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    v1.0.28
    OpenPayerPolicy UpdatesPharmacy & Specialty DrugsCareSource Drug List Coverage & Prior Auth | OpenP…
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    OpenPayer is powered by Trek Health's payer performance platform. Trek continuously ingests, validates, and normalizes Transparency in Coverage data alongside payer policies and other commercial payer data to create a structured payer intelligence foundation. OpenPayer uses this foundation to deliver personalized search results, dynamically generated policy pages, and tailored policy monitoring based on each user's payers, specialties, billing codes, and areas of interest. The same intelligence powers broader payer performance workflows, including reimbursement benchmarking, contract evaluation, payer negotiations, and financial decision-making.

    CurrentCareSourcePolicy N/A

    List of Covered Drugs (Drug List) — Coverage Criteria

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    Defines which drugs, OTC products, and non-drug items are covered under HAP CareSource MI Coordinated Health and explains rules, restrictions, and member/provider actions for obtaining covered drugs.

    Policy Summary
    PayerCareSource
    PolicyList of Covered Drugs (Drug List) — Coverage Criteria
    Policy CodePolicy N/A
    Change TypeNo material changes noted
    Effective DateN/A
    Last ReviewSep 11, 2025
    Next Review DateN/A
    Key ActionObtain prior authorization from HAP CareSource before dispensing drugs flagged 'PA' to avoid denial.
    SourceLink
    POLICY UPDATE CHANGES

    No material clinical or coverage changes in this revision.

    05/18/2026Drug list last updated
    30-dayTemporary new-member supply
    90-dayNew-member transition period
    1-833-230-2057Member Services
    PA; MO; QL; NDSAuth/restriction codes
    $0Copay when rules followed

    Coverage Criteria and General Rules

    General coverage conditions

    Covered when ALL of the following are met

    Medical necessity and network fill: Drug is covered if the prescriber states it is medically necessary, HAP CareSource MI Coordinated Health agrees it is medically necessary, and the member fills the prescription at a HAP CareSource MI Coordinated Health network pharmacy.

    See page 15 onward (Drug List) for covered products and network pharmacy definition.

    New member temporary coverage

    Temporary transition supply for new members

    30-day temporary supply: Plan may cover a temporary 30-day supply during the first 90 days of membership when the drug is not on the Drug List, the plan rules limit the amount ordered, the drug requires prior authorization, or the drug is subject to step therapy.30 days

    If prescription is written for fewer days, multiple refills may be allowed to reach the 30-day supply; nursing home residents may qualify for a one-time 31-day supply if needed.

    Policy Summary
    PayerCareSource
    PolicyList of Covered Drugs (Drug List) — Coverage Criteria
    Policy CodePolicy N/A
    Change TypeNo material changes noted
    Effective DateN/A
    Last ReviewSep 11, 2025
    Next Review DateN/A
    Key ActionObtain prior authorization from HAP CareSource before dispensing drugs flagged 'PA' to avoid denial.
    SourceLink
    On This Page
    Coverage Criteria and General RulesFormulary Codes, Abbreviations, and Quantity Limits (coding references)What Providers and Pharmacies Must DoStep Therapy Rules and TablesQuantity Limits by Product and FormulationSite-of-Care Routing and Coverage ConsiderationsBackground and ScopeDefinitions and Table AbbreviationsBiosimilars and Benefit Routing

    General coverage rules

    Covered when plan rules for the specific drug are met as listed in the Drug List

    Formulary Coverage Requirements: Coverage depends on the specific drug listing and its listed requirements (for example: prior authorization (PA), step therapy (ST), quantity limits (QL), limited availability (LA), or Medicaid-only designation (MCD/B/D PA)).

    Consult the Drug List table legend and the specific drug row for required actions and documentation.

    Covered when listing conditions are met

    Coverage entries for listed anti-infectives include tier level, and may be subject to utilization controls. Coverage is indicated by listing and tier but constrained by the following controls where specified.

    Formulary listing with controls: Individual anti-infective drug entries are listed with a Tier Level and may include one or more utilization controls: PA (prior authorization), MO (medical override/medical-only), QL (quantity limit), NDS (non-extended days' supply) or LA (limited availability). Coverage is available when the specified administrative requirements on the drug row are satisfied.

    See the drug-specific row for exact controls and QL values.

    Sample coverage criteria by drug (excerpt)

    Drugs listed are covered when member/claim meets payer's utilization controls indicated on each row (examples below reflect excerpted entries).

    Example - AUGTYRO ORAL CAPSULE 160 MG: Coverage requires prior authorization (PA) and a quantity limit of 60 per 30 days; NDS is noted on the formulary row.QL 60/30 days

    Follow PA submission process and provide clinical rationale as requested.

    Example - AUGTYRO ORAL CAPSULE 40 MG: Coverage requires prior authorization (PA) and a quantity limit of 240 per 30 days; some presentations may also indicate B/D PA or MO.QL 240/30 days

    Confirm benefit/setting (B/D PA) when applicable.

    Example - BOSULIF ORAL CAPSULE/TABLET: Coverage requires prior authorization (PA) and medical-only (MO) designation; quantity limits vary by strength (e.g., QL 180 per 30 days) and NDS may apply.varies by formulation

    Submit PA with supporting documentation for requested strength/quantity.

    Example - DASATINIB oral tablets: Coverage requires prior authorization (PA), may require MO, and has a quantity limit of 30 per 30 days; NDS may be indicated.QL 30/30 days

    Provide clinical indication and prior therapy information per PA requirements.

    Covered with utilization management

    Coverage entries in this segment are conditional and include utilization management elements such as prior authorization and quantity limits. Coverage stance is per drug as noted.

    Per-drug conditional coverage: Each listed drug includes conditions (PA, MO, LA, QL, NDS) that govern coverage; meeting the listed conditions on the drug row is required for coverage.

    Provider must consult the full policy and the specific drug row for clinical medical necessity criteria and PA requirements.

    Formulary coverage with utilization controls

    Coverage is defined per drug/formulation with controls; covered status is implied but subject to listed restrictions

    Formulary entry conditions: A drug is listed with a tier level and may be covered only when payer-specified utilization controls (PA, MO, QL, LA, NDS) shown for that formulation are met.

    Follow PA, QL and MO instructions and include documentation required by the drug row.

    Covered with utilization controls

    Drugs are covered subject to the listed utilization controls (examples below reflect the table entries):

    General formulary coverage condition: Coverage is provided when payer-specified utilization controls for the drug/formulation (for example: MO, PA, QL, ST, NDS) are satisfied as shown in the table.See QL values per drug

    Prescribers must consult the drug row for specific limits and required documentation.

    Coverage conditioned on UM compliance

    Coverage for listed drugs is provided when the utilization management requirements and quantity limits displayed for each formulation are satisfied.

    UM compliance: Member/prescriber meets all required flags shown for the specific product (obtain PA if listed; secure MO where listed; follow ST if listed; remain within the specified QL; comply with any NDS/LA requirements).as listed per product

    Failure to satisfy the listed UM requirements may result in denial or non-coverage.

    Drugs that are removed from the market or found to be unsafe may be taken off the Drug List immediately and will not be covered. If a member is taking a drug that has been removed, the Plan will send notice after the change and the member should contact their prescriber for management. (See Drug List change rules and member notice provisions.)

    Some products are designated NDS (Non-Extended Days' Supply) and are limited to a 30‑day supply. Failure to dispense or request coverage in accordance with the NDS/30‑day limit may result in non‑coverage.

    This extract does not include additional exclusion/exception text for other product categories. Refer to the full Drug List and related policy sections for complete exclusion details and exception processes.

    Within this excerpt there are no other explicit exclusion conditions listed. Coverage exclusions applicable to specific products are governed by the full formulary entries and accompanying legend.

    No explicit exclusion conditions are provided in the excerpted rows shown; product-level restrictions (PA, B/D PA, MO, NDS, QL) control coverage rather than standalone exclusion language in this segment.

    This excerpt does not identify explicit exclusions for the listed oncology and related products. Any exclusions would be indicated elsewhere in the full Drug List or policy documentation.

    No explicit exclusions are noted in this excerpt for the listed behavioral health and injectable products; coverage is governed by the utilization controls and flags shown in the table.

    The excerpt does not list explicit exclusions. Where exclusions apply, they are managed through the full formulary and associated policy sections rather than within these sample table rows.

    If required approvals such as Prior Authorization (PA) are not obtained where indicated on the Drug List, the Plan may not cover the drug. Providers should verify PA requirements and submit the necessary documentation before dispensing to avoid denial.

    This block is a placeholder in the inventory and the excerpt offers no additional text. Consult the full Drug List or policy for any further statements related to this entry.

    There are no explicit 'Not Medically Necessary' statements in this excerpt. Coverage decisions are presented as conditional on meeting utilization controls (PA, ST, QL, MO, NDS) shown for each product.

    This excerpt does not contain explicit 'Not Medically Necessary' language. Determinations of medical necessity follow the Plan's procedures and the drug-specific coverage rules listed in the full formulary.

    Not specified in the provided excerpt. Medical necessity and 'not medically necessary' determinations are addressed in the Plan's broader clinical policies and the full Drug List documentation.

    The excerpt does not include explicit 'Not Medically Necessary' conditions. In practice, therapies that exceed stated quantity limits or lack required prior authorization or step therapy where applicable would not be approved.

    Not explicitly stated in this excerpt. Coverage denials generally follow when utilization management requirements (PA, ST) are not met or when quantity limits (QL) are exceeded without appropriate documentation or overrides.

    Formulary Codes, Abbreviations, and Quantity Limits (coding references)

    Formulary action codesmixed
    MCDNon-Part D drugs or OTC items that are covered by Medicaid only
    B/D PAThis prescription drug may be covered under Medicare Part B or D depending upon the circumstances; information about use/setting may be required
    LALimited availability — may be available only at certain pharmacies
    MOMail-Order Drug — available through mail-order service and retail network pharmacies
    NDSNon-Extended Days' Supply — limited to 30 days' supply at retail or mail-order
    PAPrior Authorization required — approval must be obtained before filling
    QLQuantity Limit — the Plan limits the amount of the drug covered
    STStep Therapy required — trial of specified drugs may be required first
    VVaccine provided at no cost when used per CDC/ACIP recommendations
    Quantity limit notations present in tablemixed
    QL (84 per 56 days)Quantity limit example for azithromycin or related entry as shown
    QL (20 per 10 days)Quantity limit example (e.g., DIFICID / fidaxomicin)
    QL (224 per 56 days)Quantity limit example (e.g., TOBI PODHALER mapping)
    QL (280 per 28)Quantity limit example for tobramycin mapping (example formatting shown)
    QL (9 per 30 days)Quantity limit example for vancomycin IV piggyback or related entry
    QL (80 per 10 days)Quantity limit example for vancomycin IV piggyback presentation
    Drug entries (no explicit billing codes in excerpt)mixed
    N/ANo explicit CPT/HCPCS/ICD-10/NDC codes listed in this excerpt; entries are drug name, presentation, and utilization controls.
    Utilization abbreviationsmixed
    NDSNon-Extended Days' Supply — notation shown in list
    PAPrior Authorization — approval required before coverage
    MOMedical Oncology or Mail-Order/medical-only modifier (as listed)
    QLQuantity Limit — numeric cap shown (value specified separately)
    LALimited Access — may be available only at certain pharmacies
    B/D PAMay be covered under Medicare Part B or D depending on setting/use; additional information may be required
    Quantity limits (examples)mixed
    0.5 per 28 daysQuantity limit example for INVEGA SUSTENNA (0.5 per 28 days)
    150 per 30 daysQuantity limit example for INVEGA SUSTENNA (150 per 30 days)
    Additional QL entriesmixed
    2 per 28 daysQuantity limit for some long-acting injectables (e.g., risperidone microspheres)
    120 per 30 daysQuantity limit example (e.g., RALDESY)
    Quantity limits referenced — examples
    Examples shown in headerQL (96 per 30 days); QL (120 per 30 days)
    Itraconazole exampleitraconazole oral capsule — MO; QL (120 per 30 days)
    Amphotericin B liposome examplePA; MO; QL (96 per 30 days); NDS
    Quantity limits — examples
    Common per-period formatsExamples: QL (28 per 28 days); QL (56 per 28 days); QL (84 per 28 days); QL (120 per 30 days)
    Repeated small-limit exampleQL (11 per 30 days) appears on multiple antiviral entries
    MAVYRET examplesMAVYRET ORAL PELLETS — QL (168 per 28 days); MAVYRET ORAL TABLET — QL (84 per 28 days)
    Quantity limits examples (short intervals)
    Short interval QL examplesQL (30 per 10 days); QL (20 per 10 days)
    Monthly examplesQL (60 per 30 days)
    Longer interval inhalation exampleTOBI PODHALER — QL (224 per 56 days)
    Quantity limits examples — varied across table
    Large IV piggyback rangesVANCOMYCIN IV piggyback examples: QL (4000 per 10 days); QL (80 per 10 days); QL (1000 per 10 days)
    Tobramycin injection examplestobramycin sulfate injection recon soln — QL (9 per 14 days); alternate QL (10 per 10 days)
    Meropenem IV examplesmeropenem IV recon soln — QL (30 per 10 days) or QL (60 per 30 days) depending on row
    Quantity limits (examples) per drug row
    Per-row QL examplesMultiple oncology/antineoplastic rows show QL per strength such as 60 per 30 days; 240 per 30 days; 112 per 28 days
    Bortezomib exampleBORTEZOMIB injection recon soln — QL (30 per 30 days) or B/D PA/NDS variants
    Bosulif examplesBOSULIF ORAL TABLET — QL (180 per 30 days); BOSULIF TABLET (400/500 mg) — QL (56 per 28 days)
    Quantity limits examples — e.g., 120/30, 21/28, 1260/30
    High/varied QL examplesGemcitabine IV solution — QL (120 per 30 days); IMBRUVICA 70 mg — QL (28 per 28 days)
    Lumakras examplesLUMAKRAS various strengths shown with QL — 240/30; 120/30; 90/30 depending on strength
    LUNSUMIO exampleLUNSUMIO — QL (1260 per 30 days)
    Quantity limits examples — 240/30; 120/30; 90/30; 1260/30
    Lumakras strength-specific limitsLUMAKRAS 120 mg — QL (240 per 30 days); 240 mg — QL (120 per 30 days); 320 mg — QL (90 per 30 days)
    LUNSUMIO repeatLUNSUMIO — QL (1260 per 30 days)
    LYNPARZA exampleLYNPARZA — QL (120 per 30 days)
    Quantity limits examples — 224/28; 120/30; 28/28
    High QL oncology examplesRYDAPT — QL (224 per 28 days); RYLAZE — QL (120 per 30 days); sunitinib malate — QL (28 per 28 days)
    VENCLEXTA exampleVENCLEXTA 100 mg — QL (180 per 30 days)
    ROZLYTREK examplesROZLYTREK oral capsule 100 mg — QL (150 per 30 days); alternate QL entries exist by strength
    Quantity limits examples across entries (10/30 to 1200/30)
    Observed high maximumsExamples include QL (1200 per 30 days); QL (720 per 30 days); QL (360 per 30 days); QL (60 per 30 days)
    Briviact examplesBRIVIACT IV — QL (600 per 30 days); BRIVIACT oral/tablet listings include 60/30, 300/30, 600/30 depending on formulation
    Clobazam/gabapentin high QLsclobazam — QL (480/30) or 360/30; gabapentin solution — QL (2160 per 30 days)
    Quantity limits examples — QL 8/28, 30/30, 120/30, 24/180
    Common small-to-large QLsExamples include QL (8 per 28 days); QL (30 per 30 days); QL (120 per 30 days); QL (24 per 180 days)
    AUSTEDO XR titration kitAUSTEDO XR TITRATION KT — QL (28 per 180 days); other formulations QL (30 per 30 days)
    Valproic acid solutionValproic acid oral solution — QL (1100 per 30 days) for specified concentrations
    Quantity limits examples — 10/30, 60/30, 360/30, 240/30, 900/30
    Opioid analgesic rangesExamples: fentanyl patch — QL (10 per 30 days) (alternate mapping QL 2400/30); hydrocodone-acetaminophen solution — QL (5550 per 30 days) with alternate QL (180 per 30 days)
    Hydromorphone ERhydromorphone ER 24 hr — QL (60 per 30 days)
    Methadone rangesmethadone formulations — QL examples include 90/30; 120/30; 240/30; 900/30; 1200/30 depending on presentation
    Observed quantity limits — up to 1200/30
    Highest observed QLsEntries include QL up to 1200 per 30 days (e.g., diazepam oral solution QL 1200/30) — observed maximums in table reach 1200/30
    INVEGA examplesINVEGA SUSTENNA/TRINZA IM formulations show fractional QLs (e.g., 0.5 per 28 days; 0.88 per 90 days) and higher per‑period caps where listed
    ASIMTUFII examplesASIMTUFII IM formulations show QL examples such as 30/30; 60/30; 4.8/365; 1.6/28; 3.2/56
    Common QL examples — 30/30, 60/30, 2/28, 28/365
    Frequent QL patternsCommon QL examples include QL (30 per 30 days); QL (60 per 30 days); QL (2 per 28 days); QL (28 per 365 days)
    Risperidone microspheresrisperidone microspheres IM extended — QL (2 per 28 days)
    Yearly caps examplesSome oral agents show annual caps such as QL (28 per 365 days) or QL (14 per 365 days)

    What Providers and Pharmacies Must Do

    Note

    Member ID — present card at pharmacy

    Present the member's ID card at the pharmacy when filling prescriptions — pharmacies will verify eligibility and plan coverage before dispensing.

    • Call Member Services at 1-833-230-2057 (TTY: 1-833-711-4711 or 711) for help with prior authorization, exceptions, appeals, or questions about the Drug List.
    Prior Authorization

    Prior Authorization Required

    Prior authorization (PA) is required where the table or drug entry lists PA, B/D PA, or similar PA markings. Providers must obtain authorization from CareSource before dispensing or the Plan may deny coverage.

    • Prior authorization is required for many specialty/oncology agents and select anti-infectives, injectables, and certain formulations (see table entries marked PA, B/D PA, PA; MO, etc.).
    • Failure to obtain required PA may result in non-coverage or claim denial.
    • Verify PA requirements for the exact NDC/formulation before dispensing — entries sometimes indicate PA for a specific formulation only.
    Prior Authorization

    Prior Authorization — formulary‑mandated (B/D PA)

    Some drugs are formulary‑mandated or otherwise require prior authorization as a condition of coverage (B/D PA entries indicate drugs that may be billed to Part B or Part D depending on setting and documentation).

    • If an entry shows B/D PA, submit documentation describing the drug use and setting so the Plan can determine Part B vs Part D coverage.
    • Formulary-mandated PA means the drug may not be covered without prior approval even if clinically appropriate.
    Prior Authorization

    Prior Authorization and Medical‑Only (MO) Flags

    Certain drugs carry Medical‑Only (MO) flags or limited‑availability (LA) routing; where MO appears, medical benefit review or a medical claim route may be required instead of retail pharmacy billing.

    • When MO or LA is shown, contact the Plan for guidance on medical benefit billing or site‑of‑care requirements.
    • Medical override/review (MO) may be required to authorize coverage.
    • Some entries include MO plus PA — both actions must be completed as indicated.
    Prior Authorization

    Prior Authorization Required for Some Anti‑infectives

    Some anti‑infectives and injectables are subject to PA, MO, QL, and/or NDS. Review each anti‑infective entry for its specific controls before dispensing.

    • Examples in the anti‑infective sections include amphotericin formulations, cephalosporins, vancomycin, tobramycin, and others marked PA; MO; QL; NDS.
    • Quantity limits (QL) for IV/infusion products are common and must be observed; exceeding QL may require documentation and can trigger denial.
    Note

    Legend Required — table symbol definitions

    Table entries use symbols (PA, MO, QL, ST, NDS, LA, B/D PA, MCD) to indicate required actions and utilization controls. Refer to the table legend at the start of the drug list for definitions.

    • Legend definitions: PA = Prior Authorization; MO = Mail‑Order/Medical routing or Medical‑only; QL = Quantity Limit; ST = Step Therapy; NDS = Non‑Extended Days' Supply; LA = Limited Availability; B/D PA = Part B/Part D determination; MCD = Medicaid (non‑Part D) item.
    Note

    Follow Table‑Specified Controls and Name‑of‑Drug Mapping

    Follow all table‑specified controls (PA, MO, QL, ST, NDS, LA, B/D PA) exactly as listed for each drug entry. When a table row shows 'Name of Drug = [other drug]', interpret that as an alternate mapping and apply the controls shown (e.g., Name of Drug = PAXLOVID indicates mapping to the listed OTC or antiviral entry).

    • If a row lists 'Name of Drug = [other drug]', the restrictions and controls for the referenced product apply.
    • Providers should not assume controls are the same across formulations; check the exact listed formulation and its controls.
    Documentation Required

    Quantity Limits (QL) and Documentation

    Quantity limits (QL) are specified for many drugs and formulations. If a requested quantity exceeds the published QL, include supporting clinical documentation with the PA request; requests to exceed QL may be denied without justification.

    • Examples: various oral and IV oncology agents and anti‑infectives list QL values (e.g., QL (28 per 28 days), QL (120 per 30 days), etc.).
    • Quantity limit documentation should state the clinical rationale and duration requested.
    • Exceeding QL without documentation may trigger denial or require an exception request.
    Documentation Required

    Prior Authorization Documentation Required

    Prior authorization documentation is required when PA, B/D PA, B/D PA; MO or similar markers appear. Include clinical justification, supporting prescriber statement, relevant prior therapies (for ST), and quantity/duration rationale.

    • The prescriber's supporting statement is required for exception and expedited requests — see Member Services contact information.
    • Keep copies of submitted documentation; the Plan may request additional information during review.
    Documentation Required

    Quantity Limit Documentation — supporting evidence required

    Quantity‑limit and utilization management requests may require additional supporting documentation. Examples include justification to exceed a QL, evidence of failure/intolerance for step‑therapy requirements, or clinical reasons for non‑standard days' supply.

    • Examples cited in the drug list include QL (e.g., 96 per 30 days, 240 per 30 days) where documentation can support a higher quantity.
    • Document prior trials, lab results, and prescriber rationale when requesting overrides.
    Step Therapy

    Step Therapy (ST) — try required agents first or request exception

    Step therapy (ST) is specified for some products. When ST appears, the Plan requires trial of specified preferred products before covering the non‑preferred product. Providers may request an exception with clinical justification if the preferred agent is inappropriate.

    • ST examples include AUVELITY and select sedative/hypnotic agents; follow the table row for which agent(s) must be tried first.
    • If a prescriber requests an exception because a step drug is expected to harm or has failed, submit the supporting statement; standard and expedited timelines apply.
    Step Therapy

    Step/Benefit Design Indicators — follow specified rules

    Some entries show step or benefit design indicators such as B/D PA, MO, LA, or NDS; follow the step/brand rules when they are specified for an entry. If no explicit step algorithm is listed, use the preferred alternatives listed in nearby entries or contact the Plan.

    • Benefit/design routing (B/D PA) may determine whether a drug is payable under medical or pharmacy benefits.
    • When step therapy or brand rules are present, ensure prior trials and dates are clearly documented in the PA submission.
    Denial Risk

    Authorization and Denial Triggers — denial risk if controls not followed

    The Drug List includes denial and authorization triggers. Missing a required PA, exceeding QL, noncompliance with ST, or failure to follow MO/LA billing routes can result in claim denial.

    • If a cover rule (PA, QL, ST, MO) is not followed, the request may be denied.
    • Providers and pharmacies should verify UM controls prior to dispensing to avoid coverage risk.
    Prior Authorization

    Prior Authorization and Utilization Management Flags — required UM actions

    Required utilization management (UM) actions include following PA, MO, ST, QL, NDS and LA as listed. The Plan may require medical review or routing of certain claims to the medical benefit.

    • Follow the listed UM flags for each drug entry; UM noncompliance may lead to denial.
    • When multiple flags appear (e.g., PA; MO; QL; NDS), complete all required actions before dispensing.
    Note

    Medical Override / Review Where Indicated (MO)

    When a drug entry includes Medical Override (MO) or indicates medical‑only billing, contact the Plan's provider helpdesk for authorization direction and billing pathway. Some items may be available via mail order or medical benefit only.

    • MO may indicate mail‑order or that medical benefit billing is required rather than retail pharmacy.
    • Medical override/review may be available where clinically indicated; submit documentation per Plan instructions.
    Denial Risk

    Requests May Be Denied If Prior Authorization or Documentation Is Missing

    Requests for PA, exceptions, or to exceed QL may be denied if the required PA, documentation, prior therapy trials, or clinical justification are not submitted. Expedited reviews are available when prescriber attests that delay may harm the member.

    • Standard exception decision timeline: up to 72 hours after receiving prescriber's supporting statement.
    • Expedited exception: decision within 24 hours if prescriber supports urgent need.
    • Denials for noncompliance with UM controls may be appealed per Member Handbook.
    Prior Authorization

    Rescue Medications — PA + QL may apply

    Some drugs listed as 'rescue' or emergency rescue medications carry both PA and QL controls; review the entry carefully and obtain PA when indicated and document quantity limits.

    • Example entries: intranasal or rectal rescue benzodiazepines and certain seizure rescue meds (e.g., NAYZILAM, VALTOCO) list PA; MO; QL values.
    • Ensure adequate documentation if requesting quantities above listed QL for rescue therapy.
    Note

    Table Restriction Flags — NDS and days' supply limits

    When following the table, ensure you observe Non‑Extended Days' Supply (NDS) restrictions — some products are limited to 30 days supply at retail or mail‑order and may have stricter refill rules.

    • NDS entries often accompany PA/MO/QL flags; confirm days' supply rules during PA submission.
    • Failure to observe NDS limits can lead to pharmacy claim rejection.
    Note

    When a Drug Entry Lists 'Name of Drug = ...' — apply referenced controls

    If a table row shows coverage mappings such as 'Name of Drug = [other drug]', providers should treat the mapping as an equivalence and apply the listed controls and restrictions of the referenced product.

    • These mappings are used for alternate formulations or branded/generic cross‑references — apply the controls from the referenced name.
    • When mappings are ambiguous, contact Member Services for clarification before dispensing.
    Step Therapy

    Follow Step/Brand and Benefit/Design Controls

    Follow step/brand routing and benefit/design controls (B/D PA, MO, ST) when they are specified. Some entries use routing flags to determine preferred agents or benefit responsibility.

    • Benefit/Design or step controls may affect prior authorization requirements and coverage determination.
    • Providers should document prior trials and reasons for brand use when requesting PA or exception.
    Documentation Required

    Quantity Limits Require Supporting Documentation

    Quantity limits require supporting documentation when requesting a quantity above the published QL. Examples in the list include oncology, anti‑infective, and chronic therapy QLs — include dosing schedule and clinical rationale in the PA.

    • Examples: QL (240 per 30 days), QL (120 per 30 days), QL (28 per 28 days) — these are product‑specific.
    • Supporting documentation examples: dosing charts, treatment plan, prior authorization forms, and prescriber notes.
    Prior Authorization

    Required Utilization Management Actions — follow PA, MO, ST, QL, NDS

    Required UM actions (PA, MO, ST, QL, NDS) must be completed per the table. Noncompliance with utilization controls or failure to obtain PA can result in denial or non‑coverage.

    • Verify all applicable flags on the drug entry before dispensing.
    • If unsure, contact Member Services to confirm required UM steps.
    Note

    Non‑Narcotic Analgesics and Alternatives — follow MO/MCD/QL controls

    Some non‑narcotic analgesics and alternative therapies have MO/MCD designations and quantity limits listed; follow the entry controls and submit documentation when seeking coverage exceptions.

    • Examples include acetaminophen liquids, aspirin formulations, and other OTC analgesics flagged MCD; MO.
    • For Medicaid‑only (MCD) items, different appeal rules may apply — see the Member Handbook.
    Step Therapy

    Step Therapy Present for Some Agents — document prior trials or request exception

    Step therapy is present for select agents across therapeutic areas (examples include AUVELITY, certain benzodiazepine liquid formulations, and RALDESY). When ST applies, document prior trials or request an exception with prescriber rationale.

    • ST entries require trial and failure or intolerance of preferred agents before covering the non‑preferred product.
    • Provide dates and outcomes of prior therapies in the PA or exception request.
    Prior Authorization

    Prior Authorization for Specialty/Oncology and Select Products

    Some specialty and oncology agents are routinely PA‑required and may carry B/D PA, MO, LA, QL and NDS flags. Verify the listed controls for each specialty product and route PA and billing per Plan instructions.

    • Examples include ADCETRIS, DARZALEX, BORTEZOMIB, and many oral oncolytics (entries show PA; MO; QL; NDS).
    • Specialty products may require medical benefit routing or limited‑availability (LA) pharmacy fulfillment.

    Step Therapy Rules and Tables

    Step therapy where indicated

    Where step therapy is indicated

    Step therapy requirement: Products marked 'ST' require documented trial and failure of specified preferred agent(s) before coverage of the next-line agent will be provided.per product

    Example: RALDESY is labeled with ST; prescriber must document prior trial of preferred therapy or request an exception.

    RequirementDetail
    Member must try required step therapies unless an exception is granted
    Plan allows prescriber to request an exception when first-line therapy is inappropriate; see exception process and timelines.
    Policy statementExample / implication
    Plan may require trying specified drugs first (Step Therapy - ST) before covering alternatives.
    Example: AUVELITY is marked ST in the drug list; Drug B may be covered only after trial/failure of the preferred agent(s).
    FlagContext in drug list
    NDS
    MO
    Flags observedInterpretation
    MO; PA
    Indicate medical-only routing and prior authorization processes; explicit step hierarchy is not shown in the excerpt—follow formulary entry and PA procedures.
    Agent typeNotations / implications
    Oncology and specialty agents
    Annotated with B/D PA, NDS, LA — indicates benefit/design restrictions, prior authorization and specialty routing may apply.
    Entry flagsMeaning
    MO
    LA or MO/LA — denote medical override or limited access, suggesting requirements prior to approval for certain lines or formulations.
    NotationImplication
    B/D PA
    B/D PA and MO imply additional benefit-design routing or specialty program requirements before coverage is granted.
    Observed flagsCoverage implication
    B/D PA; MO
    These flags indicate benefit-design or medical-only controls that affect coverage pathways; follow drug-specific entries for actions required.
    FlagOperational effect
    B/D PA; MO
    Products marked with these flags require routing through benefit/diagnosis prior authorization or medical-only review before coverage.
    ObservationNote
    No explicit step therapy sequences shown in excerpt
    'Name of Drug' mappings and ST flags on some rows imply preferred alternatives and where step requirements exist providers must follow the formulary listing.
    RequirementExamples
    Prior Authorization and/or Medical Override required before coverage
    Many specialty neurological agents (e.g., brivaracetam listings) show PA; MO and QL that must be met prior to coverage.
    Product groupFormulary indication
    Non-narcotic analgesics and OTC options
    Listed with MCD or MO suggesting preference for non-narcotic first-line options and associated utilization controls (e.g., acetaminophen entries with MCD/MO).
    Products with STNotes
    AUVELITY; certain diazepam presentations; DRIZALMA
    Listed with ST flags in the drug list—prescriber must meet step requirements for coverage where indicated.
    ST examplesRequirement
    RALDESY
    Marked ST in the list; prescriber must satisfy step therapy requirements prior to coverage.
    Authorization flagsExample
    PA; MO; LA; NDS
    Example: DOPTELET pack variants show PA; MO; LA; NDS — requirements depend on the specific pack/formulation.

    Quantity Limits by Product and Formulation

    Quantity limits — general (varies by drug)
    General statementQuantity limits vary by drug — limits and required actions (PA, MO, NDS) are specified in each drug row of the Drug List
    Where to find detailsSee the List of Covered Drugs tables for drug-specific QL values and related utilization controls
    Provider actions linked to QLRequests exceeding QL require supporting documentation and may need PA or MO per formulary guidance
    itraconazole oral capsule (example QL values)
    Itraconazole exampleitraconazole oral capsule — MO; QL (120 per 30 days)
    Alternate itraconazole noteSome antifungal entries show QL (96 per 30 days) for other formulations (see amphotericin/liposome row)
    LocationAntifungal section of Drug List — check specific capsule/solution rows for exact QL
    LEDIPASVIR-SOFOSBUVIR example QL
    LEDIPASVIR‑SOFOSBUVIR QLLEDIPASVIR‑SOFOSBUVIR — PA; MO; QL (28 per 28 days); NDS
    Alternate listingAlso shows QL (11 per 30 days) in table mapping; confirm exact row for dispensing period
    SectionHepatitis/antiviral entries in Drug List
    MAVYRET ORAL PELLETS example QL
    MAVYRET pellets QLMAVYRET ORAL PELLETS — PA; MO; QL (168 per 28 days); NDS
    Pack mappingPellet packet row shows 168/28; other mapping may show QL (11 per 30 days) for alternate pack sizes
    Where shownAntiviral section (HIV/HCV therapies)
    MAVYRET ORAL TABLET example QL
    MAVYRET tablet QLMAVYRET ORAL TABLET — PA; MO; QL (84 per 28 days)
    Alternate mappingSome rows also show QL (11 per 30 days) in mapping fields; verify correct presentation
    SectionAntiviral table — review specific tablet row for dispensing limit
    valacyclovir 1 g QL example
    Valacyclovir 1 g QLvalacyclovir oral tablet 1 gram — MO; QL (120 per 30 days)
    MO noteRow lists MO in addition to QL; prior authorization may be required in some cases
    SectionAntiviral/herpes agents section
    valacyclovir 500 mg QL example
    Valacyclovir 500 mg QLvalacyclovir oral tablet 500 mg — MO; QL (60 per 30 days)
    Related 1 g rowSee 1 g row showing QL 120/30 for higher-dose preparation
    SectionAntiviral section
    azithromycin examples (QL 84/56 etc.)
    Azithromycin exampleazithromycin oral tablet — PA; MO; LA; QL (84 per 56 days)
    Multiple formulationsSome azithromycin rows show varied QL by pack/presentation — check specific formulation row
    SectionAnti‑infectives: macrolides and related entries
    fidaxomicin/tinidazole/TOBI PODHALER/tobramycin/vancomycin examples
    Fidaxomicin / tinidazole / inhaled antibioticsExamples include QL (20 per 10 days) for tinidazole; TOBI PODHALER — QL (224 per 56 days); tobramycin inhalation — QL (4 per 10 days)
    Vancomycin IV entriesVancomycin IV piggyback rows show high-range QLs (4000 per 10 days; 80 per 10 days; 1000 per 10 days depending on concentration)
    Tobramycin injection QLstobramycin injection recon soln — PA; QL (9 per 14 days) or MO; QL (10 per 10 days) alternate rows
    meropenem IV QL examples
    Meropenem IV QL examplesmeropenem IV recon soln — PA; QL (30 per 10 days) or PA; MO; QL (60 per 30 days) in alternate rows
    Use cautionDifferent rows reflect differing QL depending on formulation/setting (e.g., inpatient vs outpatient)
    SectionAnti‑infectives IV formulations
    tobramycin sulfate injection recon soln QL examples
    Tobramycin injection recon soln QLstobramycin sulfate injection recon soln — PA; QL (9 per 14 days); alternate entry — MO; QL (10 per 10 days)
    Other tobramycin entriesTobramycin 10 mg/ml — PA; QL (27 per 10 days); 40 mg/ml — PA; MO; QL (40 per 10 days)
    SectionAminoglycoside injections
    vancomycin IV piggyback QL examples
    Vancomycin IV piggyback QLsVancomycin IV piggyback examples: QL (4000 per 10 days); PA; MO; QL (80 per 10 days); QL (1000 per 10 days); QL (9 per 30 days)
    Alternate piggyback rowsSome piggyback presentations show QL (4050 per 10 days) or QL (90 per 30 days) depending on concentration and mapping
    SectionGlycopeptides/IV antibiotics
    ALUNBRIG QL examples
    ALUNBRIG QL examplesALUNBRIG oral tablet — PA; QL (30 per 30 days) or QL (60 per 30 days) depending on strength/formulation
    ALUNBRIG alternate packsDose‑pack entries show QL (30 per 180 days) in some mappings; check exact row
    SectionOncology targeted agents
    ADCETRIS QL example
    ADCETRIS QLADCETRIS — B/D PA; MO; NDS; QL (66 per 28 days) (example listed)
    Oncology PA flagsMany ADCETRIS entries also show PA/B/D PA and NDS alongside QL
    SectionOncology antibody‑drug conjugates
    Multiple QL examples (60/30;240/30;180/30;112/28;30/30;120/30)
    Multiple QL patternsExamples include QL (60 per 30 days); QL (240 per 30 days); QL (180 per 30 days); QL (112 per 28 days); QL (30 per 30 days); QL (120 per 30 days)
    ContextThese represent varied oncology and specialty drug QLs across formulations — verify drug row for exact value
    ActionRequests exceeding these QLs will require documentation and may need PA/MO
    gemcitabine IV solution QL examples
    Gemcitabine IV QLgemcitabine intravenous solution — PA; QL (120 per 30 days); alternate entries show QL (21 per 28 days) or QL (90 per 30 days) depending on formulation
    B/D PA noteSome gemcitabine rows also list B/D PA; MO; NDS
    SectionAntineoplastic IV solutions
    IMBRUVICA capsule QL example
    IMBRUVICA 70 mg QLIMBRUVICA oral capsule 70 mg — PA; QL (28 per 28 days); NDS
    Other strengthsHigher‑strength tablet/suspension rows show similar QL patterns (e.g., QL 28/28) and B/D PA flags
    SectionOral oncology agents
    LUMAKRAS QL examples by strength
    LUMAKRAS strength QLsLUMAKRAS — 120 mg: QL (240 per 30 days); 240 mg: QL (120 per 30 days); 320 mg: QL (90 per 30 days)
    NDS/PA flagsEach LUMAKRAS row also lists PA; MO; NDS in the formulary
    SectionTargeted oral oncology agents
    LUNSUMIO QL example
    LUNSUMIO QLLUNSUMIO — PA; MO; QL (1260 per 30 days); NDS
    Repeated entryDose and pack variants (VELO) show same QL (1260 per 30 days)
    SectionImmunotherapy/biologic agents
    LUMAKRAS 120 mg QL
    LUMAKRAS 120 mgQL (240 per 30 days)
    ContextListed under LUMAKRAS entries with PA; MO; NDS
    SectionOncology targeted therapies
    LUMAKRAS 240 mg QL
    LUMAKRAS 240 mgQL (120 per 30 days)
    ContextSee adjacent LUMAKRAS rows for strength‑specific QLs and flags
    SectionOncology targeted therapies
    LUMAKRAS 320 mg QL
    LUMAKRAS 320 mgQL (90 per 30 days)
    ContextStrength‑dependent QL shown in Drug List entries
    SectionOncology targeted therapies
    LUNSUMIO QL example (1260)
    LUNSUMIO repeatLUNSUMIO — QL (1260 per 30 days)
    FlaggingPA; MO; NDS accompany this high QL in formulary rows
    SectionBiologic therapies
    LYNPARZA QL example
    LYNPARZA QLLYNPARZA — PA; MO; QL (120 per 30 days)
    Alternate rowsSome LYNPARZA rows show lower per‑period caps (e.g., 30 per 30 days) for certain formulations
    SectionPARP inhibitor entries
    methotrexate injection QL example
    Methotrexate injection QLmethotrexate sodium (pf) injection recon soln — PA; MO; QL (2 per 28 days)
    Dose-specific noteSmall per‑period QL reflecting injectable dosing conventions
    SectionAntineoplastic injectables
    MODEYSO QL example
    MODEYSO QLMODEYSO — PA; QL (20 per 28 days); NDS
    Alternate pack QLsSome MODEYSO rows show QL (3 per 28 days) for certain pack types
    SectionOncology oral agents
    PEMAZYRE QL example
    PEMAZYRE QLPEMAZYRE — PA; LA; QL (28 per 28 days); NDS
    Pemetrexed related rowsPemetrexed rows list B/D PA; MO; NDS with varying QLs
    SectionRare tumor agents
    PIQRAY QL example
    PIQRAY QLPIQRAY oral tablet 200 mg/day — PA; QL (28 per 28 days); NDS
    Higher-dose rowsPIQRAY 250/300 mg rows list QL (56 per 28 days) and up to QL (120 per 30 days) for other formulations
    SectionPI3K inhibitors and related agents
    pomalidomide QL example
    Pomalidomide QLpomalidomide — PA; MO; QL (21 per 28 days); alternate QL (240 per 30 days) appears for some mappings
    Use notePomalidomide entries include REMS/monitoring flags in full table
    SectionImmunomodulatory agents
    REZUROCK QL example
    REZUROCK QLREZUROCK — PA; LA; QL (30 per 30 days); NDS
    Related injectionsREZUROCK rows associate with long‑acting injectables in name mapping lines
    SectionEndocrine/peptide agents
    ROZLYTREK QL example
    ROZLYTREK QLsROZLYTREK oral capsule 100 mg — PA; MO; QL (150 per 30 days); other strengths list QL (120 per 30) or QL (90 per 30)
    Pellet packet examplesROZLYTREK oral pellets show very large QLs in packet form (e.g., QL (336 per 28) or QL (300 per 30) depending on pack)
    SectionOncology targeted kinase inhibitors
    RYDAPT / RYLAZE / sunitinib QL examples
    RYDAPT QLRYDAPT — PA; MO; QL (224 per 28 days); NDS
    RYLAZE QLRYLAZE — PA; MO; QL (120 per 30 days); NDS
    Sunitinib QLsunitinib malate — PA; MO; QL (28 per 28 days)
    VENCLEXTA QL example
    VENCLEXTA QLVENCLEXTA oral tablet 100 mg — QL (180 per 30 days)
    UNITUXIN/other oncologyMultiple oncology injectables show PA/MO and varying QLs — check row for strength
    SectionHematologic oncology agents
    BRIVIACT IV/oral QL examples
    BRIVIACT QLsBRIVIACT IV — MO; QL (600 per 30 days); BRIVIACT oral/tablet rows include QL (60 per 30 days) and larger listings by formulation
    Brivaracetam oral tabletOral tablet — MO; QL (60 per 30 days); some formulations list QL (90/30) or higher
    SectionAntiepileptic agents
    clobazam formulations QL examples
    Clobazam QLsclobazam oral suspension/tablet rows — PA; MO; QL (480 per 30 days) or PA; LA; QL (360 per 30 days) for other formulations
    Formulation varianceDifferent formulations (suspension vs tablet) show substantially different QLs
    SectionAntiepileptic agents — clobazam
    gabapentin solutions/tablets QL examples
    Gabapentin QLsgabapentin solutions/tablets — examples include QL (2160 per 30 days) for solution; QL (270 per 30 days); QL (360 per 30 days) depending on strength/formulation
    Extended release examplesExtended‑release 600 mg — PA; MO; QL (90 per 30 days)
    SectionNeurology/anticonvulsants
    NAYZILAM, VALTOCO QL examples (10/30)
    NAYZILAM / VALTOCO QLNAYZILAM and VALTOCO — PA; MO; QL (10 per 30 days)
    Rescue medication noteThese rescue/acute seizure agents are explicitly limited to 10 doses per 30 days in listed rows
    SectionSeizure rescue therapies
    valproic acid oral solution QL example
    Valproic acid solution QLValproic acid oral solution — PA; LA; QL (1100 per 30 days) for specified concentrations
    VALTOCO mappingVALTOCO rows show PA; MO; QL (10 per 30 days) for some presentations
    SectionAntiepileptic formulations
    valproic acid / VALTOCO QL examples
    VALTOCO/valproate noteVALTOCO — PA; MO; QL (10 per 30 days); valproic acid solution shows higher QLs (e.g., 1100/30) depending on concentration
    Provider actionPA and documentation required for requests exceeding QL
    SectionSeizure therapies
    AUSTEDO XR TITRATION KT QL example
    AUSTEDO XR titration kitAUSTEDO XR TITRATION KT — PA; MO; QL (28 per 180 days); other formulations — QL (30 per 30 days)
    Tetrabenazine QLtetrabenazine 25 mg — QL (120 per 30 days) or 240 per 30 days for other strengths
    SectionMovement disorders — tetrabenazine, deutetrabenazine, valbenazine
    tetrabenazine 25 mg QL example
    Tetrabenazine 25 mg QLtetrabenazine oral tablet 25 mg — PA; MO; QL (240 per 30 days)
    Alternate strengthsTetrabenazine 12.5/25 mg rows show QL (120 per 30 days) for some presentations
    SectionHyperkinetic movement disorder agents
    acetaminophen-codeine QL example
    Acetaminophen‑codeine QLacetaminophen‑codeine oral solution — MO; QL (4500 per 30 days) (example shown)
    BELBUCA QLsBELBUCA — PA; MO; QL (60 per 30 days) or alternative QL (50 per 30 days); other formulations QL (4 per 28 days)
    SectionAnalgesics and combination opioids
    BELBUCA / fentanyl QL examples
    BELBUCA pack QLsBELBUCA buprenorphine entries — QL examples: 60 per 30 days; 50 per 30 days; 4 per 28 days depending on formulation
    Fentanyl patchfentanyl transdermal patch 72 hr — QL (10 per 30 days); alternate mapping shows QL (2400 per 30 days) for other codes
    SectionOpioid analgesics and buprenorphine products
    fentanyl / hydrocodone / methadone QL examples
    Fentanyl & hydrocodone examplesfentanyl patch — QL (10 per 30 days); hydrocodone‑acetaminophen oral solution — high QLs (5550 per 30 days) with alternate entries QL (180 per 30 days)
    Hydromorphone ER QLhydromorphone ER 24 hr — PA; MO; QL (60 per 30 days)
    Methadone rangesmethadone formulations — QL examples include 90/30; 120/30; 240/30; 900/30; 1200/30 depending on product
    ASIMTUFII IM formulation QL examples
    ASIMTUFII IM QLsASIMTUFII intramuscular suspension — examples: QL (30 per 30 days); QL (60 per 30 days); QL (4.8 per 365 days); QL (1.6 per 28 days); QL (3.2 per 56 days)
    Multiple syringe QLsDifferent syringe sizes/strengths show distinct fractional QLs (per 28/56/365 days)
    SectionLong‑acting injectable antipsychotics
    diazepam oral solution QL examples
    Diazepam oral solution QLsdiazepam oral solution — PA; MO; QL (1200 per 30 days) on one row; ST and QL (30 per 30 days) for other presentations
    Diazepam concentrate rowsOral concentrate rows show QL (240 per 30 days) or QL (30 per 30 days) depending on mapping
    SectionBenzodiazepine liquid/concentrate entries
    INVEGA SUSTENNA / TRINZA and injectables examples
    INVEGA SUSTENNA/TRINZA fractional QLsExamples: QL (0.5 per 28 days); QL (0.88 per 90 days); QL (1.32 per 90 days); QL (1.75 per 90 days); QL (2.63 per 90 days); QL (1.5 per 28 days)
    Higher per‑period capsOther INVEGA TRINZA rows show QL (60 per 30 days) or QL (150 per 30 days) depending on syringe size
    SectionLong‑acting injectable antipsychotics — IM formulations
    Various oral agents QL examples
    Various oral agents QLsExamples include QL (30 per 30 days); QL (60 per 30 days); QL (120 per 30 days); QL (28 per 365 days); QL (14 per 365 days)
    RALDESY ST flagRALDESY — ST; MO; NDS with QL (120 per 30 days) on alternate row
    Risperidone microspheresrisperidone microspheres IM extended — QL (2 per 28 days)
    amlodipine-valsartan and related QL examples
    Amlodipine‑valsartan QLamlodipine‑valsartan — QL (4 per 28 days)
    Doxazosin QLsdoxazosin oral tablet 1‑4 mg — QL (30 per 30 days); doxazosin 8 mg — QL (60 per 30 days)
    DOPTELET pack variantsDOPTELET formulations — QL varies by pack (examples: QL 28 per 28 days; QL 22.4 per 28 days)
    Note

    Site-of-Care Routing and Coverage Considerations

    Note
    Note
    Note
    Note

    Background and Scope

    Background: This document is the Plan's List of Covered Drugs and provides the formulary for HAP CareSource MI Coordinated Health including prescription drugs, certain OTC drugs and selected non‑drug OTC items. It explains coverage rules, utilization controls (PA, ST, QL, NDS, MO), and member/provider actions required to obtain coverage. Providers and members should consult the full Drug List and legend for symbol definitions and the most recent update.

    Definitions and Table Abbreviations

    Biosimilars and Benefit Routing

    Billing Rule

    Biosimilar substitution subject to state law

    Biosimilars may be used in place of original biological products; state law may affect interchangeability and substitution practices at the pharmacy.