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    v1.0.28
    OpenPayerPolicy UpdatesPharmacy & Specialty DrugsMolina Saphnelo Prior Auth Coverage | OpenPayer
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    CurrentMolina HealthcarePolicy C21970-A

    Saphnelo (anifrolumab-fnia) Drug and Biologic Coverage Criteria

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    Governs prior authorization and coverage of intravenous Saphnelo for adults with moderate to severe systemic lupus erythematosus receiving standard therapy, including clinical criteria, documentation, prescriber qualifications, dosing, and administration-site requirements.

    Policy Summary
    PayerMolina Healthcare
    PolicySaphnelo (anifrolumab-fnia) Drug and Biologic Coverage Criteria
    Policy CodePolicy C21970-A
    Change TypeNo material clinical or coverage changes
    Effective DateDecember 28, 2025
    Next Review DateOctober 1, 2026
    Key ActionEnsure Saphnelo is prescribed by or in consultation with a board-certified rheumatologist or a physician who specializes in treating systemic autoimmune diseases.
    SourceLink
    POLICY UPDATE CHANGES

    No material clinical or coverage changes in this revision.

    18+Minimum member age
    300 mgDose
    Every 4 weeksFrequency
    6 monthsInitial authorization

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    12 monthsContinuation authorization
    CNS lupus or nephritisExcluded disease manifestations