Radiation Treatment for Selected Nononcologic Indications
Customize your policy alerts
Sign up for Aetna Policy 0551 alerts
Get alerted when Policy 0551 changes without checking for updates manually.
Monitor payer policy activity
Defines Aetna's coverage stance for radiation treatments used for specified noncancer conditions (e.g., keloids, heterotopic ossification, pterygium, plantar fibromatosis, osteoarthritis) including when therapy is considered medically necessary or experimental; affects providers submitting claims to Aetna.
No material clinical or coverage changes in this revision.
Coverage Criteria
Initial coverage criteria
Covered when ALL of the following are met for each indicated condition:
See CPB 0031 for indications for keloid removal.
High-risk features include previous heterotopic ossification, ankylosing spondylitis, diffuse idiopathic skeletal hyperostosis or spinal stenosis, unlimited hip motion preoperatively, and head injury.
Strontium-90 regimens and low-dose fractionation schedules are discussed in background evidence.
Experimental, investigational, or unproven
See related CPBs for additional context.
Evidence-supported uses and emerging/experimental indications
Evidence summaries and suggested indications from the literature
References include Guix et al, De Cicco et al, van Leeuwen et al.
Friedman et al 2017; Geddes-Bruce 2018.
Cuculich et al 2017 and subsequent case reports/reviews.
Schuster et al 2015; DEGRO summaries.
Yu et al 2021; Dove et al 2022.
Eekers et al 2018.
Ablative radiotherapy delivered using CPT codes 77373 and 77435 is listed in this Clinical Policy Bulletin as not covered when used for the indications addressed by this policy. Claims submitted using these codes for experimental or unproven indications discussed here (for example, stereotactic/ablative radiotherapy for cardiac arrhythmias) may be denied because effectiveness for those indications has not been established.
The policy text does not list broad categorical exclusions beyond the specific procedural/code-based exclusion noted elsewhere; however, several clinical uses discussed in the background are characterized as early-stage or investigational and require further validation (examples include noninvasive cardiac radio-ablation for ventricular tachycardia and radiotherapy for drug‑resistant focal epilepsy). These indications are described in the background evidence summaries as preliminary, requiring larger or randomized trials before routine coverage can be assumed.
This Clinical Policy Bulletin (CPB) provides a summary of Aetna's coverage position for radiation treatments used for selected nononcologic indications. It is intended to assist in administering plan benefits and does not constitute an offer of coverage, medical advice, or a contract. Treating providers remain responsible for medical advice and treatment decisions, and the CPB may be updated over time.
The policy explicitly considers the TRASER device for nasal telangiectasias and ablative radiotherapy for cardiac arrhythmia to be experimental, investigational, or unproven because their effectiveness has not been established. As such, use of these modalities for the listed indications is not considered medically necessary under this CPB.
Several therapies discussed in the background are described as having preliminary or limited evidence rather than being explicitly labeled 'not medically necessary' in every instance. For example, single‑fraction SBRT (25 Gy) for refractory ventricular tachycardia and radiotherapy approaches for drug‑resistant focal epilepsy have encouraging case series or systematic reviews but are characterized as early evidence needing prospective validation; the CPB therefore treats them as investigational or requiring further study.
Coding
| 77402-77417 | Radiation treatment delivery [includes beta irradiation]. |
| 77436 | Surface radiation therapy; superficial or orthovoltage, treatment planning and simulation-aided field setting. |
| 77437 | Surface radiation therapy; superficial, delivery, ≤150 kV, per fraction (eg, electronic brachytherapy). |
| 77438 | Surface radiation therapy; orthovoltage, delivery, >150-500 kV, per fraction. |
| 77439 | Surface radiation therapy; superficial or orthovoltage, image guidance, ultrasound for placement of radiation therapy fields for treatment of cutaneous tumors, per course of treatment (List separately in addition to code for primary procedure). |
| 77767-77772 | Remote afterloading high dose rate radionuclide skin surface brachytherapy, includes basic dosimetry, when performed. |
| 77778 | Interstitial radiation source application, complex, includes supervision, handling, loading of radiation source, when performed. |
| 77373 | Stereotactic body radiation therapy, treatment delivery, per fraction to 1 or more lesions, including image guidance, entire course not to exceed 5 fractions [ablative radiotherapy]. |
| 77435 | Stereotactic body radiation therapy, treatment management, per treatment course, to 1 or more lesions, including image guidance, entire course not to exceed 5 fractions [ablative radiotherapy]. |
| L91.0 | Hypertrophic scar [keloid]. |
| M15.0-M19.93 | Osteoarthritis. |
| M08.1 | Juvenile arthritis code listed (document context unclear). |
| M45.0-M45.9 | Ankylosing spondylitis. |
| M48.00-M48.08 | Spinal stenosis. |
| M72.2 | Plantar fascial fibromatosis. |
| S06.0x0A-S06.9x9S | Intracranial injury (head injury range). |
| I78.1 | Nevus. |
| I49.01-I49.9 | Other cardiac arrhythmias. |
| No codes listed |
Provider Actions and Documentation
Prior authorization expected for listed radiation procedure codes
Prior authorization is implied for the CPT/HCPCS codes listed as covered (e.g., 77402-77417, 77436-77439, 77767-77772, 77778) when those services are billed for the CPB-covered indications; selection criteria in the policy must be met before treatment is considered medically necessary.
- Covered CPT ranges: 77402-77417, 77436-77439, 77767-77772, 77778 (see coding section).
- Ensure documentation supports that the member meets the condition-specific selection criteria in the policy (e.g., keloid excision within 7 days, osteoarthritis age and prior therapy requirements, high-risk features for HO).
No explicit prior-authorization process stated for experimental indications
The policy text includes clinical series and background but does not specify additional or separate prior-authorization rules or a distinct prior authorization process tied to specific experimental indications described in the background.
- Case series (e.g., single-fraction 25 Gy SBRT for cardiac VT) are described in background without stating a separate PA requirement or defined PA pathway for those experimental uses.
Policy does not define additional CPT/HCPCS PA-trigger codes
Across the policy background and history there are no explicit, additional lists of CPT/HCPCS codes that trigger prior authorization beyond the covered and not-covered code listings provided in the coding section.
- Policy coding tables list covered and not-covered CPT codes but do not add separate PA-trigger code lists in the narrative background or policy history.
Stepwise treatment required before radiation for osteoarthritis
For osteoarthritis, radiation therapy is considered only after a stepwise trial of therapies: inadequate response to non-pharmacologic therapies, then inadequate response/intolerance/contraindication to pharmacologic therapies, and after orthopedic surgical evaluation that deems the patient medically inoperable for joint replacement.
- Document inadequate response to non-pharmacologic therapies (e.g., physical therapy, exercise).
- Document inadequate response, intolerance, or contraindication to pharmacologic therapies (e.g., topical/systemic analgesics, intra-articular glucocorticoids).
- Include orthopedic surgeon consultation indicating disease advanced enough for joint replacement but patient is medically inoperable.
Conservative therapies must be tried before low-dose radiotherapy for OA
Background and guidance indicate low-dose radiotherapy (LDRT) for osteoarthritis is intended for patients refractory to conventional conservative therapies; providers should document trials of exercise, physical therapy, and NSAIDs (or intolerance) before LDRT is considered.
- Record conservative therapies attempted and duration (e.g., exercise, physical therapy, NSAIDs).
- Document rationale for selecting LDRT (joint selection, impact on quality of life, prior therapy response).
Keloid excision + postoperative radiation: document CPB 0031 indications and treatment within 7 days
When postoperative radiation is given for keloids, documentation must show the excision met medical necessity criteria for keloid removal per CPB 0031 and that radiation was delivered within the policy-specified window (within 7 days after excision).
- Reference CPB 0031 to demonstrate medically necessary indication for keloid excision.
- Document timing of radiation relative to excision (treatment within 7 days per policy).
- Include radiation regimen details (e.g., HDR brachytherapy schedules cited in background such as 12 Gy in 4 fractions or 18 Gy in 6 fractions when applicable).
Osteoarthritis documentation: age and failed therapies required
For osteoarthritis claims, include documentation that the member is at least 60 years old and that prior non-pharmacologic and pharmacologic therapies failed or were not tolerated; also include the orthopedic surgeon evaluation stating the patient is medically inoperable for joint replacement.
- Member age (≥ 60 years).
- Records of non-pharmacologic therapy attempts and outcomes.
- Records of pharmacologic therapy trials, intolerances, or contraindications.
- Orthopedic surgeon consultation findings and operative candidacy determination.
HO prophylaxis: document high-risk features to support medical necessity
When radiation is used for heterotopic ossification (HO) prophylaxis, document the presence of high-risk features (for example: prior HO, ankylosing spondylitis, diffuse idiopathic skeletal hyperostosis, spinal stenosis, unlimited pre-op hip motion, or head injury) to support medical necessity.
- List and document high-risk features present in the patient.
- Include surgical context and timing of prophylactic radiation relative to surgery as applicable.
Document treatment regimens, dose schemes, and follow-up schedules in the record
Medical records should include treatment reports specifying the regimen, dose/fractionation scheme, and planned follow-up schedule; background examples (HDR brachytherapy fractionation, electron RT schemes, LDRT fraction sizes) are referenced and should be recorded in the chart when used.
- Specify radiation modality, total dose, fractions, and timing (e.g., HDR brachytherapy 12 Gy in 4 fractions; electron RT schemes 21 Gy in 7 fractions or 30 Gy in 10 fractions; LDRT typically 0.5 Gy/fraction).
- Document follow-up plan and outcome assessments used in cited series (e.g., follow-up intervals used in Guix et al.).
Policy history provided — no extra documentation obligations in history section
Policy history and review links are provided in the document header and history section, but these sections do not impose additional clinical documentation requirements beyond those already stated.
- Review dates and links are for reference; they do not change the documentation expectations in the clinical criteria.
Coding-related denial risk for not-covered ablative/SBRT CPT codes
Claims submitted with CPT codes listed as not covered for the CPB indications (for example, ablative radiotherapy codes 77373 and 77435 used for cardiac arrhythmia) are at risk of denial when those experimental/unproven indications are billed.
Background case-series do not constitute PA or denial triggers
Several background sections and series describe clinical experience without stating specific prior-authorization or denial triggers; these background-only descriptions do not themselves create authorization rules.
- Treat background reports (case series, observational data) as clinical context rather than PA policy language.
- Rely on the policy's coverage criteria and coding tables to determine medical necessity and appropriate billing.
Background
Keloids are benign, proliferative dermal scars with a high likelihood of recurrence after excision. The CPB states that postoperative radiation (low‑ or high‑dose, superficial or interstitial) given promptly after excision (within 7 days) reduces recurrence and is considered medically necessary when keloid removal itself meets medical necessity criteria (see CPB 0031).
Definitions
Revision History
Policy became effective.
Policy last reviewed on 07/30/2026.
Next scheduled policy review date is 06/10/2027.
OpenPayer is powered by Trek Health's payer performance platform. Trek continuously ingests, validates, and normalizes Transparency in Coverage data alongside payer policies and other commercial payer data to create a structured payer intelligence foundation. OpenPayer uses this foundation to deliver personalized search results, dynamically generated policy pages, and tailored policy monitoring based on each user's payers, specialties, billing codes, and areas of interest. The same intelligence powers broader payer performance workflows, including reimbursement benchmarking, contract evaluation, payer negotiations, and financial decision-making.