedures with MCC
026	Craniotomy and Endovascular Intracranial Procedures with CC
027	Craniotomy and Endovascular Intracranial Procedures without CC/MCC
820	Lymphoma and Leukemia with Major O.R. Procedures with MCC
821	Lymphoma and Leukemia with Major O.R. Procedures with CC
822	Lymphoma and Leukemia with Major O.R. Procedures without CC/MCC
826	Myeloproliferative Disorders or Poorly Differentiated Neoplasms with Major O.R. Procedures with MCC
827	Myeloproliferative Disorders or Poorly Differentiated Neoplasms with Major O.R. Procedures with CC

Showing 1–10 of 15

Typical Clinical Scenarios

An adult patient presents to the emergency department with sudden-onset severe headache, decreased consciousness, and focal neurologic deficits. Neuroimaging demonstrates a large intracerebral hemorrhage with mass effect and midline shift; the neurosurgical team performs an open craniotomy to excise and evacuate the hematoma and devitalized brain tissue to reduce intracranial pressure and prevent herniation. This is an acute, life-saving inpatient excision of brain tissue performed via an open approach. Typical codes: 00B00ZZ
A middle-aged patient with a known low-grade glioma undergoes a planned surgical resection to remove a portion of tumor-bearing brain tissue after preoperative mapping and functional assessment. The neurosurgeon performs a percutaneous endoscopic-assisted excision to maximize tissue removal while minimizing disruption to surrounding cortex during an elective inpatient admission for tumor resection and postoperative monitoring. Typical codes: 00B04ZZ
A patient with medically refractory focal epilepsy undergoes a targeted percutaneous excision of an epileptogenic focus identified on invasive monitoring after prior less-invasive interventions failed to control seizures. The procedure is performed percutaneously in an inpatient setting to remove the small area of pathologic brain tissue responsible for seizure generation. Typical codes: 00B03ZZ

Related Codes

00B1-CEREBRAL-MENINGES-EXCISION

ICD-10-PCS Code For Cerebral Meninges: Procedure Code Group Overview

00B2-DURA-MATER-EXCISION

ICD-10-PCS Code For Dura Mater: Procedure Code Group Overview

00B6-CEREBRAL-VENTRICLE-EXCISION

ICD-10-PCS Code For Cerebral Ventricle: Procedure Code Group Overview

00B7-CEREBRAL-HEMISPHERE-EXCISION

ICD-10-PCS Code For Cerebral Hemisphere: Procedure Code Group Overview

00B8-BASAL-GANGLIA-EXCISION

ICD-10-PCS Code For Basal Ganglia: Procedure Code Group Overview

00B9-THALAMUS-CUTTING-OUT-THALAMUS-EXCISION

ICD-10-PCS Code For Thalamus: Procedure Code Group Overview

00BA-HYPOTHALAMUS-EXCISION

ICD-10-PCS Code For Hypothalamus: Procedure Code Group Overview

00BB-PONS-EXCISION

ICD-10-PCS Code For Pons: Procedure Code Group Overview

00BC-CEREBELLUM-EXCISION

ICD-10-PCS Code For Cerebellum: Procedure Code Group Overview

00BD-MEDULLA-OBLONGATA-EXCISION

ICD-10-PCS Code For Medulla Oblongata: Procedure Code Group Overview

Showing 1–10 of 26

Frequently Asked Questions

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

Published by

Trek Health powers OpenPayer with a leading commercial payer intelligence platform, seamlessly converting fragmented payer data into actionable insights for provider organizations.

ICD-10-PCS Code For Brain: Procedure Code Group Overview

Sign up for ICD-10-PCS Code For Brain: Procedure Code Group Overview policy alerts

Brain Excision Procedure Overview

Code Attributes

ICD-10-PCS Code For Brain: Procedure Code Group Overview

Sign up for ICD-10-PCS Code For Brain: Procedure Code Group Overview policy alerts

Brain Excision Procedure Overview

Code Attributes

When to Use

ICD-10-PCS Codes

DRG Codes

Typical Clinical Scenarios

Related Codes

Which body system and operation does the 00B0 code group represent?

What procedures are included under the codes `00B00ZX` to `00B04ZZ`?

For what clinical reasons are brain excision procedures coded in 00B0 typically performed?

How does accurate coding within the 00B0 group affect inpatient records and reimbursement?

Which related DRGs are commonly associated with 00B0 brain excision procedures?

References

When to Use

ICD-10-PCS Codes

DRG Codes

Typical Clinical Scenarios

Related Codes

Which body system and operation does the 00B0 code group represent?

What procedures are included under the codes `00B00ZX` to `00B04ZZ`?

For what clinical reasons are brain excision procedures coded in 00B0 typically performed?

How does accurate coding within the 00B0 group affect inpatient records and reimbursement?

Which related DRGs are commonly associated with 00B0 brain excision procedures?

References