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    v1.0.28
    OpenPayerPolicy UpdatesPharmacy & Specialty Drugscareoregon desmopressin Prior Auth Coverage | Open…
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    CurrentcareoregonPolicy N/A

    Desmopressin prior authorization

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    Defines prior authorization requirements for desmopressin products (nasal spray and nasal solution) for members of CareOregon; governs coverage criteria and approval lengths for specified diagnoses.

    Policy Summary
    Payercareoregon
    PolicyDesmopressin prior authorization
    Policy CodePolicy N/A
    Change TypeNo material changes
    Effective DateJul 1, 2026
    Next Review DateN/A
    Key ActionObtain prior authorization and document the specific desmopressin product and the diagnosis when requesting approval.
    SourceLink
    POLICY UPDATE CHANGES

    No material clinical or coverage changes in this revision.

    Lifetimestandard approval length
    0.01% / 1.5 mg/mLlisted desmopressin formulations
    Hem A; VWD 1 & 2explicit covered diagnoses

    Coverage criteria

    Initial Coverage Criteria

    Covered when ALL of the following are met

    Desmopressin product: Request is for generic desmopressin 0.01% nasal spray OR generic desmopressin 1.5 mg/mL nasal solution
    Covered diagnoses: Diagnosis is Hemophilia A OR Von Willebrand disease type 1 OR Von Willebrand disease type 2
    Approval length: Lifetime (through 12/31/2039)

    Coverage is limited to requests for generic desmopressin 0.01% nasal spray or generic desmopressin 1.5 mg/mL nasal solution when prescribed for one of the listed diagnoses. The only covered indications specified are Hemophilia A, Von Willebrand disease type 1, and Von Willebrand disease type 2.

    The policy does not enumerate additional specific exclusions or conditions labeled as not medically necessary. In practice, any use that does not meet the listed product and diagnosis criteria above is outside the scope of coverage under this guideline.

    Policy Summary
    Payercareoregon
    PolicyDesmopressin prior authorization
    Policy CodePolicy N/A
    Change TypeNo material changes
    Effective DateJul 1, 2026
    Next Review DateN/A
    Key ActionObtain prior authorization and document the specific desmopressin product and the diagnosis when requesting approval.
    SourceLink
    On This Page
    Coverage criteriaCodingProvider actions and requirementsBackgroundDefinitions and formulationsInitial therapyContinuation and renewalStep therapy

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    Coding

    No codes listedmixed
    No codes listed

    Provider actions and requirements

    Prior Authorization

    Prior authorization required; approvals = Lifetime

    Prior authorization is required for the listed desmopressin indications; when approved, authorizations are issued for a lifetime through 12/31/2039.

    Step Therapy

    No step therapy required

    No step therapy requirements are specified in this guideline for the listed desmopressin products.

    Documentation Required

    Document product and diagnosis on PA request

    When requesting prior authorization, document the specific desmopressin product formulation and the member’s diagnosis (e.g., generic desmopressin 0.01% nasal spray or generic desmopressin 1.5 mg/mL nasal solution for Hemophilia A or Von Willebrand disease type 1 or 2).

    Denial Risk

    Prior authorization required for listed desmopressin products

    Prior authorization must be obtained for the desmopressin products and indications listed in this guideline; requests without PA may be denied.

    Background

    Desmopressin is included in the guideline as two intranasal formulations: generic desmopressin 0.01% nasal spray and generic desmopressin 1.5 mg/mL nasal solution. The policy frames these products for treatment of bleeding disorders and specifically lists their use for Hemophilia A and Von Willebrand disease types 1 and 2. The document focuses on prior authorization and approval duration for these formulations rather than on detailed clinical management.

    Definitions and formulations

    Desmopressin formulations
    FormulationGeneric desmopressin 0.01% nasal spray
    FormulationGeneric desmopressin 1.5 mg/mL nasal solution
    Drug classDesmopressin (vasopressin analog) — nasal formulations

    Initial therapy

    Initial Therapy

    Initial authorization

    Product and diagnosis: Request is for one of the specified desmopressin formulations (generic desmopressin 0.01% nasal spray or generic desmopressin 1.5 mg/mL nasal solution) AND the diagnosis is Hemophilia A, Von Willebrand disease type 1, or Von Willebrand disease type 2
    Approval duration: If criteria are met, approval length is Lifetime (through 12/31/2039)

    Continuation and renewal

    Continuation Therapy

    Continuation/renewal information

    Continuation approval: Approvals for the listed desmopressin products and covered diagnoses are issued for a lifetime (through 12/31/2039)

    Step therapy

    StepRequirement
    No step therapy requirements specifiedThe guideline does not list any step therapy steps for desmopressin; requests are handled per prior authorization criteria