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    v1.0.28
    OpenPayerBilling CodesPersons with potential health hazards related to family and personal history and certain conditions influencing health statusICD-10-CM z80-family-history-of-cancer
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    ICD-10-CM Code For Family History Of Primary Malignant Neoplasm: Group Overview

    The International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) code group Z80 includes codes for a personal record of family history of primary malignant neoplasm, specifying relatives with various site-specific cancers and a family history of malignant neoplasm of unspecified site. These ICD-10-CM diagnosis codes are used to document the presence of a family history that may affect screening, surveillance, and management decisions, capturing relevant clinical context rather than active disease. Accurate coding within the ICD-10-CM Z80 group supports appropriate claim adjudication, complete clinical documentation, and correct reimbursement.

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    ICD-10-CM Z80: Family History Of Primary Malignant Neoplasm Overview

    This diagnostic group documents a patients family history of primary malignant neoplasm, indicating biological relatives with a diagnosis of cancer that may influence risk assessment. The codes target oncologic family history across organ systems rather than active malignancy in the patient. Accurate coding supports risk stratification, clinical decision-making, and correct reimbursement processing when family history affects care planning.

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    When to Use

    Use a code from this group when a patients record documents a family member with a history of primary malignant neoplasm that is relevant to screening, risk assessment, or management. These codes are appropriate when family history is confirmed and affects clinical decisions, even though the patient does not have an active malignancy.

    ICD-10-CM Codes

    16 rows

    ICD-10-CM CodeDescription
    Z80.0Family history of malignant neoplasm of digestive organs
    Z80.1Family history of malignant neoplasm of trachea, bronchus and lung
    Z80.2Family history of malignant neoplasm of other respiratory and intrathoracic organs
    Z80.3Family history of malignant neoplasm of breast
    Z80.41Family history of malignant neoplasm of ovary
    Z80.42Family history of malignant neoplasm of prostate
    Z80.43Family history of malignant neoplasm of testis
    Z80.44Family history of malignant neoplasm of fallopian tube(s)
    Z80.49Family history of malignant neoplasm of other genital organs
    Z80.51Family history of malignant neoplasm of kidney
    Z80.52Family history of malignant neoplasm of bladder
    Z80.59Family history of malignant neoplasm of other urinary tract organ
    Z80.6Family history of leukemia
    Z80.7Family history of other malignant neoplasms of lymphoid, hematopoietic and related tissues
    Z80.8Family history of malignant neoplasm of other organs or systems
    Z80.9Family history of malignant neoplasm, unspecified

    DRG Codes

    1 rows

    DRG CodeDescription
    951Other Factors Influencing Health Status

    Typical Clinical Scenarios

    • An asymptomatic adult woman presents to her primary care provider for a routine well visit and requests guidance on cancer screening because her mother was diagnosed with breast cancer at age 45; family history is reviewed and documented to guide screening frequency and risk counseling. A family history diagnosis is assigned to capture the documented first-degree relative with primary malignant neoplasm and to support preventive care planning. Typical codes: Z80.3, Z80.42
    • A middle-aged man is referred to a genetics clinic after his father and paternal grandfather were both diagnosed with colorectal cancer in their 50s; the patient reports no current symptoms but seeks evaluation for hereditary cancer syndromes and possible earlier colonoscopy surveillance. The family history code is recorded to indicate multiple first-degree or second-degree relatives with primary malignant neoplasms and to justify genetic risk assessment. Typical codes: Z80.0, Z80.6
    • An elderly patient is admitted to the hospital with pneumonia and has a past documented family history of prostate cancer noted in the medication reconciliation and social history; the presence of a documented family history is included on the problem list as a comorbidity affecting long-term care and screening considerations. A family history code is assigned to capture the relevant family cancer history in the inpatient record. Typical codes: Z80.51, Z80.9

    Related Codes

    Z77-OTHER-CONTACT-WITH-EXPOSURES

    ICD-10-CM Code For Other Contact With And Suspected Exposures Hazardous To Health: Group Overview

    Z78-OTHER-SPECIFIED-HEALTH-STATUS

    ICD-10-CM Code For Other Specified Health Status: Group Overview

    Z79-LONG-TERM-DRUG-THERAPY

    ICD-10-CM Code For Long Term Current Drug Therapy: Group Overview

    Z81-FAMILY-HISTORY-OF-MENTAL-DISORDERS

    ICD-10-CM Code For Family History Of Mental And Behavioral Disorders: Group Overview

    Z82-FAMILY-HISTORY-OF-DISABILITIES

    ICD-10-CM Code For Family History Of Certain Disabilities And Chronic Diseases: Group Overview

    Z83-FAMILY-HISTORY-OF-OTHER-SPECIFIC-DISORDERS

    ICD-10-CM Code For Family History Of Other Specific Disorders: Group Overview

    Z84-FAMILY-HISTORY-OTHER-CONDITIONS

    ICD-10-CM Code For Family History Of Other Conditions: Group Overview

    Z85-PERSONAL-HISTORY-OF-MALIGNANT-NEOPLASM

    ICD-10-CM Code For Personal History Of Malignant Neoplasm: Group Overview

    Z86-PERSONAL-HISTORY-OF-CERTAIN-DISEASES

    ICD-10-CM Code For Personal History Of Certain Other Diseases: Group Overview

    Z87-PERSONAL-HISTORY-OF-OTHER-DISEASES

    ICD-10-CM Code For Personal History Of Other Diseases And Conditions: Group Overview

    Showing 1–10 of 22

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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