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    v1.0.28
    OpenPayerNPI Medicare & MedicaidPanayotis Ledakis
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    Panayotis Ledakis — Billing Profile & Reimbursement Data

    NPI 1649385634 · Baltimore, MD · Hematology & Oncology Physician

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    Panayotis Ledakis is a hematology & oncology physician provider located in Baltimore, Maryland. This profile covers 46 Medicare and 0 Medicaid CPT/HCPCS procedure codes, with claims volume, average reimbursement, and total revenue by code, benchmarked against other providers billing the same services.

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    Provider details (source: NPPES NPI Registry)

    FieldValue
    Entity TypeIndividual
    OrganizationPanayotis Ledakis
    Address227 St Paul Place
    CityBaltimore
    StateMD
    ZIP21202
    TaxonomyHematology & Oncology Physician
    NPI EnumeratedAugust 20, 2006

    Lifetime revenue by payer source (source: CMS Medicare & Medicaid claims data)

    Payer SourceTotal Paid
    Medicare$3M
    Medicaid$0

    Key Findings

    This provider’s Medicare business is highly concentrated in a small set of oncology drugs: the top 3 Medicare codes (J9271, J9299, J0897) account for 81.2% of total Medicare revenue. Lifetime Medicare revenue is $3M and those three drug codes together dominate the payer relationship, signaling dependence on high-cost oncologic infusions for revenue generation.

    Code-level detail shows pembrolizumab (J9271) is the single largest revenue driver with $1.4M in Medicare revenue and 33.6K claims; this provider ranks #78 of 1841 nationally (96th percentile) and is described as notably above typical national volume for this code. Nivolumab (J9299) contributes $558.7K across 23.3K claims and ranks #124 of 505 (76th percentile), a typical national volume position, while denosumab (J0897) generates $354.2K from 19.7K claims and ranks #299 of 10057 (97th percentile), also notably above typical national volume.

    The procedure mix and claim counts indicate an infusion-centric oncology practice: there are 632 claims for chemotherapy administration (96413, $68.3K revenue), 746 claims for IV push follow-on doses (96375, $9.7K), and multiple other infusion-related codes such as 96372 (624 claims, $6.9K) and 96365 (232 claims, $12.3K). These volumes are consistent with an outpatient infusion suite model that administers checkpoint inhibitors and supportive agents rather than a clinic focused only on office-based management.

    Supportive-care biologics are a visible secondary line of business: pegfilgrastim (J2506) shows 984 claims and $82.7K in Medicare revenue with a national rank of #33 of 586 (95th percentile), flagged as notably above typical national volume, and darbepoetin alfa (J0881) appears with 39.1K claims and $78.2K revenue (rank #114 of 1114, 90th percentile). This pattern reinforces a combined oncology and supportive-care service line that manages chemotherapy-induced neutropenia and anemia.

    Clinical E/M activity includes a heavy share of higher-complexity office visits: 99214 has 1.4K claims and $124.4K revenue and is flagged as an extreme outlier (rank #4488 of 479517, 99th percentile), while 99205 and 99215 also appear among the top codes (162 claims/$25.3K and 135 claims/$16.7K respectively). The unusually high relative volume for 99214 suggests frequent complex follow-up visits accompanying infusion services, rather than a minimal consult-only practice.

    Competitive standing is mixed by code: the provider is a strong national performer for J9271 (96th percentile) and J0897 (97th percentile), indicating market-leading activity for those specific oncology drugs, while activity for J9299 sits at a more typical 76th percentile. Several infusion and supportive codes (for example J2506 at the 95th percentile and 96413 at the 95th percentile) further indicate the provider operates at above-typical scale in selected Medicare oncology services.

    Payer mix is effectively single-payer on file: Medicare is the only recorded payer with $3M in lifetime revenue and there is explicitly no Medicaid billing on file. From a contracting and risk perspective, the provider is therefore functionally Medicare-dependent and has no Medicaid revenue to offset Medicare exposure.

    Tenure and registration history show an established practice footprint: the NPI was enumerated on 2006-08-20 (~20 years ago), indicating long-standing Medicare participation that aligns with the sustained high volumes in oncology infusions and supportive-care biologics reported above.

    Medicare: Total Revenue Breakdown by CPT/HCPCS Code

    Medicare revenue breakdown by CPT/HCPCS procedure code.

    View: Bar Chart1 / 2

    Medicare: Complete Services Breakdown

    The CPT/HCPCS codes generating the most Medicare revenue for this provider.

    46 rows

    CPT/HCPCS CodeDescriptionClaimsAvg PaidRevenue
    J9271Injection, pembrolizumab, 1 mg33,600$40$1.4M
    J9299Injection, nivolumab, 1 mg23,280$20$558.7K
    J0897Injection, denosumab, 1 mg19,680$20$354.2K
    99214The provider sees an established patient for an office visit or other outpatient visit involving evaluation and management. The visit involves a moderate level of medical decision making, and/or the…1,400$90$124.4K
    J2506Injection, pegfilgrastim, excludes biosimilar, 0.5 mg980$80$82.7K
    J0881Injection, darbepoetin alfa, 1 microgram (non-esrd use)39,100$1$78.2K
    96413Chemotherapy is a therapeutic procedure used for the treatment of cancer via the use of chemical agents. These chemical agents (drugs) work on the cancerous cells of the body to destroy them. These…630$110$68.3K
    J2796Injection, romiplostim, 10 micrograms850$70$62.1K
    99205The provider sees a new patient for an office visit or other outpatient visit involving evaluation and management. The visit involves a high level of medical decision making, and/or the provider…160$160$25.3K
    99215The provider sees an established patient for an office visit or other outpatient visit involving evaluation and management. The visit involves a high level of medical decision making, and/or the…140$120$16.7K

    Showing 1–10 of 46

    Medicare: Competitive Analysis & Benchmarks

    How this provider's Medicare billing volume and revenue compare to other providers nationally and within its state, across 46 CPT/HCPCS codes.

    View: State1 / 2

    Full comparison — all codes billed, vs. state median

    46 rows

    CPT/HCPCS CodeRankProvider CountMedian ClaimsAvg PaidAverage Revenue
    J927166015,000$40$787.6K
    J9299132024,080$20$660.6K
    J27962103,450$70$252.3K
    J0897213403,600$20$114.4K
    J0881226030,420$1$76.4K
    J34904110070$450$62.1K
    J2506430590$80$55.2K
    9641321230200$110$29.6K
    J921797100150$130$27.3K
    9921420110,270150$90$24.1K

    Showing 1–10 of 46

    Related Providers

    Other providers that share a Tax Identification Number (TIN) with Panayotis Ledakis, ranked by combined Medicare and Medicaid revenue.

    ProviderStateTaxonomyMedicare RevenueMedicaid Revenue
    St Paul Place Specialists, Inc.MDDermatology Physician$0$13.3M
    Michael MorrisMDDiagnostic Radiology Physician$12M$0
    Richard HusligMDHematology & Oncology Physician$4.9M$0
    St Paul Place Specialists, Inc.MDClinical Pathology/Laboratory Medicine Physician$2.7M$948.8K
    Jaideep SohiILNuclear Radiology Physician$1.5M$6.9K
    Kelly OrwatSCInternal Medicine Physician$1.3M$0
    Jonathan BreslauMNDiagnostic Radiology Physician$1.3M$0
    Muhammad Saad KhanILHematology & Oncology Physician$1.3M$0
    Stephen RonsonMDSpecialist$1.2M$0
    Pavni PatelMDNuclear Medicine Physician$1.1M$0

    Nearby Providers

    Other providers in the same ZIP code as Panayotis Ledakis, ranked by combined Medicare and Medicaid revenue.

    ProviderStateTaxonomyMedicare RevenueMedicaid Revenue
    Baltimore City SchoolsMDLocal Education Agency (LEA)$0$95.8M
    Mayor And City Council Of BaltimoreMDLand Ambulance$6.3M$38M
    Health Care For The Homeless, IncMDFederally Qualified Health Center (FQHC)$0$26.8M
    Maryland Family Care, Inc.MDFamily Medicine Physician$0$24.6M
    Hope Resource Center, LLCMDCommunity/Behavioral Health Agency$0$18.1M
    Pha Healthcare LLCMDSubstance Use Disorder Rehabilitation Clinic/Center$0$18M
    Lighthouse Behavioral Health Center, LLCMDSubstance Abuse Rehabilitation Facility$0$11.5M
    Emergency Physicians SppsMDEmergency Medicine Physician$0$9.8M
    Heavens Place-outpatient Detox & Recovery CenterMDMental Health Clinic/Center (Including Community Mental Health Center)$0$7.6M
    S K Pesis Dds, Big Smiles Maryland, PCMDDentist$0$6.9M

    Frequently Asked Questions

    References

    1. 1.Medicare Physician & Other Practitioner by Provider and Service. CMS.gov.Provider-level Medicare Part B utilization and payment data.
    2. 2.NPPES NPI Registry. CMS.gov.National Provider Identifier registry used for provider enumeration and taxonomy metadata.

    Trek Health ingests and normalizes Transparency in Coverage data and payer policy updates to give provider organizations a clear view of how commercial reimbursement behaves across markets, payers, and services. Our platform transforms raw payer disclosures into structured intelligence that supports contract evaluation, payer negotiations, and service line strategy. By combining market benchmarks with ongoing policy visibility, Trek helps teams identify variability, risk, and opportunity in commercial reimbursement. The result is faster insight, stronger negotiating positions, and more informed financial decisions.

    Medicare Revenue by CPT/HCPCS Code
    Claims Volume vs. Maryland Distribution
    Panayotis Ledakis — 4 of 25 codes billed far more than typical (above p95)
    p5–p95 (all providers)p25–p75MedianThis providerOutlier
    Rank Distribution — Maryland